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1967 articles for “casing” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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In silico Prediction of Two New Conformations of Aβ42 Peptide and Possible Mechanism of Their Aggregation
Abstract: Alzheimer’s disease is one of the most studied neurodegenerative diseases. The cause for most cases of this disease is unknown. However, there are many hypotheses regarding the progression of this disease. One of the hypotheses is the amyloid hypothesis. Amyloid precursor protein present on chromosome 21 is cleaved by β and γ sectretases. The cleaved fragments of this protein, nearly 36–43 residues long aggregates and are deposited as plaque in …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 1, 2019 · pp. 1–7 Read article
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A Consolidated Review on Novel Liquisolid Technique to Enhance Aqueous Solubility of Poorly Water Soluble Drugs
Abstract: Liquid technique is a novel capable method that can change the dissolution rate of water insoluble drugs. Liquid preparations such as solutions or suspensions of water unsolvable drugs in suitable non-volatile liquid vechicles can be transformed into suitable flowing as well as compressible powders by blending with selected powder excipients. It has been speculated that such systems exhibit improved release profiles. In this case, even though the drug is in …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 2, 2019 · pp. 1–4 Read article
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Effects and Awareness of Substandard and Counterfeit Medicines in Indian Scenario
Abstract: In the last decade many cases of counterfeit medicine have been discovered. Studies on privacy and counterfeiting have suggested that up to 20% of all drugs sold in the Indian market are counterfeit. Due to this high counterfeit medication rate the reliability of medical domain is degrading. Drug manufacturers and distributors are increasingly investing in counter-measures, such as traceability and authentication technologies, to try to minimize the impact of counterfeit …
Published in Research and Reviews : Journal of Computational Biology · Vol. 9, Issue 2-3, 2020 · pp. 7–10 Read article
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Computational Biology and Intellectual Property Rights: A Need of the Hour
Abstract: The possibility of the discovery of drugs and cures based on genetic studies that may have the potential to treat diseases hereto considered incurable, has meant an investment of huge amounts in research and development of bioinformatics tools of a more sophisticated, nature which would aid in the field of comparative genomics and such. In this scenario, there has already been a copious amount of funding into research and development …
Published in Research and Reviews : Journal of Computational Biology · Vol. 10, Issue 1, 2021 Read article
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COVID and Computational Biology: A Review
Abstract: The (COVID-19) Corona Virus 19 Disease is infecting millions of people and made several billions to stay at home under Lockdown. The disease has caused global pandemic. The nano-sized virus is threatening the entire human race. It is posing mere burden to the Public, Government, and the health care sectors. The COVID-19 virus is a novel virus, after deep sequencing from samples done by several researchers, and scientist form the …
Published in Research and Reviews : Journal of Computational Biology · Vol. 10, Issue 1, 2021 Read article
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Molecular Evolution of Virulence Genes of Coronavirus: A Computational Study
Abstract: Corona Virus i.e., Covid 19 is consider as highly pathogenic and transmissible, which is responsible for emerging scenario of current pandemic disease. The family of this virus Coronaviridae, which affect respiratory system of human along with animal, and It is belived to be originated from bat. The homology of covid 19 is mix of SARA-CoV and MERS-CoV. The Single-stranded positive genomic RNA, which is coated by nucleocapsid protein is present …
Published in Research and Reviews : Journal of Computational Biology · Vol. 10, Issue 2, 2021 · pp. 22–35 Read article
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To Find the Nucleotide and Protein Sequence of AMYLASE in Homo Sapiens in FASTA Format
Abstract: Comprehensive analysis of current enzymes with α-amylase activity (AAMY) belonging to family 13 of glycoside hydrolases (arrangements of 144 archaea, bacteria, and eukaryotes from different species of GH13; 87). Offers. This study aims to deepen our knowledge of the evolutionary molecular relationships between the sequences of the A and B domains, with a particular focus on the correlation between what is observed in structure and the evolution of proteins. A-domain …
