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1978 articles for “phosphoinositol-3-kinase pathway” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Assessment of Nutritional Status and Other Factors Correlates with Academic Performance of Lower Primary School Children from Mekelle, Northern Ethiopia
Abstract: The need to assess the nutritional status of the children who started school is increasing since it has a great effect for their health; and great achievements in their educational career. The overall objective of the research study was to assess the role of nutritional status on the educational performance of lower primary school children from Mekelle, northern Ethiopia. It was conducted from September to May 2015/16. In this study …
Published in Research and Reviews : Journal of Computational Biology · Vol. 6, Issue 2, 2017 · pp. 1–11 Read article
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Voluntary Blood Donation, Future Willingness and Associated Factors Among Attendants of Obstetrics and Gynecology Patients in JIMA University Specialized Hospital, Oromia region, Ethiopia, 2015
Abstract: Background: Hemorrhage is the major cause of maternal death worldwide. This problem is more prevalent in developing countries including Ethiopia. Therefore, availability of adequate blood supply and timely transfusion has paramount importance in reducing maternal deaths. In this aspect, assessing practice, future willingness and associated factors towards voluntary blood donation among attendants can contribute in alleviating the scarcity of blood for transfusion.Objective: To assess voluntary blood donation, future willingness and …
Published in Research and Reviews : Journal of Computational Biology · Vol. 6, Issue 3, 2017 · pp. 1–8 Read article
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A Study on Efficacy of Movement with Mobilization Versus Graded Oscillatory Technique in the Management of Pain and Shoulder Function Among Shoulder Impingement Subjects
Abstract: Many conditions affecting shoulder which includes rotator cuff tear, frozen shoulder, shoulder instability, bursitis and shoulder impingement. Impingement usually refers to compression and mechanical aberration of the rotator cuff tendon, subacromial bursa, or long head of biceps tendon beneath the anterior under surface of the acromion, coracoacromial ligament or under surface of the acromioclavicular joint during elevation of arm. Another possible mechanism of impinge can be attributed to intrinsic breakdown …
Published in Research and Reviews : Journal of Computational Biology · Vol. 6, Issue 3, 2017 · pp. 20–35 Read article
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Practice of Breast Self-Examination and Associated Factors among Female Nurses of Hawassa University Comprehensive and Specialized Hospital, South Ethiopia, 2018
Abstract: Background: Breast cancer is the most commonly diagnosed cancer in women. The aim of this study was to assess practice of breast self-examination and associated factors among nurses. Methods: A hospital based descriptive cross-sectional study was conducted from March to April 2018 on a sample of 180 female nurses. Pretested and structured questionnaire was used to collect the data. Data entry was done using EPI Info 3.5.4 and exported to …
Published in Research and Reviews : Journal of Computational Biology · Vol. 7, Issue 2, 2018 · pp. 23–31 Read article
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Anti-inflammatory Potentials of Various Oxine Compound Series as Cyclooxygenase-2 (COX-2) and Lipoxygenase (LOX) Inhibitors: Induced-Fit Molecular Docking and Pharmacokinetic Prediction Studies
Abstract: The present investigation is an exploration of multiple oxine series in inhibiting crucial anti-inflammatory targets such as cyclooxygenase-2 (COX-2) (PDB ID: 3LN1) and lipoxygenase (LOX) (PDB ID: 1N8Q) by employing the Glide module of Maestro 9.1 software for induced fit docking (IFD). The study also focuses in exploration towards the essential pharmacokinetic parameters (QPlogPo/w, QPlogS, predicted aqueous solubility, QPPCaco, QPPMDCK, and percentage of human oral absorption). The study highlighted the …
Published in Research and Reviews : Journal of Computational Biology · Vol. 7, Issue 3, 2018 · pp. 16–23 Read article
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A Short Review on Role of Nanotechnology in Daily Life
Abstract: Nanotechnology is latest technology of 21st century. It has impacts on each field of life. Below mentioned are various fields in which this technology is playing its positive role. Nanotechnology is predicted to change medicinal services by filling in as a novel technique for disease analysis as well as prevention, quality treatment, drug delivery plus gene therapy. In nanoelectronics, the look for a successor to Complementary metal–oxide–semiconductor (CMOS) innovation is …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 3, 2019 · pp. 24–33 Read article
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Pf Phosphatidylserine decarboxylase: Molecular modeling and inhibithors prediction
