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3 articles for “retrovirus.”
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Biochemical and Biophysical Studies of the Dimerization Process of HIV-RNA Genome
Abstract: HIV infection is correlated with the dimerization of retroviral RNA genomes.Retroviruses are the only known group of viruses that contain two identical (or nearly identical) copies of the RNA genome within the virion. These RNA genomes are non-covalently joined together through a process known as genomic RNA dimerization. Uniquely, the RNA dimerization of the retroviral genome is of crucial importance for efficient retroviral replication. RNA dimerization is the non-covalent process …
Published in Research and Reviews: A Journal of Medicine · Vol. 1, Issue 2, 2011 · pp. 9–15 Read article
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Transgenic or Genetically Modified Farm Animals and their Applications: A Review
Abstract: Abstract Transgenic are genetically modified organisms having DNA from different source introduced into their genome. Genetic alteration of livestock species is advantageous to human health as important pharmaceutical proteins can be produced in economic and efficient ways. Transgenic animals like mice, rat and hamster etc. are also used to study human diseases. Transgenic livestock species comprised of different kinds of animals are modified with the purpose of improving economically important …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 5, Issue 3, 2016 · pp. 25–34 Read article
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Advancing Gene Therapy: Next-Generation Viral Vector Engineering for Precision, Safety, and Scalability
Abstract: Gene therapy has emerged as a paradigm-shifting modality for the treatment of genetic disorders, malignancies, and rare diseases through the delivery of therapeutic nucleic acids aimed at correcting or modulating dysfunctional gene expression. Among the various delivery systems, viral vectors including adeno-associated viruses (AAVs), lentiviruses, adenoviruses, retroviruses, and herpes simplex viruses have proven indispensable owing to their high transduction efficiencies and adaptability. This review offers a comprehensive assessment of viral …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 37–55 Read article