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1980 articles for “rokitansky’s disease.” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Molecular Docking Studies for the Identification of Mycobacterial Adenosine Triphosphate (ATP) Synthase Inhibitors Using Active Phytocompounds from Plants Curcuma longa, Curcuma zedoaria and Galipea officinalis
Abstract: Objective: Tuberculosis (TB), known in human history for several decades, remains the second leading infectious disease after COVID-19. Still, the occurrence of TB increases due to the bacterium’s greater survival nature. They can survive in extreme conditions by being in long latency and adapting to the host. This study seeks to identify potential inhibitors from Curcuma longa, Curcuma zeodaria, and Galipea officinalis based on ancient folklore and compare them against …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 16–26 Read article
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A Narrative Review on Osteogenesis Imperfecta and Its Management
Abstract: Osteogenesis imperfecta (OI), sometimes referred to as brittle bone disease, is a heterogeneous illness characterized by short stature, several fractures, and distorted bones. The main contributing factor to OI is mutations in the genes needed to produce type 1 collagen. While severe OI is perinatally fatal, mild OI can occasionally not be detected until maturity. The frequency of Osteogenesis imperfecta ranges from about 1:15,000 to 1:20,000 births. Five kinds of …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 1–10 Read article
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Enhancing Image Classification Performance with Deep Neural Networks
Abstract: Classifying images is useful in many domains, including the study of plant diseases and the analysis of human expressions. Image categorization employing the idea of a “deep neural network” helps to compact otherwise cumbersome photos. It is possible to classify images by using the idea of a “deep neural network”. Self-driving cars, medical diagnosis, automatic translation, etc., all make use of Deep Neural Networks. Recently, excellent results have been achieved …
Published in Journal of Telecommunication, Switching Systems and Networks · Vol. 11, Issue 1, 2024 · pp. 13–23 Read article
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Pharmacological Review On Enzalutamide
Abstract: A key therapeutic option in the treatment of prostate cancer, especially metastatic castration-resistant prostate cancer (mCRPC), is Enzalutamide, a second-generation anti androgen drug. Enzalutamide, discovered by Charles Sawyer and Michael Jung at the University of California, Los Angeles, was developed and Food and Drug Administration (FDA)-approved in 2012. Its therapeutic significance was further solidified with subsequent extensions in indications to encompass metastatic castration-sensitive prostate cancer and non-metastatic castration-resistant prostate cancer. …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 7–15 Read article
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Computational Exploration of Bhrijraj-derived Phytochemicals as Potential Anti-inflammatory Agents: A Molecular Docking Study with Cyclooxygenase-II Complex
Abstract: The molecular docking analysis was meticulously conducted using state-of-the-art computational tools, notably Chimera and Python. These tools were employed to unravel the complex interactions between the identified phytochemicals from Bhrijraj and the target protein, COX-II. The 3D structures of the phytochemicals were prepared with precision using ChemSketch, ensuring accuracy in the subsequent molecular docking simulations. This rigorous approach enhances the reliability and validity of the findings. This research aims to …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 31–37 Read article
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Review on Solid waste management and treatment technology
Abstract: Solid waste management is increasingly critical in safeguarding public health, the environment, and natural resources. Contaminated food, water, soil, and air from various environmental matrices pose health risks, highlighting waste as a significant topic on the European Environment and Health Agenda. Managing and disposing of hazardous waste is a global concern, with anthropogenic sources such as industrial operations and domestic and agricultural waste contaminating numerous natural resources. Public concern over …
Published in Journal of Petroleum Engineering & Technology · Vol. 14, Issue 1, 2024 · pp. 31–35 Read article
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Topical Luliconazole for the Management of Fungal Infections: A Review
Abstract: Luliconazole, an antifungal agent of the imidazole class, possesses a distinctive structure where the imidazole component is fused with the ketene dithioacetate configuration. It exists in its R-enantiomer form, which exhibits greater antifungal efficacy compared to lanoconazole, a compound comprising a racemic blend. Strong action is shown by luliconazole against filamentous fungi, such as dermatophytes. The pharmacokinetic characteristics of dermatophytes, such as Trichophyton rubrum and Microsporum gypseum, help explain why …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 1–6 Read article
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Insilico Structural Analysis and Homology Modeling of Crustin Protein from Fiddler Crab Species
Abstract: In terms of biomass and ecological or economic importance, the crustacea are the largest, most noticeable, and possibly, the most significance group of marine or aquatic arthropods. Because of their enormous commercial value and the necessity to prevent disease outbreaks in the shellfish aquaculture industry, decapods are the experimental animals of choice for practically all biological studies involving immune responses. Antimicrobial host-defense peptides (AMPs) are major components of metazoan immunity, …
Published in International Journal of Cheminformatics · Vol. 1, Issue 1, 2023 · pp. 1–7 Read article
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Chemical Preparation Methods of Nano Material with their Applications
Abstract: Scientists were not satisfied with the diagnosis, exploration, injection and imaging through modern medical nanotechnology, but they were also able through this technology to activate smart microscopic bombs that target the cancer cell and detonate it, killing the cancer cells. This technology was tested on laboratory mice and achieved great success. Nanotechnology is the technology of the future, not only in the medical and therapeutic aspect, but also in everything …
Published in Journal of Petroleum Engineering & Technology · Vol. 14, Issue 2, 2024 · pp. 1–9 Read article
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Chemical Preparation Methods of Nano Material with their Applications
Abstract: Scientists were not satisfied with the diagnosis, exploration, injection and imaging through modern medical nanotechnology, but they were also able through this technology to activate smart microscopic bombs that target the cancer cell and detonate it, killing the cancer cells. This technology was tested on laboratory mice and achieved great success. Nanotechnology is the technology of the future, not only in the medical and therapeutic aspect, but also in everything …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 2, 2024 · pp. 1–9 Read article
