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105 articles for “preservation”
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The Renaissance and Resilience of CB1 Reverse Agonists: From Central Liabilities to Peripheral Promise
Abstract: Building upon these foundational insights, current research has increasingly focused on refining the pharmacological profile of CB1 reverse agonists to maximize therapeutic benefit while minimizing central adverse effects. The adverse neuropsychiatric outcomes associated with first-generation agents such as Rimonabant including anxiety, depression, and suicidal ideation highlighted the critical role of central CB1 receptors in mood regulation. Consequently, drug development strategies have shifted toward peripherally restricted CB1 reverse agonists that exhibit …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 30–35 Read article
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Innovations in Mineral Science and Engineering for Sustainable Resource Development
Abstract: The growing global demand for mineral resources, coupled with increasing environmental and social concerns, has intensified the need for sustainable approaches in mineral science and engineering. Traditional mining and mineral processing practices, while essential for industrial development, are often associated with high energy consumption, resource depletion, and environmental degradation. In response, recent innovations in mineral science and engineering have focused on improving resource efficiency, minimizing environmental impact, and ensuring long-term …
Published in International Journal of Minerals · Vol. 3, Issue 1, 2026 · pp. 31–36 Read article
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Circadian Regulation of Lipid Peroxidation in the Brain: Linking Ferroptosis to Neurodegenerative Vulnerability
Abstract: The human brain operates through highly coordinated physiological and biochemical processes that regulate cognition, behavior, and neural adaptability. Central to these processes are mechanisms governing brain function, neurophysiology, and neuroplasticity, which are increasingly recognized to be influenced by circadian rhythms. Recent advances in cognitive neuroscience, neuroimaging, and behavioral neuroscience have revealed that disruptions in circadian regulation can significantly impact oxidative balance within the brain, particularly through enhanced lipid peroxidation. Lipid …
Published in International Journal of Brain Sciences · Vol. 3, Issue 2, 2026 · pp. 1–14 Read article
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Emerging Trends in Photobiology: Exploring the Photophysics and Photobiology of the Eye
Abstract: The eye consists of three main segments: the cornea, lens, and retina. The primary function of the anterior ocular tissue, the cornea and lens, is to transmit and focus light onto the retina without distortion. They also filter UV light (under 400 nm), preventing it from reaching the retina. While light reaching the retina is mostly used for vision, it can also have various effects on the eye's constituents, both …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 3, Issue 1, 2025 · pp. 31–37 Read article
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Nutraceuticals & their classification: A Review
Abstract: The combination of "nutrition" and "pharmaceutical" is called nutraceutical. Nutraceuticals, in general, are foods or dietary components that significantly contribute to changing and preserving normal physiological function, which keeps people healthy. Nutraceuticals can be classified into various categories on the basis of their composition and mechanism of action. Nutraceuticals are food items that contain dietary fibre (DF), probiotics, prebiotics, polyunsaturated fatty acids (PUFA), antioxidants, and other herbal natural foods. These …
Published in International Journal of Land · Vol. 1, Issue 1, 2024 · pp. 11–17 Read article