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4 articles for “Leptin”
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Influence of Reptin on acute pancreatitis model of the rat
Abstract: Background and Aim: In acute pancreatitis, hyperproduction of inflammatory mediators, including inflammatory cytokines, exacerbation of tissue injury due to microcirculatory disturbances, secondary activation of inflammatory cells in distant organs, and the cascade are the pathogenic basis of pancreatitis severity. Therefore, inhibition of pancreatic enzyme activity, blocking production, and preventing the activation of inflammatory cells is a practical way to prevent the development of severe acute pancreatitis and multiorgan failure. In …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 11, Issue 2, 2022 · pp. 36–40 Read article
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Smoking and Body Weight: Is There Any Relation?
Abstract: Tobacco is a tall, green leafy plant, originally grown in South and Central America, but now cultivated throughout the world. The link between smoking and body weight is evident as early as adolescence. Nicotine acts on nicotinic cholinergic receptors in the brain and autonomic ganglia. The binding of nicotine to the nicotinic receptors opens ion channels, allowing entry of sodium and calcium, thereby; augment the release of various neurotransmitters. This …
Published in Research and Reviews: A Journal of Health Professions · Vol. 3, Issue 3, 2013 · pp. 33–36 Read article
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Weaning Age Shaping Puberty in Heifer: Insights from Nutritional, Physiological, Hormonal and Environmental Perspectives
Abstract: The onset of puberty in dairy heifers is a critical determinant of their reproductive performance and overall productivity. This study reviews the influence of weaning age on the timing and quality of puberty, synthesizing insights from nutritional, physiological, hormonal, and environmental perspectives. Early or late weaning can significantly impact heifer development, influencing body weight, fat deposition, and metabolic health. Nutrition plays a vital role in shaping growth rates and reproductive …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 14, Issue 1, 2025 · pp. 19–31 Read article
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The Renaissance and Resilience of CB1 Reverse Agonists: From Central Liabilities to Peripheral Promise
Abstract: Building upon these foundational insights, current research has increasingly focused on refining the pharmacological profile of CB1 reverse agonists to maximize therapeutic benefit while minimizing central adverse effects. The adverse neuropsychiatric outcomes associated with first-generation agents such as Rimonabant including anxiety, depression, and suicidal ideation highlighted the critical role of central CB1 receptors in mood regulation. Consequently, drug development strategies have shifted toward peripherally restricted CB1 reverse agonists that exhibit …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 30–35 Read article