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Fields of Data: Exploring AI’s Impact on Modern Farming
Abstract: The Food and Agriculture Organization (FAO) of the United Nations projects that by 2050, there will be a further 2 billion people on the planet, but just 4% of that additional land will be used for agriculture. Under such circumstances, the most recent technical developments and solutions to the farming industry’s obstacles can be used to achieve more effective farming methods. The direct implementation of machine intelligence or artificial intelligence …
Published in International Journal of Solid State Innovations & Research · Vol. 1, Issue 2, 2023 · pp. 14–20 Read article
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Revolutionizing Diabetes Management: Nanostructured Biosensors for Real-time Monitoring
Abstract: Chronic metabolic disease known as diabetes mellitus, which is characterized by dysregulated blood glucose levels, is becoming a major global health concern. The implementation of automated insulin administration systems and continuous glucose monitoring (CGM) has shown promise in the management of diabetes. Nanostructured biosensors, leveraging the unique properties of nanomaterials, offer enhanced sensitivity, selectivity, and biocompatibility, making them ideal candidates for real-time monitoring and personalized treatment. This article delves into …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 14, Issue 1, 2024 · pp. 49–70 Read article
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Epidemiology and Mycological Analysis of Superficial Mycosis in a Northern Indian Tertiary Care Hospital
Abstract: Background: A fungal infection that affects the outer layer of the skin and its connective tissue, including hair and nails, is called superficial mycosis. These infections are typically caused by fungi, which thrive on keratin, the proteinthat makes up the nails, hair, and skin. A common disease that can affect people of any age, gender, or race is superficial mycosis. Usually, it appears as a streaky red rash that can …
Published in International Journal of Fungi · Vol. 1, Issue 1, 2024 · pp. 1–12 Read article
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Farming Forward: Integrating IoT, AI, and Image Processing for Sustainable Agriculture
Abstract: Farming Forward: Integrating IoT, AI, and Image Processing for Sustainable Agriculture" explores the convergence of cutting-edge technologies in revolutionizing traditional farming practices towards sustainability. This study investigates the integration of Internet of Things (IoT), Artificial Intelligence (AI), and Image Processing techniques in agricultural contexts, aiming to enhance efficiency, productivity, and environmental stewardship. Through a comprehensive review of recent advancements and case studies, this research elucidates the transformative potential of IoT-enabled …
Published in Journal of Communication Engineering & Systems · Vol. 14, Issue 2, 2024 · pp. 52–69 Read article
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Honeybees as pollinators and their conservation: A review
Abstract: Pollination is a critical mechanism for maintaining and conserving biodiversity, with pollinator diversity playing a major role for the enhancement of food security and livelihoods. Pollinators provide the essential service of enabling plants to produce fruits and seeds in our ecosystems. These pollinators come from many groups within the kingdom Animala, including insects, birds, bats and reptiles. Among them, arthropods, especially honey bees, are pivotal In delivering pollination services to …
Published in International Journal of Insects · Vol. 1, Issue 1, 2024 · pp. 7–11 Read article
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Current Drugs Target the EGFR
Abstract: Cancer is a devastating disease, but there have recently been significant advancements in therapy that have identified EGFR and its related proteins as valuable indicators and targets for treatment. The ERBB receptor tyrosine kinase superfamily includes EGFR, which is a transmembrane glycoprotein. When the EGFR receptor interacts to its particular ligand, EGF, it causes tyrosine residues to be phosphorylated and forms receptor dimers with other members of the receptor family. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 1–8 Read article
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The Induction, Formation, and Establishment of Giant Cell in Plant-Parasitic (Meloidogyne Spp.)-Host Interactions: A Molecular and Cellular Basis
Abstract: Root-knot nematodes, (RKN) are obligatory endoparasites of over 3000 plant species, causing $70 billion in annual economic losses globally. The second stage juveniles hatch from the eggs invade the root apex and inject pathogen effectors that induce specialized feeding cell called Giants cell that are large multinucleated cell formed, due to repeated cycles of mitosis without cytokinesis and served sole source of feeding site for rootknot nematode. The ability RNN …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 2, 2024 · pp. 34–45 Read article
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Exploring Diabetic Retinopathy from an Ayurvedic Lens: Insights Leveraging Bioinformatics
Abstract: Diabetic retinopathy is one among the target diseases for VISION 2025. The huge cost required for treatment, economic loss due to absenteeism from work etc... has made it as a great public challenge. Therefore it is in need of the hour to address the issues of diabetes mellitus with its complication Diabetic Retinopathy with all seriousness and it is quite essential to search for a affordable medical care for the …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 2, 2024 · pp. 45–51 Read article
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Extraction and Compound Analysis of Bauhinia acuminata: Soxhlet Method and Identification
Abstract: In the present study, the extraction and compound analysis of Bauhinia acuminata using the Soxhlet method, coupled with identification techniques, were conducted. Bauhinia acuminata L., a member of the Leguminosae (Fabaceae) family in the Caesalpinioideae subfamily, is a shrub usually reaching a height of around 3 m. It is native to tropical Southeast Asia and commonly found in the tropical regions of India and China. Primarily grown for ornamental purposes, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 2, 2024 · pp. 18–23 Read article
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The Economic Essence of Ayurveda
Abstract: According to Hindu mythology, Lord Dhanwantari was created with nectar during sea churning means Samudra Manthan. He is regarded as the ruler of medicine. Following that, Ashwani Kumar, Lord Sun's son, was regarded as a medical science conservative. In the reference of different Sanskrit literature and in Ram Charit Manas, Sri Tulsi Das described about formation of human body. He used five essential ingredients to describe the creation of human …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2024 · pp. 39–47 Read article