Search
154 articles for “PKA/CREB pathway”
Nothing matched all of your words, so these match any of them.
-
Steel Structural and Functional Characteristics Focusing on Corrosion Mechanisms
Abstract: This research article examines steel structural and functional characteristics, focusing on corrosion mechanisms and inhibitor protection strategies. Steel corrosion affects numerous industries, causing significant economic losses and safety risks. Fundamental electrochemical processes behind various corrosion forms including uniform, pitting, crevice, galvanic, intergranular, and stress-induced corrosion are explained. The chapter highlights the steel industry's importance while investigating how corrosion impacts performance and longevity. Protection methods discussed include material selection, environmental modification, …
Published in International Journal of Minerals · Vol. 2, Issue 2, 2025 · pp. 25–34 Read article
-
Persistent Atmospheric and Ecosystem Impacts of Enteric Methane Emissions from Intensive Livestock Production Systems
Abstract: Enteric methane emissions from intensive livestock production systems exert a significant long-lasting influence on atmospheric stability and ecosystem integrity. Recent observations confirm that global methane emissions continued to rise through the early 2020s, with total emissions exceeding 620 teragrams per year by 2024, driven by expanding ruminant production and associated feed systems. Anthropogenic sources accounted for more than 330 teragrams per year, reflecting sustained growth in agricultural and fossil fuel …
Published in International Journal of Atmosphere · Vol. 2, Issue 2, 2025 · pp. 18–38 Read article
-
Recent Advancements and Current Status of Hydrogen Fuel Cells: Materials, Systems, Applications, and Commercialization Prospects
Abstract: In the transportation, stationary electricity, and industrial sectors, hydrogen fuel cells have become a crucial clean-energy technology that can help achieve worldwide decarbonization. Significant progress has been made in catalyst design, membrane engineering, stack architecture, system optimization, and hydrogen generation pathways throughout the last ten years (2018–2025). Platinum group metal (PGM) loading has been significantly reduced, single-atom and transition-metal-nitrogen-carbon (M-N-C) catalysts for oxygen reduction have been developed (Wu et al., …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 3, Issue 2, 2025 · pp. 6–24 Read article
-
Assessment of Matrix Cracking and Fiber Breakage in Hybrid Composite Materials.
Abstract: Hybrid composite materials, combining two or more distinct fiber or matrix constituents, have emerged as advanced structural solutions for aerospace, automotive, marine, and civil engineering applications. However, their complex microstructure makes them susceptible to multiple interacting damage mechanisms, particularly matrix cracking and fiber breakage. This study provides a comprehensive assessment of these damage modes, emphasizing their initiation, evolution, and combined effects on the mechanical integrity of hybrid composites. Matrix cracking …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 3, Issue 2, 2025 · pp. 1–5 Read article
-
Spintronic Logic Circuits for Ultrafast Processing
Abstract: Spintronic logic has emerged as one of the most promising post-CMOS paradigms capable of addressing the speed, density, and energy challenges of deeply scaled silicon technologies. By relying on the intrinsic properties of electron spin and magnetization dynamics, spintronic devices—particularly Magnetic Tunnel Junctions (MTJs), Spin-Transfer Torque (STT), and Spin–Orbit Torque (SOT) structures—enable ultrafast, non-volatile data processing with significantly reduced energy consumption. Despite remarkable device-level advancements, circuit- level realization of high-speed, …
Published in International Journal of VLSI Circuit Design & Technology · Vol. 3, Issue 2, 2025 · pp. 35–43 Read article
-
Digital Frontiers in Life Sciences: The Transformative Role of Computing in Modern Biology
Abstract: The integration of computers in the biological sciences has revolutionized research and experimentation, facilitating advancements in areas such as genomics, bioinformatics, systems biology, and ecological modeling. The ability to process vast amounts of biological data efficiently has transformed how scientists study complex biological systems and phenomena. Computational tools enable the analysis of DNA sequences, protein structures, metabolic pathways, and ecological dynamics, which were previously beyond the reach of traditional laboratory …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 1, 2026 Read article
-
Interaction of Mosquito’s hppd Enzyme with Lansoprazole Sulfide A New Hope to Tackle the Mosquito Menace – an in-Silico Study
Abstract: Tyrosine detoxification is an important physiological process that helps blood-feeding insects, such as mosquitoes that transmit Plasmodium parasites causing malaria, digest their blood meals. An enzyme known as 4-hydroxyphenylpyruvate dioxygenase (HPPD), which is part of the tyrosine detoxification pathway, helps in removing excess tyrosine in a high-protein blood meal. Excess tyrosine can be lethal to the insects, and hence, the role of HPPD enzyme is very critical. Inhibitors of HPPD …
Published in International Journal of Insects · Vol. 3, Issue 1, 2026 · pp. 1–11 Read article
-
Paternal Pre-Pubertal Smoking: Small RNAs, Lasting Marks, and the Hidden Legacy of Early Exposure
