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114 articles for “hematological”
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Oral Manifestations of Haematological Disorders (RBC Disorders)
Abstract: Haematological abnormalities are diverse in nature, in its causation as well as in its clinical manifestations, most ofwhich are exhibitedin the oral cavity. In fact,the oral site in many instances could act as the forerunner of itsmanifestations before the expression of systemic signs and symptoms. The symptoms of haematological disorders are sovaried and nonspecific but often represent the initial sign of an underlying disease. Anaemic disorders are associated with orofacial …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 1, 2020 · pp. 18–22 Read article
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An Investigation of Paget Disease for Finding Epithelium in the Cell Tissue for Breast and Nipple Eczema
Abstract: Breast disease is a type of cancer that can manifest externally as eczema with changes in the skin surrounding breast nipple. Sir James Paget identified this disease for the first time in 1874 as a rare condition responsible for 1–4.3% of all breast cancers. The disease also seems benign in it, confined to the skin and is sometimes ignored even if it indicates a symptom of latent breast cancer. Paget's …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 1, 2020 · pp. 23–28 Read article
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Iron Deficiency Anemia: From Historical Background to Management—A Review
Abstract: The word anemia comes from the ancient Greek word άναιμία, anaimia, meaning ‘lack of blood’. Simply, anemia means a decrease in the total amount of hemoglobin (Hb) or the number of red blood cells (RBCs). Anemia remains a widespread public health problem with major consequences on human health as well as social and economic development. Globally, the most significant contributor to the onset of anemia is iron deficiency (ID) so …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 1, 2020 · pp. 29–40 Read article
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Effectiveness of Structured Teaching Programme on Knowledge Regarding Postmenopausal Bleeding and Early Detection of Endometrial Cancer Among Postmenopausal Women Residing in Selected Area
Abstract: The present study was aimed to assess the effectiveness of structured teaching programme (STP) on knowledge regarding postmenopausal bleeding (PMB) and early detection of endometrial cancer among postmenopausal women in the selected area. In view of the nature of the problem under study and to accomplish the objectives of the study, evaluative approach was found to be appropriate to describe the knowledge of postmenopausal women regarding PMB and early detection …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 1, 2020 · pp. 41–46 Read article
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Rectal Polyp may turn out to be Rectal Adenocarcinoma—Case Report Emphasize Histopathology as a Routine Measure
Abstract: AbstractAdenocarcinoma is a commonest type of colorectal cancer. For the primary care physicians, a review of the pathophysiology and clinical presentation are important in its diagnosis. In India the annual incidence rate of rectal cancer in men is 4.1 per 100000 populations. Colon cancer in women is 3.9 per 100000 populations. Causes of colorectal cancer include genetic and environmental factors or lifestyle-related factors. Some previous studies confirm colonoscopy as a …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 2, 2020 · pp. 19–23 Read article
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Current Tumour Immunotherapy strategies and their molecular basis
Abstract: AbstractStudying cancer and devising techniques to combat the deadly disease has witnessed a paradigm shift, from conventional toxic treatments of radiation and chemotherapy, to a more specific, and biologically significant immunotherapy and molecular targeted therapy. This can be seen in the global immunotherapy market, which is dominated by North America region valued about $45.9 billion in 2017 that is estimated to reach about $115.9 billion by 2025, and is closely …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 2, 2020 · pp. 1–18 Read article
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Principles of Interpolating Prognostication in Oncology
Abstract: AbstractThe precise prediction in oncology plays a critical role in prevention, treatment, assessment of the effectiveness of methods of treatment and treatment outcomes for cancer patients. Some medical researches claim that statistical processing (factor analysis) permits to precisely individualize the prognosis, which determines the possibility of an individual approach to monitoring and postoperative treatment of patients. However, factor analysis permits only creating a matrix of factors that can significantly describe …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 2, 2020 · pp. 39–51 Read article