Abstract: Plasmodium falciparum (P.f) is a protozoan parasite responsible for the most severe and deadly form of malaria. The resistance of Pf to last resort antimalarial drugs has been reported, there is an urgent need to identify new therapeutic candidates for drug development. Advancements in bioinformatics technologies provide potential cost and time-effective solutions for predicting therapeutic candidates. Phosphatidylserine decarboxylase (PSD) is a member of the lyase family (more specifically, the carboxy-lyases), …
Published in Research and Reviews : Journal of Computational Biology · Vol. 12, Issue 2, 2023 · pp. 60–78 Read article
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Soursop Phytocompounds as Potential Anticancer Agents: A Molecular Docking Study
Abstract: Objective: According to tumor statistics, there will be a total of approximately 1,958,310 new malignancy cases, that balances to nearly 5,370 cases day by day. Without any questions its clearly evident that cancer is considered as one of the deadliest diseases of mankind. The course of this study emphasizes on computational approach for finding new drug for potential target proteins Bcl-2 (4MAN) and Mcl-1(5FDO) by docking against soursop (Annona Muricata …
Published in Research and Reviews : Journal of Computational Biology · Vol. 12, Issue 3, 2023 · pp. 18–39 Read article
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Ramus Condyle Unit Reconstruction Using L-Shaped Ramus Osteotomy in Temporomandibular Joint Ankylosis
Abstract: Aim and Purpose: To evaluate the feasibility of the L-shaped osteotomy in reconstructing the Ramus Condyle Unit (RCU) after gap arthroplasty in patients with temporomandibular joint (TMJ) ankylosis. Objectives: To evaluate the efficacy of the above procedure by evaluating the increase in mouth opening, by assessing the resorption of the newly reconstructed RCU, by assessing any occlusal disturbances, deviation upon mouth opening and obstructive sleep apnoea, caused by decrease in …
Published in Research and Reviews: A Journal of Dentistry · Vol. 9, Issue 1, 2018 · pp. 1–10 Read article
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Retreatodontics in Mandibular First Molar: A Case Report
Abstract: Endodontic retreatment is an integral component of the endodontics which encompasses the efforts to salvage a failing previously endodontically treated tooth. A case is presented of a mandibular first molar which was earlier endodontically treated and during the course of a period; it developed symptoms radiographically and clinically. With patience and effort, required success was achieved. Certainly, restoring a tooth to normalcy enhances the clinician’s confidence in his own skill …
Published in Research and Reviews: A Journal of Dentistry · Vol. 9, Issue 3, 2018 · pp. 34–35 Read article
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Prevalence of Dental Fluorosis in Area of Yemen with Above Optimal Level of Fluoride in Drinking Water: An Exploratory Survey
Abstract: Dental Fluorosis is a developmental defect in enamel formation. It is caused by excessive fluoride intake while teeth are developing; during this period (before teeth erupt) dental tissue is very sensitive to fluoride, typically during a child’s first eight years. The aim of this study is to provide the community with sufficient knowledge about the problem and suggest solutions for prevention from it in future. This study was conducted from …
Published in Research and Reviews: A Journal of Dentistry · Vol. 6, Issue 2, 2015 · pp. 15–25 Read article
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Electromagnetic Fields (EMFs) and Cellular Phones: Controversy over Oral Carcinoma
Abstract: All electrical and electronic devices, anywhere where electricity (electrons) flows through wire, set up magnetic fields (EMFs=low frequency electromagnetic fields). Generation of EMFs occurs when there is any significant flow of electricity. EMFs are alternating fields that center on frequencies up to 300 Hz (radiation in the microwave range). The risk from EMFs occurs from significant exposure from high-voltage power lines or in substation transformers, microwave ovens, cellular phones, appliances …
Published in Research and Reviews: A Journal of Dentistry · Vol. 6, Issue 3, 2015 · pp. 13–17 Read article
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Preventive Dentistry at All Levels of Health Care Services: A Call for Oral Health Care Reform
Abstract: As today’s life expectancy seems to be increased both in developing and developed nations. The major contributor of this success can be of various public health interventions undertaken across the globe. At the same time this achievement brings along many challenges that the health care system, which includes various public health services and public programs should be prepared to face. These challenges include growing burden of chronic illnesses, the rising …
Published in Research and Reviews: A Journal of Dentistry · Vol. 6, Issue 3, 2015 · pp. 36–40 Read article
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The Effect of Magnesium and Zinc Lozenge on Postoperative Sequelae after Third Molar Surgery: A Prospective Randomized, Placebo-Controlled Study
