Search results for “New lineages”

Published Subscription Original Research 30 Jun 2025

Live Epidemiological Tracking of COVID-19 in Senegalese Participants of the Hajj

By Dr. Aminata Mboup, Abdou Padane, Dr. Yacine Amet Dia, Mr. Seyni Ndiaye, Dr. Marièma Sarr, M. Marilyne Aza-Gnandji, Mr. Mamadou Ndao, Mr. Abdoulaye Samba Diallo, Mr. Ousmane Diop, Mr. Bacary Dembo Diatta, Mr. Ousmane Diouf, Mr. Abdoulaye Leye Sarr, M. Ndèye Astou Dabo, M. Seynabou Selbé Diouf, M. Aissatou Nogaye Dieng, Mr. Mame Matar Diop, Mr. Abdoulaye Souaré, M. Ndèye Dieynaba Diouf, Dr. Nafissatou Leye, Dr. Astou Gueye, Dr. Aminata Dia, Dr. Mame Sokhna Gueye, Djibril Wade, Cyrille Kouligueul Diédhiou, Ambroise Ahouidi, Papa Alassane Diaw, Badara Cissé, Moustapha Mbow, Boly Diop, Raghavendra G. Amachawadi

Abstract: Background: Since the COVID-19 outbreak, global efforts have focused on controlling the disease. However, intense cross border movements pose a risk for the emergence of new SARS-CoV-2 strains. A recent example is the detection of cases among the 2024 Senegalese pilgrims returning from Mecca, Saudi Arabia. Investigations of these cases have revealed genomic evolution of the virus. The lack of surveillance may lead to the emergence of high-threat strains. This …

Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 8–16 Read article

Published Subscription Review Article 27 May 2024

Viral Chronicles: The Ever-Evolving Saga of COVID-19

By Chandrika Kadam

Abstract: Coronaviruses, belonging to the family of RNA viruses, have recently captured global attention owing to their remarkable ability to infect a diverse array of species, ranging from animals to humans. These viral agents, recognized by their characteristic crown-like morphology when observed through electron microscopy, have a historical association with zoonotic diseases. Previous examples include Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV). The term "Corona" …

Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 16–25 Read article

Published Subscription Original Research 30 Mar 2024

Real Time Characterization of BA.2.86 and Its Variant (JN.1) in Senegal Using Midnight Protocol

By Abdou Padane, Marilyne Aza-Gnandji, Seyni Ndiaye, Marièma Sarr, Cyrille Kouligueul Diedhiou, Astou Gueye, Yacine Amet Dia, Aminata Mboup, Abdoulaye Samba Diallo, Ousmane Diop, Ambroise Ahouidi, Papa Alassane Diaw, Souleymane Mboup

Abstract: During the week ending August 13th, 2023, the most prevalent variant of interest (VOI), uploaded to GISAID, was the BA.2.86 variant. This SARS-CoV-2 Omicron lineage was described as the first phylogenetically distinct from the currently circulating SARS-CoV-2 Omicron XBB lineages, including EG.5.1 and HK.3. Compared to the XBB and BA.2 lineages, the BA.2.86 possesses more than 30 mutations in the Spike (S) protein, suggesting a significant potential for immune evasion. …

Published in International Journal of Vaccines · Vol. 1, Issue 2, 2024 · pp. 16–21 Read article

Published Subscription Original Research 18 Oct 2024

An Evaluative Comparison of CD123 and CD66c as Biomarkers to Detect Minimal Residual Disease in B-Cell Acute Lymphoblastic Leukemia

By Santosh Suman, Sangeeta Pahuja, Shailaja Shukla, Sunita Sharma, Jagdish Chandra, Alice Xalxo

Abstract: Background: B-cell Acute Lymphoblastic Leukemia (B-ALL) often shows lineage heterogeneity with lymphoid cells expressing myeloid markers. Minimal Residual Disease (MRD) refers to the small number of cancer cells that may remain in a patient's body after treatment and that are undetectable by standard diagnostic methods. In diseases like B-cell Acute Lymphoblastic Leukemia (B-ALL), MRD is a critical prognostic indicator, as its presence can signal a higher risk of relapse. In …

Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 · pp. 7–12 Read article