Abstract: While the negative effects of maternal smoking during pregnancy are well-established, the lasting and transgenerational impact of paternal pre-pubertal smoking remains a critical, underexplored area. Emerging evidence in sperm epigenetics suggests that cigarette exposure during early male development may create persistent molecular imprints that can affect the health of future offspring. This phenomenon is rooted in the fact that heredity extends beyond the DNA sequence. Sperm carry a complex epigenetic …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 1–5 Read article
-
Nutrition Induced Gut Microbiota Modulation in Food Animals: Implications for Viral Susceptibility, Shedding and Transmission Dynamics for Sustainable Development
Abstract: The gut microbiota has emerged as a central mediator linking host nutrition, immune competence, and vulnerability to viral pathogens in food animals. Diet is a primary driver of microbial community structure and function, influencing metabolite production, intestinal barrier integrity, and systemic antiviral immunity. Accumulating evidence indicates that nutrition induced modulation of the gut microbiota can substantially alter viral susceptibility, replication, and shedding patterns, with downstream effects on transmission dynamics within …
Published in International Journal of Virus Studies · Vol. 3, Issue 1, 2026 · pp. 46–56 Read article
-
Recent Trends in Heavy Metal Pollution of Groundwater: A Review
Abstract: Heavy metal pollution in groundwater has emerged as a major environmental and public health concern worldwide due to its persistence, toxicity, and potential for bioaccumulation. Rapid industrialisation, urban expansion, intensive agriculture, mining activities, and improper waste disposal have significantly increased the release of heavy metals into subsurface environments. Groundwater, being a primary source of drinking water in many regions, is particularly vulnerable to contamination, posing serious risks to human health …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 4, Issue 1, 2026 · pp. 14–24 Read article
-
Unfolding the Awareness for Women and Children in Vidarbha Region
Abstract: The concept of “Roots and Wings” as a pathway to empower women and children in Vidarbha region, focusing on the need for both a strong foundation and the freedom to thrive. “Roots” symbolize support systems like education, cultural identity, and community care, while “wings” represent opportunities for growth, self-expression, and independence. Women in Vidarbha often face deep-rooted challenges, including gender inequality, domestic violence, menstrual health, abuse and a lack of …
Published in International Journal of Trends in Humanities · Vol. 2, Issue 2, 2025 · pp. 39–45 Read article
-
Gut Microbial Metabolites in Inflammatory, Metabolic, and Neurologic Disorders.
Abstract: The human gut microbiota transforms dietary and hostderived substrates into a diverse array of metabolites—including shortchain fatty acids (SCFAs), hydrogen sulfide (H₂S), bile acid derivatives, indoles, trimethylamine Noxide (TMAO), branchedchain amino acid (BCAA) derivatives, and lipopolysaccharide (LPS)—that act as key signaling mediators along epithelial, immune, endocrine, and neural axes. These metabolites regulate barrier integrity, energy homeostasis, inflammation, and gut–brain communication and are increasingly implicated in the pathogenesis of inflammatory bowel …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 58–64 Read article
-
Artificial Intelligence in Entomology: Global Advances, Applications, and Future Directions in Insect Research and Pest Management
Abstract: Artificial Intelligence (AI) is transforming entomology by enabling scalable, data-driven approaches to insect identification, ecological monitoring, and sustainable pest management. This review synthesizes recent global advances in AI applications across taxonomy, behavioral ecology, predictive modeling, and precision agriculture. Machine learning and deep learning techniques—including convolutional neural networks, acoustic classification models, and ensemble predictive algorithms—have demonstrated high classification accuracies (often exceeding 90% under controlled conditions) and improved early detection of pest …
Published in International Journal of Insects · Vol. 3, Issue 1, 2026 · pp. 29–40 Read article
-
Marine Fungi – An Expandable Source for Production of Novel Bioactive Metabolites: A Comprehensive Review
Abstract: The marine environment, representing the largest and most extreme biome on Earth, serves as an unparalleled reservoir of biodiversity. Within this vast ecosystem, marine fungi have emerged as a prolific source of structurally diverse and pharmacologically active secondary metabolites. Dwelling in habitats characterized by extreme high salinity, high hydrostatic pressure, and low temperatures, these microorganisms have evolved unique biochemical and metabolic pathways to synthesize novel compounds, including pyrrole-imidazole alkaloids, cyclic …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 30–37 Read article
-
Bridging the Gap Between Product Development and Entrepreneurship in Engineering Curriculum: A Framework-Based Approach Aligned with NEP 2020
Abstract: Despite advancements in technical education, Indian engineering graduates frequently enter the workforce lacking critical competencies in product development (PD) and entrepreneurship. This imbalance has drawn scrutiny from industry and policymakers alike, with national directives such as the National Education Policy (NEP 2020) emphasizing a shift toward “experiential, holistic, integrated and inquiry-driven” learning models. Similarly, the All-India Council for Technical Education (AICTE) has embedded innovation labs, internship mandates and entrepreneurship courses …
Published in International Journal of Education Sciences · Vol. 3, Issue 1, 2026 · pp. 87–100 Read article
-
Marine Microbial Ecology: A Comprehensive Review of Interactions, Symbiosis, and Bioprospecting.
