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3 articles for “single-cell sequencing”
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Clone-Specific Drug Delivery Systems: Targeted Approaches and Future Clinical Applications
Abstract: Clone-specific drug delivery systems represent a transformative frontier in personalized medicine, addressing the longstanding challenge of clonal heterogeneity within diseases such as cancer, infectious diseases, and autoimmune disorders. Traditional drug delivery platforms often fail to discriminate between pathogenic and healthy cells, leading to systemic toxicity and reduced therapeutic efficacy. In contrast, clone-specific systems aim to selectively target and eliminate disease-driving cellular clones based on unique molecular signatures, thereby improving treatment …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 21–29 Read article
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Single-Cell Genomics and its Impact on Understanding Cellular Heterogeneity
Abstract: Single-cell genomics has transformed how we study the differences between individual cells, helping scientists uncover the detailed variety within tissues that traditional methods could not reveal. Traditional methods, such as RNA sequencing, average gene expression across many cells, thereby missing subtle yet important cellular variations. Single-cell technologies, such as single-cell RNA sequencing (scRNA-seq), DNA sequencing, and epigenomics, allow researchers to study individual cells in extraordinary detail like never before. This …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 1–5 Read article
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A Review Paper on Lean Manufacturing Implementation Techniques
Abstract: Lean manufacturing was initially designed to reduce waste and maximise resource usage. Later, lean wasdeveloped in response to the competitive and ever-changing business environment. Organizations are compelled to deal with difficulties and complications because of the business environment's rapid change. The ability of any business, whether manufacturing- or service-focused, to consistently and methodically adapt to these changes in order to increase the value of its products may ultimately determine whether …
Published in Recent Trends in Fluid Mechanics · Vol. 11, Issue 2, 2024 · pp. 1–9 Read article