Search
1978 articles for “phosphoinositol-3-kinase pathway” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
Nothing matched all of your words, so these match any of them.
-
Strategic Treatment of COVID-19
Abstract: The novel coronavirus infection, more commonly referred to as COVID-19, the number of people who have died from the coronavirus has now risen to over 1.34 million. Currently there are no approved pharmacological treatments or preventative therapeutic strategies in place to battle the infection. However, globally, research is on-going with the aim to discover effective COVID-19 treatments. The logic behind some of these interventional trials is summarised in this article. …
Published in Research and Reviews: A Journal of Medicine · Vol. 10, Issue 3, 2020 · pp. 35–43 Read article
-
Salivary gland tumors: a retrospective review of 75 cases
Abstract: The objective of this study was to review our recent experience with salivary gland tumors (SGTs). A total number of 75 charts of patients treated for SGTs at the department of otolaryngology-head and neck surgery, Pyongyang Medical College Hospital from January 2011 to December 2015 were retrospectively reviewed. In our series, the average age of patients with SGT was 40.5±12.2 and there was no sexual predilection. The parotid gland was …
Published in Research and Reviews: A Journal of Medicine · Vol. 11, Issue 1, 2021 · pp. 17–21 Read article
-
Prevalence of Lower back pain in a sample population of Musculo-skeletal disorders - Cross sectional community based study
Abstract: Musculoskeletal Disorders (MSD) is a global term for several types of disorders affecting the body’s joints, ligaments, muscles, nerves, tendons and structures that support limbs, neck and back. Low back pain (LBP) is most common musculoskeletal disorder defined as pain and discomfort, localised below the costal margin and above the inferior gluteal folds, with or without referred leg pain.LBP is one of the most common conditions encountered in clinical medicine.LBP …
Published in Research and Reviews: A Journal of Medicine · Vol. 11, Issue 2, 2021 · pp. 38–44 Read article
-
The Clinical Study on Treating Child Chronic Rhinitis with Adenoidectomy
Abstract: Object: We aimed to find out the influences of adenoid hypertrophy on pediatric chronic rhinitis and evaluate the effect for pediatric chronic rhinitis with adenoidectomy. Subjective: We studied is 105 with adenoid hypertrophy among 170 of children with chronic rhinitis. Method: We analyzed the disease associated with chronic rhinitis and compared the group with adenoidectomy to the group with conservative treatment. Results: The mean therapy duration and the recurrence rate …
Published in Research and Reviews: A Journal of Medicine · Vol. 11, Issue 3, 2021 · pp. 31–35 Read article
-
Benign ProstaticHyperplasia–EnhancementinPrevalence,EtiologyandManagement
Abstract: The goal is to learn more about the prevalence, etiology, treatment, and complications of benign prostatic hyperplasia. This is a 6-month retrospective study that covers people who have been diagnosed with BPH. The prevalence, etiology, management, and consequences of benign prostatic hyperplasia were investigated. By recognizing lower urinary tract symptoms and identifying an enlarged prostate, men can receive early treatment and limit the effects of benign prostatic hyperplasia. Benign prostatic …
Published in Research and Reviews: A Journal of Medicine · Vol. 11, Issue 3, 2021 · pp. 1–11 Read article
-
Prenatal estimation of the birth weight above 4,000 g (fetal macrosomia) using fetal abdominal circumference(AC)
Abstract: Purpose: This study is to determine if the birth weight above 4,000g can be correctly estimated by prenatal ultrasonographic measurements of abdominal circumference.Background: The delivery of macrosomatic fetus can increase the perinatal morbidity and mortality of both parturients and fetuses/neonates; the risk for shoulder dystocia, fetal asphyxia and birth trauma as well as vacuum or forceps delivery, hysterotomy and postpartum bleeding due to uterine atony. Thus, the accurate estimation of …
Published in Research and Reviews: A Journal of Medicine · Vol. 12, Issue 3, 2022 · pp. 27–33 Read article
-
Asthma in Children
Abstract: Asthma is described as a disruptive disease of the pulmonary airways attributable to contraction of airway muscle, accelerated mucus secretion, and infection. The airlines of asthmatic individuals are hyper attentive to a variety of stimuli which includes bloodless air, atmospheric irritants. Pharmacologically lively chemicals, numerous drugs, and hyperventilation. Prevalence in numerous populations of kids ranged from I .37% to II .4% or higher. Most studies record a preponderance of allergies …
