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4 articles for “hereditary case”
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Breast Cancer: Susceptible Genes and Significant Risk Factors
Abstract: Breast cancer is the most common malignancy affecting women globally. In 2012, around 1.67 million new cases were reported worldwide. With the increase in life expectancy in developed countries, the incidence of breast cancer among older adults has risen significantly. In 2017, an estimated 252,710 new cases of invasive breast cancer were recorded, along with 6,341 cases of breast cancer in situ in the USA. About 24% of all breast …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 2, 2024 · pp. 36–43 Read article
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The Curious Case of the Sphered Blood Cells: Unveiling Hereditary Spherocytosis
Abstract: Hereditary spherocytosis (HS) is an inherited blood disorder that disrupts the shape and flexibility of red blood cells (RBCs) due to genetic mutations. These abnormal, sphere-shaped RBCs, called spherocytes, are prematurely destroyed in the spleen, leading to hemolytic anemia. Symptoms range from mild fatigue to chronic weakness and shortness of breath. While incurable, Hereditary spherocytosis can be effectively managed. Regular monitoring, folic acid supplementation, and in severe cases, splenectomy (surgical …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 49–57 Read article
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Identification and Characterization of Genetic Predictors of Sickle Cell Anemia in Bilaspur District, Chhattisgarh, India
Abstract: In the present decades, sickle cell anemia (SCA) is a challenging task for control of hereditary syndrome in Bilaspur district of Chhattisgarh state, India. The present study aims to identify and characterize genetic predictors of SCA from Bilaspur district (CG) in 2024. A total of 3000+ individuals were screened and categorized into carriers, positive (screening), and diseased cases. Fetal hemoglobin (HbF) level is determined by several genetic factors including genetic …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 2, 2026 · pp. 1–9 Read article
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Description & Prevention of Omicron
Abstract: November 9, 2021, Botswana becomes the first country to recognise it (Nov 11 2021). The new variant (B.1.529) has been represented in 77 countries. Omicron presents 32 changes in spike protein Scribd, restricting the point of interaction with the ACE2 receptor protein. Computational shows and components’ recreation has been applied to investigate the collaboration between the SARS-CoV-2 RBD and the ACE2 receptor. The receptor-binding domain (RBD), which more barely joins …
Published in Research & Reviews: A Journal of Pharmacognosy Read article