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2 articles for “Oxidative stress Radio-resistance”
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Oxidative stress analysis of cancer patient treated with Radiotherapy
Abstract: Oxidative stress is a term given to overload of free radicals in the body caused by an imbalance between levels of free radicals and antioxidants in the body. Reactive Oxygen Species (ROS) are free radicals also known as oxygen radicals that are produced by various physiological reactions inside the body leading to increasing oxidative stress that can lead to cell death. In case of cancer management, radiation therapy works by …
Published in Trends in Drug Delivery · Vol. 10, Issue 1, 2023 · pp. 28–31 Read article
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Cellular Mechanisms of Autophagy in Carcinogenesis: A Narrative Review
Abstract: Autophagy is a highly conserved lysosomal degradation pathway essential for cellular homeostasis, metabolic adaptation, and survival under stress. In the context of carcinogenesis, autophagy exhibits a paradoxical and stage-dependent role. During early tumor development, autophagy acts as a tumor-suppressive mechanism by limiting genomic instability, oxidative stress, and chronic inflammation. Conversely, in established malignancies, cancer cells exploit autophagy to sustain growth, survive hostile tumor microenvironments, and resist anticancer therapies. Increasing evidence …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 1, 2026 · pp. 23–28 Read article