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7 articles for “ocular surface”
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Dry Eye Disease: A Common Ophthalmic Problem
Abstract: Dry eye is a multifactorial disorder of tears and ocular surface caused due to unstable tear film giving rise to chronic dryness of cornea and conjunctiva. and in turn causes a feeling of dryness, foreign body sensation, pain, redness, burning, and light sensitivity. It can lead to serious complications like a corneal ulcer, which result in blindness if timely treatment is not given. The dry eye disease prevalence ranges up …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 12, Issue 2, 2022 · pp. 26–33 Read article
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Preservatives for Ocular Drug Delivery System
Abstract: Most challenge faced today is in ocular drug delivery. Topical eye drop is the most convenient and patient compliant route of drug administration, especially for the treatment of anterior segment diseases. Delivery of drugs to the targeted ocular tissues is restricted by various precorneal, dynamic and static ocular barriers. Also, therapeutic drug levels are not maintained for longer duration in target tissues. In the past two decades, ocular drug delivery …
Published in Trends in Drug Delivery · Vol. 7, Issue 3, 2020 · pp. 1–5 Read article
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Ocular Inserts: An Overview
Abstract: Ocular inserts are sterile preparations which are to be placed into cul-de-sac or conjuctival sac. The major aim of ocular insert is to maintain a therapeutic level at the site of action for prolonged period of time. The therapeutic efficacy of an ocular drug can be greatly improved by prolonging its contact with the corneal surface. Ocular insert gives several advantages like increased ocular residence time, drug release at a …
Published in Trends in Drug Delivery · Vol. 4, Issue 2, 2017 · pp. 20–22 Read article
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Ocular Films as a Drug Delivery System Against Fungal Infections: Current Insights and Future Directions
Abstract: Fungal infections of the eye, including keratitis, endophthalmitis, and blepharitis, represent a challenging class of ocular diseases due to their potential for vision loss and the limited efficacy of existing treatments. These infections are caused by a range of pathogenic fungi, such as Aspergillus, Candida, and Fusarium species, and often require long-term therapeutic intervention. Conventional topical antifungal therapies, such as eye drops and ointments, suffer from poor ocular bioavailability due …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 101–109 Read article
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Role of Netra Tarpana with Triphala Ghrita in Dry Eye: A Clinico-Pathological Evaluation
Abstract: Dry eye syndrome is a very common condition that is characterized by a disturbance of the tear film. There is not a single entity which can be compared as dry eye but a group of diseases or stages of diseases which are more or less similar to dry eye like Sushkaksipaka, Pothaki, Suktika. Preservative-free tear substitutes are the first step in medical management of DED which increases humidity and improves …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 4, Issue 3, 2015 · pp. 1–8 Read article
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Demodex spp. (Acari: Demodicidae) Infestation in Humans: Diagnostic Clues and Therapeutic Approaches to Primary and Secondary Demodicosis.
Abstract: Demodicosis represents an inflammatory dermatosis and adnexal disorder arising from pathologic overgrowth of Demodex mites, primarily Demodex folliculorum and Demodex brevis, which are ubiquitous human ectoparasites residing in pilosebaceous units and eyelid margins. Once regarded as benign commensals, these mites are now recognized as primary drivers or key cofactors in diverse clinical phenotypes, including papulopustular eruptions, pityriasis folliculorum, rosacea-like disorders, blepharitis, meibomian gland dysfunction, and exacerbations of comorbid dermatoses such …
Published in International Journal of Insects · Vol. 3, Issue 1, 2026 · pp. 12–20 Read article
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A Review on Novel Emulsification Technique: A Nanoemulsion
Abstract: Kinetically stable and isotropic system of submicron size range is the nanoemulsion. In this system two immiscible liquids are mixed together to form a single-phase system with the identical concentration and ratio of surfactant and cosurfactant. Nanoemulsion droplet sizes fall typically in the range of 20- 200 nm. Some literature suggest this range below 100 nm with shows narrow size distribution. In this review, major focus is given on the …
Published in Trends in Drug Delivery · Vol. 3, Issue 2, 2016 · pp. 25–34 Read article