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6 articles for “Capsaicin”
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Neuropathic Potential of Cabazitaxel Comparative to Paclitaxel and Ameliorative Effect of Capsaicin
Abstract: Paclitaxel and cabazitaxel both are the cytotoxic anticancer drugs having microtubule damaging property. The study aims at comparative neuropathic potential evaluation of cabazitaxel against paclitaxel and to assess the efficacy level of intraperitoneally applied capsaicin isolated from Capsicum annuum seed against both paclitaxel and cabazitaxel-induced neuropathy. Neuropathy was evaluated of heat hyperalgesia, cold allodynia, tactile mechanical hyperalgesia and extent of motor incoordination and motor impairment development on mice. Alternate day …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 5, Issue 2, 2018 · pp. 25–38 Read article
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Cayenne, Capsaicin and Substance-P
Abstract: AbstractCayenne has even been shown to inhibit the itching and pain produced by histamines. Cayenne contains a resinous and pungent substance known as capsaicin. Topical application of capsaicin relieves pain and itching by acting on sensory nerves. t's primary function seems to be the transmission of pain signals. Capsaicin is a remarkable health-promoting substance. The exact mechanism of action of topical capsaicin has not been fully elucidated. Capsaicin is a …
Published in Research & Reviews : Journal of Herbal Science · Vol. 2, Issue 3, 2013 · pp. 11–14 Read article
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Oral Capsaicin Ingestion: A Brief Update Dose, Tolerance and Side Effects
Abstract: Capsaicin has attracted increasing scientific attention in recent years relative to its potential pain relief properties, with oral ingestion providing a useful mode of capsaicin delivery. Yet, despite many exciting new findings in this area, there appears to be significant discrepancy across current research so far about an established oral dosage for use in scientific trials. In an attempt improve future research in this area, this commentary provides a short …
Published in Research & Reviews : Journal of Herbal Science · Vol. 5, Issue 2, 2016 · pp. 1–5 Read article
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The Bhut Jolokia Chilly and the Capsaicin Factor
Abstract: AbstractThe Bhut Jolokia was accepted by Guinness World Records in 2007 as the world’s spiciest chilly. It has a hotness of 1,041,427 SHU (Scoville Heat Units). The chilly is grown and eaten in India’s northeastern states such as Arunachal Pradesh, Assam, Nagaland, Manipur, Meghalaya, Sikkim and Tripura, referred as the hot spots for chilly diversity due to their unique ecological conditions and also, in countries like Bangladesh and Sri Lanka. …
Published in Research & Reviews : Journal of Herbal Science · Vol. 8, Issue 3, 2019 · pp. 9–12 Read article
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Identification of Promising Lead Compounds from Capsicum annuum Targeting BACE-1 for Alzheimer’s Disease Therapy: A Molecular Docking Study
Abstract: Background: Alzheimer's disease (AD) is a neurodegenerative disorder affecting millions of people worldwide. Beta-secretase 1 (BACE-1) is an important therapeutic target for AD treatment. Capsicum annuum (CA) is a commonly consumed plant with potential neuroprotective properties. In this study, we aimed to identify potential lead compounds from CA that can target BACE-1 for AD therapy using molecular docking. Methods: A library of 15 compounds from CA was obtained from PubChem, …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 1, 2023 · pp. 40–49 Read article
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In Silico Analysis of Potential Drug Targets in E. coli as Anticancer Agents
Abstract: Escherichia coli is a bacteria which grows as symbiotic and pathogenic organism in humans that expresses with genes causing several diseases. Manipulation and control of genes of E. coli can become a solution for cure of diseases like cancer. Based on QSAR studies, Partial partial charges are neutral for all selected ligands. The surface area, mass and volume for Capsaicin is predicted more compared to other selected ligands. As the …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 2, 2019 · pp. 10–18 Read article