Published in Research and Reviews: A Journal of Medicine · Vol. 12, Issue 2, 2022 · pp. 20–27 Read article
-
RsaI polymorphisms of ER-β and Idiopathic Male Infertility
Abstract: Purpose: Study on association between estrogen receptor gene polymorphism and male infertility has been interested, but highly specific genetic markers have been reported to be variable according to regions and nations. Herein we studied to figure out whether ERβ gene1082 G>A polymorphism could influence on sperm indices or not.Method: We dealt with 100 Korean patients with idiopathic male infertility diagnosed at our university hospital as a study group and 127 …
Published in Research and Reviews: A Journal of Medicine · Vol. 12, Issue 3, 2022 · pp. 34–41 Read article
-
Efficacy of Chiropractic Combined with Local Ultraviolet Irradiation and Low-frequency Drug Delivery of Huangbaeksu in Knee Synovitis
Abstract: Synovitis of knee joint is an early inflammatory type of osteoarthritis which is a degenerative chronic condition that involves degradation of articular cartilage and synovium, producing joint pain, tenderness, and stiffness. The aim of the present study was to assess the efficacy of chiropractic combined with local ultraviolet irradiation and low-frequency drug delivery of Huangbaeksu in knee synovitis cases. A total of 60 patients with knee synovitis were randomized into …
Published in Research and Reviews: A Journal of Medicine · Vol. 13, Issue 1, 2023 · pp. 1–8 Read article
-
Computational Identification of Protein Tyrosine Phospatase-1B (PTP-1B) Inhibitors for Checking Type II Diabetes
Abstract: Protein tyrosine phosphatases (PTPs) are a family of enzyme that comprises of about 100 proteins which catalyze dephosphorylation of phosphotyrosine residues in protein substrates. Phosphotyrosine is a central element in cell signaling, and its activity is essential for cellular homeostasis and for appropriate responses to extracellular signals. PTP-1B antagonizes insulin signaling by reducing the activation state of the insulin receptor kinase, thereby inhibiting post-receptor signaling in insulin responsive tissue. The …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 6, Issue 3, 2017 · pp. 21–25 Read article
-
Prevalence and Associated Factors of Attention Deficit Hyperactivity Disorder in School Age Children in Mekelle, Tigray, North Ethiopia, 2017
Abstract: Introduction: Attention-Deficit Hyperactivity Disorder is a neuron developmental disorder. African children are affected with this disorder which rates from 5.4 to 8.7%. This study aimed to assess the prevalence of attention-deficit hyperactivity disorder and its associated factors among school age children at Mekelle city, Tigray, Ethiopia, 2016/17. Method: Cross-sectional survey among 541 children at randomly selected institution was conducted between December 2016 and May 2017. Data were collected using structured …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 7, Issue 2, 2018 · pp. 21–34 Read article
-
Barriers Towards Implementation of Caring, Respectful and Compassionate Healthcare Practice in Tigray Regional State, Ethiopia: A Qualitative Study
Abstract: Background: Patient-centered care is a type of care that is respectful, responsive to the preferences and values of patients. Though policy-makers increasingly adopt systems to enhance person-centred care for patient’s empowerment and improvement of the quality of care, the barriers to implement must be identified continuously so as to give a timely solution. Objective: The aim of this study was to explore barriers towards implementation of caring, respectful and compassionate …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 7, Issue 3, 2018 · pp. 33–38 Read article
-
Virtual Reality Judgment Abilities in Children
Abstract: At younger age children may not be able to decide if a concept is real or not. Eventually with the development of reality judgment skills, the judgment skills are assumed to evolve with age. The study was carried out with the aim of investigating reality judgment abilities in typically developing children between 3–6 years of age. The participants were divided into three groups with a class interval of one year. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 8, Issue 1, 2019 · pp. 25–28 Read article
-
Prevalence of Sexual Violence and Its Associated Factors Among Female Night Time Students of Junior And Secondary Schools in Mekelle City, Northern Ethiopia, 2013