Published in Research and Reviews : Journal of Computational Biology · Vol. 10, Issue 3, 2021 · pp. 13–15 Read article
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Computational Examination of Curcumin Derivatives as Promising Inhibitors for BRCA1 and BRCA2 Proteins in Breast Cancer Treatment
Abstract: Objective: Breast cancer is a major problem for global health and one of the most popular and dangerous diseases. Data from the National Cancer Registry Program (NCRP) of the National Center for Disease Informatics and Research (NCDIR), an arm of the Indian Council of Medical Research (ICMR) in Bangalore, India, shows that an estimated 1,461,427 new cancer cases will occur… Conditions in India by 2022. Among these conditions, breast cancer …
Published in Research and Reviews : Journal of Computational Biology · Vol. 12, Issue 3, 2023 · pp. 68–87 Read article
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Structure based pharmacophore Modelling of compounds against Neurodegenerative disorder – Amyotrophic Lateral sclerosis
Abstract: Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by the progressive degeneration of motor neurons, leading to muscle dysfunction, paralysis, and eventually death. These diseases are classified as ALS variations because autopsies reveal abnormalities in both upper and lower motor neurons. These disorders account for only 10% of all adult-onset motor neuron disease cases. Despite extensive research efforts, effective therapeutic interventions for ALS remain limited. Structure-based pharmacophore modeling …
Published in Research and Reviews : Journal of Computational Biology · Vol. 12, Issue 3, 2023 · pp. 1–17 Read article
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Will Dental Insurance Improve Dental Attendance? Exploring the Patients’ Perspective Attending Outpatient Services of a Dental OPD in Odisha: A Cross-Sectional Survey
Abstract: Background: Not at all like most western nations, particular dental insurance is not regular in India. In India, oral health is ordinarily incorporated with the general medical coverage plans. In any case, with developing awareness about dental care among consumers, there is a requirement for dental coverage. The study was conducted to explore the opinion of patients visiting a dental institution regarding usefulness of dental insurance in availing dental treatments. …
Published in Research and Reviews: A Journal of Dentistry · Vol. 9, Issue 1, 2018 · pp. 11–17 Read article
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Extragingival Pyogenic Granuloma: A Common Lesion in an Uncommon Location
Abstract: Reactive lesions of the oral mucosa are benign and common entities which occur with greater frequency. When the same lesions occur in uncommon sites, they may pose a challenge in diagnosis. One such lesion is the extragingival pyogenic granuloma, which is a counterpart of the most common reactive lesion, the pyogenic granuloma. A case of extragingival pyogenic granuloma occurring on the buccal mucosa of an elderly patient is being presented. …
Published in Research and Reviews: A Journal of Dentistry · Vol. 9, Issue 2, 2018 · pp. 16–19 Read article
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Fabrication of a Feeding Appliance for a Cleft Palate Infant
Abstract: Clefts of the lip, alveolus and palate are the most frequently encountered congenital anomalies of the maxillofacial region. This article presents a case report of a neonate with cleft lip and palate in whom a feeding obturator was delivered Keywords: Cleft lip, cleft palate, feeding obturatorCite this ArticleAkshat Chaudhary, Anubhav Shivpuri. Fabrication of a Feeding Appliance for a Cleft Palate Infant. Research & Reviews: A Journal of Dentistry. 2018; 9(2): …
Published in Research and Reviews: A Journal of Dentistry · Vol. 9, Issue 2, 2018 · pp. 20–22 Read article
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Interceptive Orthodontics A Short Review
Abstract: The term interceptive orthodontics used in this paper is defined as the prompt treatment of unfavourable features of a developing occlusion categorized as local factors, crowding and displacements of the mandible in closing from the rest position. Interceptive orthodontics is defined as a phase of science and art of orthodontics employed to recognize and eliminate the potential irregularities and malpositions in the developing dentofacial complex. Guidance of the eruption and …
Published in Research and Reviews: A Journal of Dentistry · Vol. 2, Issue 1-3, 2011 · pp. 34–38 Read article
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Monostotic Fibrous Dysplasia: Facial Swellings A Diagnostic Conundrum
