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2 articles for “Claisen –Schmidt condensation”
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Synthesis and Evaluation of Chalcone Derivatives and Schiff bases derivatives as Antibacterial
Abstract: AbstractSix substituted chalcones have been synthesized by condensing benzaldehyde derivatives with acetophenone in dilute ethanolic sodium hydroxide solution at room temperature according to Claisen-Schmidt condensation. In addition, four of Schiff bases have been prepared via imine condensation between substituted benzaldehyde firstly with (3) 2-aminophenol, secondly, with phenylhydrazine. Moreover, study the efficient of synthesized compounds as antibacterial agents were evaluated. The structures of the synthesized compounds were confirmed by the melting …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 9, Issue 3, 2018 · pp. 1–7 Read article
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Synthesis, Characterization and Antibacterial Activity of Chalcone Derivatives
Abstract: Chalcone derivatives were produced by the Claisen-Schmidt condensation of aromatic aldehydes with methyl ketones. Chalone derivatives are valuable species as they belong to keto-ethylenic components. Chalcone is a one-of-a-kind template that is linked to a variety of biological processes. 2-hydroxy-2,5- dichloro acetophenon (1) were synthesized by Fries migration and condensed with aromatic aldehyde to produce the new chalcone derivatives (2a-e). The new 1-(2-hydroxy-3,5-dichlorophenyl)-aryl-prop2-ene-1-ones (2a-e) (chalcones) were characterized using FT-IR and …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 14, Issue 2, 2023 · pp. 42–46 Read article