Search
4 articles for “Quorum sensing(QS)”
-
Whispers of the Microbial World: Unveiling Bacterial Dialogues through Quorum Sensing
Abstract: Quorum sensing is a special way of bacteria by which they can regulate their own gene expression as per the population density of the bacteria. It is basically a type of cell-to-cell communication pathway used by the microbes. The signal molecule which helps in this mechanism are called auto inducer(AI). As the mechanism depends by changes in the cell density, so when the cell density reaches to the threshold cell …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 3, 2024 · pp. 1–8 Read article
-
Inhibition of Quorum Sensing to Mitigate the Risks of Membrane Biofouling in Biological Wastewater Treatment
Abstract: Membrane-based systems play a pivotal role in various applications, providing efficient separation, purification, and filtration processes across diverse industries such as water purification and desalination. However, this system faces major challenge of membrane biofouling impacting the efficiency and sustainability of such systems. Biofouling occurs when various microorganisms like bacteria, fungi, etc. adheres to the surface of membrane and form biofilm which results in reducing membrane permeability and increasing its operational …
Published in Research & Reviews : Journal of Ecology · Vol. 13, Issue 1, 2024 · pp. 18–26 Read article
-
Quorum Sensing and Biofilm Dynamics in Pathogens: An Evolving Frontier in Infectious Disease
Abstract: Bacterial and fungal pathogens rarely act as solitary invaders. Instead, they engage in sophisticated chemical communication known as quorum sensing (QS) to coordinate population-wide behaviours and construct structured, multicellular biofilm communities. These biofilms, composed of extracellular polymeric substances, not only facilitate microbial persistence on biotic and abiotic surfaces but also confer remarkable protection against host immune defenses and antimicrobial therapies. QS systems act as central regulators of biofilm dynamics, orchestrating …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 · pp. 18–23 Read article
-
Pharmacokinetic Profiling and Molecular Docking of Carvacrol and Structural Analogs: Targeting Quorum Sensing Proteins to Disrupt Biofilm-Mediated Antimicrobial Resistance in Multidrug-Resistant Bacterial Pathogen
Abstract: Antibiotic resistance, particularly in Pseudomonas aeruginosa, has become a major global health threat, exacerbated by the organism's ability to form biofilms and regulate virulence through quorum sensing (QS). The LuxR and LasR receptors are key regulators in this process, influencing both pathogenicity and antibiotic resistance. This study investigates potential QS inhibitors targeting these receptors as a strategy to mitigate antibiotic resistance. The primary objective was to identify novel ligands that …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 2, 2025 · pp. 43–61 Read article