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2 articles for “Pair wise Alignment”
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Multiple Sequence Alignment Algorithms for a Protein Structure for a Biological Data using Dynamic Programming Method
Abstract: Many algorithms use dynamic programming to align two sequences. In this paper a new algorithm is proposed to perform multiple Sequence alignment. This algorithm is developed by taking the inspiration of dynamic programming and is implemented on protein structures of any length. It uses particle swarm optimization (PSO) techniques to get the best alignment. The proposed approach tries to improve the sequence alignment obtained by Needleman Wunsch algorithm.
Published in Recent Trends in Programming languages · Vol. 1, Issue 1, 2014 · pp. 4–10 Read article
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Biochemical and Structural Characterization of Helicobacter pylori Peptide deformylase by Computational Methods
Abstract: Helicobacter pylorus is classified as class one carcinogen in causing gastric cancer. Peptide deformylases (PDFs) present in bacteria removes the formyl group from the N-terminal Methionine of newly synthesized proteins which is necessary in protein maturation. These enzymes have shown as new targets in antibacterial, antimalarial and anticancer drug discovery. Here an insilico technique was initiated to characterize structural and biochemical properties of this protein. Pair wise sequence alignment with …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 4, Issue 3, 2017 · pp. 22–28 Read article