Abstract: Asymmetrical swelling of the mandible in children may pose a significant diagnostic dilemma. The differential diagnosis ranges from traumatic, infectious, and metabolic processes to benign and malignant tumors that may present with similar clinical and radiological features, making an accurate diagnosis quite difficult. This is an illustrative case involving an 11-year-old girl who initially presented with tumefaction of the mandible and after several investigations and referrals were diagnosed as Monostotic …
Published in Research and Reviews: A Journal of Dentistry · Vol. 2, Issue 1-3, 2011 · pp. 45–49 Read article
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Restoration of Carious Primary Molar Using Two Different Methods
Abstract: Management of dental caries in children using minimally invasive procedures has great importance. For this, various methods have been proposed such as chemo-mechanical methods for caries removal; Carisolv is one of them. The chemo-mechanical method of cavity preparation is considered to be less painful when compared to the traditional treatment method especially in children. In the present article is illustrated the case of a young girl in whom chemo-mechanical caries …
Published in Research and Reviews: A Journal of Dentistry · Vol. 5, Issue 1, 2014 · pp. 15–18 Read article
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Parry–Romberg Syndrome in A Young Male
Abstract: Parry–Romberg syndrome is a condition in which there is slow and progressive shrinkage of the tissues and sometimes bones of one or occasionally both sides of the face. We report a rare case of Parry-Romberg syndrome with trigeminal neuralgia in a 27 year old male with complaints of right sided headache (on and off) and right sided facial pain, which was intermittent and progressive in nature since past 6 months. …
Published in Research and Reviews: A Journal of Dentistry · Vol. 6, Issue 1, 2015 · pp. 14–17 Read article
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Use of Gold in Crown and Bridge Procedures: The Most Versatile Restorative Material in Dentistry: A Review and Commentary
Abstract: Use of gold restorations has been almost forgotten in dentistry. They are no longer a part of most dental training curricula or often employed in private practice. Gold restorations are usually overlooked on most patient treatment plans in modern dentistry largely due to the following misconceptions: Gold is too expensive for use as a dental material. Nonetheless, the price of an ounce of gold in recent months has been at …
Published in Research and Reviews: A Journal of Dentistry · Vol. 7, Issue 1, 2016 · pp. 36–40 Read article
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Rare Representation of Three Mesiodentes: A Supernumerary Challenge
Abstract: Supernumerary teeth are commonly occurring anomaly which is characterised by the presence of additional teeth compared to the conventional dentition. Mesiodens is the most typical supernumerary tooth, located within the premaxilla between the two central incisors. Mesiodentes is seen in a rare condition when mesiodens erupt in multiple numbers. The etiology behind its incidence is obscure and numerous; however the foremost accepted theory is the hyperactivity of the dental lamina. …
Published in Research and Reviews: A Journal of Dentistry · Vol. 8, Issue 2, 2017 · pp. 21–25 Read article
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Management of Basal Cell Adenoma of Parotid Gland with Blair's Incision
Abstract: A basal cell adenoma (BCA) of salivary gland origin is a rare tumour which was included as a separate salivary gland tumour in the classification schemes by the World Health Organization (WHO) in 1991. It is an uncommon benign salivary gland epithelial tumor which accounts for 1–2% of all salivary gland epithelial tumors and more than 80% of BCAs arises in the major salivary glands, mostly the parotid gland. It …
Published in Research and Reviews: A Journal of Dentistry · Vol. 8, Issue 1, 2017 · pp. 9–12 Read article
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Materials used in Periodontal Therapy for the Treatment of Intra-bony Defects
Abstract: Periodontitis is a condition that affects the supporting structures of a tooth, such as the gingiva, cementum, periodontal ligament, and alveolar bone. Periodontitis is widespread in the American population, although most of the cases are mild to moderate in severity and are treatable by minimally invasive procedures. Intra-bony defects, which develop as manifestation of some periodontal diseases, are treated by regenerative therapy with bone grafts that initiate or facilitate the …
Published in Research and Reviews: A Journal of Dentistry · Vol. 10, Issue 3, 2019 · pp. 7–13 Read article