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4 articles for “Pluronics®”
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Pluronics®-Cyclodextrin Inclusion Complex for Targeted Drug Delivery System
Abstract: Host–Guest’ inclusion complexes have in Pluronics® and Cyclodextrins (CDs) have an enormous research attraction as drug vehicles. In addition, CDs in Pluronics® solutions has captured much attention for the researchers to develop supramolecular biomaterials by improving the solubility and stability of drugs in aqueous and gel medium by Pluronics®-CDs inclusion complexation. Keywords: Supramolecular, Pluronics®, Cyclodextrins (CDs), Inclusion complex
Published in Trends in Drug Delivery · Vol. 5, Issue 3, 2018 · pp. 1–4 Read article
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Engineering of PEG-b-PCL/Pluronic F127 Polymeric Composite Micelles for Controlled Co-Delivery of Docetaxel and Curcumin in Prostate Cancer Therapy
Abstract: Polymeric composite nanocarriers made from amphiphilic block copolymers are popular for their customisable architecture, self-assembly behaviour, and drug release control. A PEG-b-PCL/Pluronic F127 micellar composite was developed and tested as a multifunctional nanocarrier for docetaxel and curcumin administration.The amphiphilic block copolymers Pluronic® F127 and PEG-b-PCL were employed to generate polymeric micelles using solvent evaporation-assisted self-assembly. The optimised polymer composite showed good colloidal stability and uniform size distribution with a zeta …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 Read article
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Preparation of Lipase Loaded Chitosan Nanoparticles and its Estimation Using Different Additives
Abstract: Chitosan nanoparticles were prepared by ionic gelation technique and simultaneously entrapment of lipase was carried out in it. These were then subjected to additives such as surfactants, pluronics and ionic liquids. Activity of lipase was assayed in free as well as immobilized conditions. It was then compared to immobilized enzyme bound to these polymers. The results have been graphically displayed. Among surfactants, tween 80 and triton X-100 were used with …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 6, Issue 2, 2016 · pp. 19–27 Read article
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Formulation Development, Characterization and in-vitro Evaluation of Nano-Lipid Carriers of Ropinirole HCl for Persistent Parkinsonian Management
Abstract: According to a report of World Health Organization (WHO) 2014, Parkinson's Disease (PD) is the second-most neurodegenerative dysfunction of the central nervous system (CNS) of human being effecting 7–10 million people worldwide. It is primarily due to the death of dopamine-generating cells in the substantia-nigra of midbrain. It is symptomatized by tremor, rigidity, bradykinesia, dementia, depression and falls or emerges with the progression of the disease. Ropinirole HCl is a …
Published in Trends in Drug Delivery · Vol. 6, Issue 1, 2019 · pp. 14–23 Read article