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Discovery of Curcumin: Miraculous Activity as Anticancer
Abstract: AbstractCancer is the second most life-threatening disease and one of the main public health problems worldwide now a day. Despite the great advances in cancer therapy, the incidence and mortality rates of cancer remain high. Therefore, the quest for more efficient and less toxic cancer treatment strategies is still at the forefront of current research. Curcumin is an active ingredient of the Curcuma longa plant, has received great attention over …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 2, 2020 · pp. 29–38 Read article
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Human Arginase I (Arg I)—A Potential Broad-spectrum Anti-cancer Agent: Perspectives and the Road Ahead
Abstract: Cancer is the second leading cause of morbidity and mortality globally. A variety of effective regimens are available for the treatment of different cancers, however, there is still a need for the development of safe and effective broad-spectrum anti-cancer agent(s). Towards this, amino acid-depleting enzymes have proven to be effective in the treatment of certain auxotrophic cancers. In this review, we have briefly discussed arginine metabolism and arginine depletion as …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 3, 2020 · pp. 23–35 Read article
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A Literature Review on Future Perspective of Metformin use for Chemotherapy
Abstract: The emergence of metformin as a potential anticancer and cancer-preventive therapeutic tool is exciting. More recently, metformin has been associated with decreased cancer incidence and mortality in diabetic patients and the insulin-lowering effects of metformin are integral to its anticancer properties. With the added benefits of being readily available, economical, and easily tolerated with good safety profile, it can be effortlessly transitioned from bench to bedside for cancer therapy. So, …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 3, 2020 · pp. 1–9 Read article
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To Develop Self-instructional Module on ‘Umbilical Cord Stem Cell Collection, Preservation and Utilization’ and Evaluate its Effectiveness on Improving the Knowledge of Operational Level Nurses
Abstract: Umbilical cord stem cell based regenerative and cellular medicine has now become a fascination for all. The umbilical cord blood, donated by mothers after the birth of newborn, has become an accepted source of hematopoietic stem cells for bone marrow reconstitution. They play an important role in the treatment of blood and immune system related genetic diseases, cancers, and blood disorders. This study is aimed to assess the knowledge of …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 3, 2020 · pp. 10–22 Read article
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Nitrosamine: The Carcinogenic Impurity in Angiotensin Receptor Blockers
Abstract: Angiotensin II Receptor Blockers (ARBs), commonly known as the Sartans, are used in the treatment of hypertension for a long time. Currently, seven Sartan drugs, i.e. Valsartan, Losartan, Candesartan, Irbesartan, Telmisartan, Olmesartan, and Eprosartan, are in use. Recently, Nitroso impurity was detected in Valsartan active pharmaceutical ingredient, which led to the recall of batches of products containing it. Even in trace amounts, the impurity is said to be a probable …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 3, 2020 · pp. 36–43 Read article
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The Effect of the 632.8 nm Laser Blood Irradiation on PASI, TC and TG in Patients with Psoriasis Vulgaris
Abstract: Objectives: The aim of this study is to study the effect of the 632.8nm laser blood irradiation (LBI) on PASI, TC and TG in patients with psoriasis vulgaris. Patients and methods: A total of 90 cases of psoriasis vulgaris were divided into 3 groups according to the paths of laser irradiation: Intravenous Laser Blood Irradiation (ILBI: A Group), nasal mucous irradiation (B Group), no irradiation (C Group). All patients were …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 3, 2020 · pp. 44–46 Read article
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Assessment of Knowledge and Attitude of Sudanese Oncology Residents Regarding Osteonecrosis of the Jaws for Patients Receiving Radiotherapy and/or Chemotherapy
Abstract: AbstractBackground: Cancer patients in the Sudan present usually in advanced stages. Radio and/or chemotherapy had a significant role in the treatment of cancer. Osteonecrosis of the jaws secondary to radiotherapy and/or chemotherapy is considered a serious complication which needs careful handling as it affects the quality of life. Objective: The present study aimed to assess the knowledge and attitude of oncology residents regarding osteonecrosis of the jaws of patients receiving …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 11, Issue 3, 2022 · pp. 1–10 Read article