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2 articles for “Carbonic Anhydrase II”

• Published Subscription Original Research 9 Jul 2025

  Investigating The Alkalizing Potential of Chandanasava For Restoring Acid-Base Homeostasis in Renal Tubular Acidosis: A Computational and In Silico Pharmacological Study

  By Nandana V A

  Abstract: Chandanasava, a traditional Ayurvedic formulation, is recognized for its potential alkalizing properties, which may help restore acid-base homeostasis in conditions such as renal tubular acidosis (RTA). This study aims to investigate the active components of Chandanasava and their interactions with key renal target proteins, Pendrin and Carbonic Anhydrase II, which are essential for maintaining acid-base balance. An in silico approach was utilized to explore the pharmacological potential of the phytochemicals …

  Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 28–52 Read article →

• Published Subscription Review Article 2 Jul 2025

  A Review on Kaempferol Eye Drops for the Glaucoma Treatment

  By Rushikesh Chandrakant Sorate, Yashan Kishor Gosavi, Ravikant Siddhappa Bandgar, Prerana Prakash Jadhav, Nikita Ganapat Kasurde, Omkar Maruti Ekamalli

  Abstract: One of the main causes of permanent blindness, glaucoma is defined by gradual damage to the optic nerve, mostly brought on by oxidative stress, neuroinflammation, and high intraocular pressure (IOP). The investigation of herbal alternatives is necessary since current synthetic therapies, such as beta-blockers and prostaglandin analogs, frequently result in ocular discomfort, systemic toxicity, and poor patient compliance. Clitoria ternatea contains kaempferol, a bioactive flavonoid that has shown anti-inflammatory, antioxidant, …

  Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 110–121 Read article →