Abstract: Sexual violence refers to any sexual act directed against a person’s sexuality by any person regardless of their relationship to the victim. Sexual violence is prevalent and is a major public health and human rights problem worldwide. The problem is not different from this in Ethiopia. However, lack of data has hindered full understanding and development of appropriate interventions. The objective of the study was to assess the prevalence of …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 4, Issue 2, 2015 · pp. 6–20 Read article
-
An Evaluation of the Efficacy and Safety Profile of Inula Racemosa in Patients of Restrictive Lung Diseases
Abstract: In this paper, we explain the procedure to evaluate the efficacy and safety profile of Inula racemosa in patients of restrictive lung diseases. The patients included in this study were selected from the outpatient clinic of a tertiary care hospital in North India. The present study was initiated on 45 patients suffering from restrictive lung diseases, 31 of these patients were followed up for 6 weeks. Remaining patients did not …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 4, Issue 3, 2015 · pp. 18–21 Read article
-
The Feasibility of Bilateral Tympanoplasty in Single Sitting in Bilateral Chronic Otitis Media
Abstract: Bilateral tympanoplasty is not a routinely performed surgery by otosurgeons. The reason being is the risk of inducing sensorineural deafness and fear of bilateral ear packing post operatively that may render patient’s total deaf. The aim of the study is to assess the feasibility of bilateral tympanoplasty in single sitting in bilateral chronic otitis media. 50 patients with bilateral inactive mucosal type COM underwent bilateral tympanoplasty in same sitting. The …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 4, Issue 3, 2015 · pp. 22–27 Read article
-
Academic Performance and Associated Factors among Students of Mekelle University, College of Health Sciences, 2015
Abstract: Refining students’ educational performance is the crucial element of higher educational institutions and prejudiced by multifactor. Hence, it is important to evaluate the factors affecting little academic accomplishments to address the issue. The objective of this study was to assess the magnitude and factors associated with low academic performance among students at Mekelle University, College of Health Sciences, 2015. Cross-sectional study was conducted among 356 regular undergraduate students at College …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 5, Issue 1, 2016 · pp. 17–21 Read article
-
Evaluation of Postpartum Service Utilization and Causes for Non-Utilization among Governmental EPI Clinic Attendants in Mekelle, Tigray, Ethiopia
Abstract: Maternal and neonatal death is still a major public health problem in Ethiopia. Most of this death occurs during the postnatal period. Evidences shown that, utilization of the recommended postnatal service is very important to reduce the current challenging maternal and neonatal death. Henceforth, the aim of this revision was to assess postnatal crisscross exploitation and its perceived root for non-utilization among governmental EPI health center attendants in Mekelle, Tigray, …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 5, Issue 1, 2016 · pp. 46–51 Read article
-
Determinants of Caesarean Delivery in Ayder Referral Hospital, Mekelle, Tigray, Ethiopia 2015: A Case Control Study
Abstract: Caesarean delivery rates have been increasing around the world from time to time, with current rates in developing countries comparable to other industrialized nations. International concern over such increases has prompted the World Health Organization to suggest that caesarean section rates should not exceed 15%. A study conducted in Ayder Referral Hospital indicated that the rate of caesarean section was 21.90%. The aim of the study was to assess the …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 5, Issue 1, 2016 · pp. 52–59 Read article
-
Magnitude of Perceived Stigma and Factors Associated with Care Givers of Schizophrenic Patients: The Case of Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia
Abstract: Stigma is a social process, experienced and characterized by exclusion, rejection, blaming or devaluation of a person or a group. Schizophrenia, especially because of its distinctive symptoms like common disruptive behavior and perceived dangerousness, exposes patients to stigma and discrimination. If families do not seek help because of stigma, young people will be at risk of longer durations of untreated illness. To assess magnitude and factors associated with perceived stigma …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 5, Issue 2, 2016 · pp. 1–9 Read article