Abstract: Background: The postoperative sequelae after third molar surgery include pain, swelling and trismus, Magnesium has antinociceptive effects that can prevent central sensitization caused by peripheral nociceptive stimulation by blocking the N-methyl-D-aspartate-type glutamate receptors, Zinc acts as anti-inflammatory agent, can promote wound healing, immune system modulation, tissue repair, and significant reduction in the use of analgesics for oral pain. This study was aimed to evaluate the efficacy of Magnesium and Zinc …
Published in Research and Reviews: A Journal of Dentistry · Vol. 12, Issue 2, 2021 · pp. 10–18 Read article
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General Public Opinion and Thinking about Physical Therapy Treatment Strategy: Observational Study
Abstract: Abstract+Background: Physiotherapy means systematic method of assisting cardio-respiratory musculoskeletal-neurological including pain and psychosomatic disease to prevent illness by the way of manual therapy and physical ability. The investigator has found that public frequently confuses the functions of physiotherapists with those of other health professionals. The knowledge regarding physical therapy appears to be inclusive in our country due to lack of evidence based publications. Objectives: To find out the knowledge of …
Published in Research and Reviews: A Journal of Health Professions · Vol. 7, Issue 3, 2017 · pp. 1–8 Read article
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Dietary Habit, Anthropometric Measurements and Haematological Parameters in Correlation with Prevalence of Iron-Deficiency Anaemia among Never Married Tribal Female Postgraduates of Assam, India
Abstract: Iron deficiency (ID) is the most common nutritional deficiency and familiar cause of anaemia worldwide. Among the tribal population of India, the scenario of anaemia is severe. Eating habit along with a number of genetic haemoglobin (Hb) disorders has been found to modify the morbidity and mortality of these populations. Providing information on causes and prevalence rate on anaemia among tribal population in one of the severely affected international border …
Published in Research and Reviews: A Journal of Health Professions · Vol. 8, Issue 2, 2018 · pp. 19–26 Read article
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Risk of Malnutrition and Its Association with Economic Maintenance in Inpatients Older Adults at a University-Affiliated Hospital
Abstract: The demographic aging has led to an increase in the prevalence of malnutrition. Malnutrition risk (MR) is considered as a multifactorial condition associated with an increased morbi-mortality in older adults. The association between MR and socioeconomic factors as the form of economic maintenance (EM) is not yet clear in aged population. However, an effective strategy for the diagnosis of MR is the comprehensive geriatric assessment (CGA). The aim of this …
Published in Research and Reviews: A Journal of Health Professions · Vol. 8, Issue 2, 2018 · pp. 31–36 Read article
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Knowledge on Risk Factors of Pelvic Organ Prolapse and Associated Factors among Mothers attending MCH Clinic, Bansa Daye Primary Hospital, South Ethiopia
Abstract: Background: Pelvic organ prolapse is a main gynaecological problem and admission in developing countries, including Ethiopia. It affects women’s day to day activities and quality of life. This study was conducted to assess knowledge on risk factors of pelvic organ prolapse and associated factors among mothers who attending MCH clinic, at Bansa Daye Primary Hospital, South Ethiopia. Methodology: A facility-based cross-sectional study was conducted from April 1–30, 2018 among 408 …
Published in Research and Reviews: A Journal of Health Professions · Vol. 8, Issue 3, 2018 · pp. 31–36 Read article
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Organ Donation: Awareness and Willingness to Donate an Organ among Basic Nursing and Midwifery Students of a Selected College in Northern Nigeria
Abstract: Background: Organ transplant remains the best option to patient with end stage organ failure (ESOF), incidence of which is rising across the globe along with chronic diseases such as diabetes mellitus, cancers, hypertension amongst others, which are responsible for most cases. With the rise in number of people needing organ transplant, it is lamentable to mention that the rate of organ donation is significantly lower than the demand leading to …
Published in Research and Reviews: A Journal of Health Professions · Vol. 8, Issue 3, 2018 · pp. 37–42 Read article
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Nitric Oxide—An Important Biomolecule in Breast Carcinoma
Abstract: Breast cancer represents significant problem of the world. Reactive nitrogen species of which nitric oxide (NO) is important constituent is a free radical gas which is synthesized by nitric oxide synthase (NOS).NO inhibits DNA synthesis and can damage DNA directly by deamination. In this study, NO level was studied in normal, pre- and postoperative cases of breast carcinoma. For this blood samples from 60 breast carcinoma cases were taken along …
Published in Research and Reviews: A Journal of Health Professions · Vol. 8, Issue 3, 2018 · pp. 55–59 Read article