Abstract: Marine microorganisms constitute the largest and most dynamic fraction of Earth's biodiversity, governing vital ecosystem functions ranging from global biogeochemical cycling to host-specific symbiotic associations. This review provides a comprehensive synthesis of the complex interaction networks within marine microbial communities. We first explore the theoretical foundations of microbial niche construction and evolutionary dynamics in the ocean. Subsequent sections dissect micro-scale interactions within the phycosphere, where chemical gradients dictate cross-kingdom mutualisms …
Published in International Journal of Marine Life · Vol. 3, Issue 1, 2026 · pp. 6–16 Read article
-
Mapping A Contextualized Southern Africa's Innovation Ecosystem: The Emerging Role of Higher Education in Promoting Inclusive Innovation and Rural Industrialization
Abstract: Higher education institutions (HEIs) are increasingly recognized as strategic actors in shaping innovation ecosystems that can respond to persistent socio-economic inequalities in the Global South. In Southern Africa, where rural underdevelopment, youth unemployment, weak industrial bases, and uneven innovation capacities remain pressing concerns, universities are under growing pressure to move beyond their traditional teaching and research mandates and contribute more directly to inclusive development. This paper examines the emerging role …
Published in International Journal of Rural and Regional Development · Vol. 4, Issue 1, 2026 · pp. 14–27 Read article
-
Sustainable Architecture for Rural Communities: The Tanzanian Family House Model
Abstract: Sustainable rural housing in East Africa must respond simultaneously to climatic stress, water scarcity, sanitation challenges, and socio-cultural practices. This article presents the Tanzanian Family House as a climate-responsive and resource-efficient housing model developed specifically for rural Tanzanian communities. The project integrates low embodied energy materials, passive environmental strategies, and decentralized infrastructure systems to create a durable and culturally grounded dwelling that can be constructed using local skills and materials. …
Published in International Journal of Rural and Regional Development · Vol. 4, Issue 1, 2026 · pp. 1–12 Read article
-
Atmospheric Determinants of Feed, Fodder, and Forage Contamination in a Changing Climate: Emerging Challenges for Sustainable Livestock Production
Abstract: Feed, fodder, and forage contamination represents a growing constraint to sustainable livestock production under a changing climate. Atmospheric determinants such as rising temperature, altered precipitation patterns, increased humidity, elevated carbon dioxide concentration, and enhanced aerosol and pollutant loads are increasingly recognized as critical drivers of contamination risks across feed supply chains. These atmospheric factors directly and indirectly influence crop growth, fungal proliferation, mycotoxin biosynthesis, microbial survival, and the deposition of …
Published in International Journal of Atmosphere · Vol. 3, Issue 1, 2026 · pp. 1–14 Read article
-
Early Life Nutrition as a Determinant of Long-Term Vaccine Immunogenicity in Livestock: Mechanisms, Practical Strategies, and Species-Specific Considerations
Abstract: Early life represents a critical period for immune system development in livestock, during which nutritional exposures can exert long lasting effects on vaccine immunogenicity. Although vaccination is a cornerstone of infectious disease control in food producing animals, marked variability in vaccine induced immune responses is frequently observed under commercial conditions. Growing evidence suggests that this variability is partly driven by differences in early nutritional status, which can influence immune maturation, …
Published in International Journal of Vaccines · Vol. 3, Issue 1, 2026 · pp. 15–26 Read article