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109 articles for “Biologic Therapies”
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Artificial Intelligence in Healthcare for Implants and Tissue Regeneration: Advances, Challenges, and Future Directions
Abstract: Artificial intelligence (AI) has been a revolutionary influence in contemporary healthcare, especially in implant design, biomaterials research, and tissue regeneration. In regenerative medicine, AI facilitates predictive modeling, optimization, and decision-making via the analysis of intricate biological, material, and clinical information. This study analyzes current research on AI applications in implant technologies and tissue regeneration, specifically addressing scaffold engineering, biomaterial characterisation, stem cell and gene treatments, smart biomaterials, and implant planning. …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 13, Issue 3, 2025 Read article
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NanoBioAI: Utilizing Python to Investigate Magnetocaloric Effects in Magnetotactic Bacteria and Optimized Conditions for Thermotherapy
Abstract: The study presented in the research work represents a multidisciplinary approach, integrating biology, nanotechnology, and artificial intelligence. It specifically highlights the use of python computational power to investigate magnetocaloric effect (MCE) in magnetotactic bacteria (MTB), a phenomenon yet to be fully understood, characterized by reversible heating and cooling effects induced by magnetic fields. MTB are unique in that they contain embedded magnetic nanoparticles ranging from 10–100 nm in diameters. These …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 11, Issue 2, 2024 · pp. 122–131 Read article
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Cardiovascular Modeling with Computational and Mathematical Methods
Abstract: The cardiovascular system, a complex network responsible for delivering life-sustaining oxygen and nutrients throughout the body, is a prime target for advanced understanding and improved therapies. Due to the inherent difficulties in directly observing internal physiological processes and the complexities of interactions within the system, computational and mathematical modeling have emerged as powerful tools in cardiovascular research. This article explores the significance of these methods in unveiling the heart's secrets …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 2, 2025 · pp. 11–21 Read article
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Medically Important Hemiptera: Bed Bugs and Kissing Bugs in Human Health.
Abstract: Bed bugs (family Cimicidae) and kissing bugs (subfamily Triatominae) are hematophagous Hemiptera of major medical importance, yet they differ markedly in their public health impact. Bed bugs have resurged globally over the past three decades, with infestations reported from homes, multi-unit housing, hotels, transportation, and healthcare facilities in both high and low-income settings. They are not established biological vectors of human pathogens, but their bites cause pruritic papules, urticarial, and …
Published in International Journal of Insects · Vol. 3, Issue 1, 2026 · pp. 41–49 Read article
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CRISPR-Cas9: Revolutionizing the Genetic Frontier
Abstract: The rapid development of CRISPR/CRISPR-associated enzyme (Cas) technology has enabled truly customised treatment of human genetic disorders, paving the way for recent developments in the field of gene therapy. Because CRISPR/Cas can accurately target and edit individual genes within a genome, it has established itself as a formidable tool for genetic manipulation. CRISPR/Cas9 technology allows for precise editing of specific DNA sequences in an organism's genome. This method uses three …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 Read article
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Indirect Treatment Comparison in Meta-Analysis Using Three Methods for Rheumatoid Arthritis
Abstract: Background: The data were extracted from the comparative effectiveness review (CER) on pharmacological treatments for rheumatoid arthritis (RA) developed by the International University of North Carolina Evidence Based Practice Center (UNC EPC). The included studies enrolled patients with active RA despite oral disease-modifying antirheumatic drugs (DMARD) therapy. The outcome measures of choice were American College of Rheumatology (ACR) 20/50/70 response rates.Objective: To compare and find the best treatment for RA …
Published in Research and Reviews : Journal of Computational Biology · Vol. 7, Issue 1, 2018 · pp. 22–27 Read article
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Epigenetic Modifications in Health, Disease, and Precision Therapeutics (From Genome to Epigenome)
Abstract: Introduction: Epigenetic alterations play a crucial role in regulating gene expression in both normal physiological and disease states. These reversible modifications—such as DNA methylation, histone acetylation, phosphorylation, ubiquitination, and chromatin remodelling—are increasingly implicated in complex diseases including cancer and neurodegenerative disorders. Despite advances in standard therapeutic approaches, patient responses remain variable, largely due to genetic heterogeneity and epigenetic dysregulation. This highlights the need for incorporating epigenetic understanding into personalized medicine. …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 Read article
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AI Application in the Creation of Medications for COPD
Abstract: The crippling lung condition known as chronic obstructive pulmonary disease (COPD) is typified by a continuous restriction of airflow, which results in increased respiratory dysfunction and a reduced quality of life. The rising incidence of COPD worldwide emphasizes the pressing need for innovative pharmaceutical approaches to address the illness. Even though COPD care has advanced significantly, most current medications concentrate on symptom relief rather than disease change. This gap in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 01–05 Read article
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CTCHFA: Discovery of Circulating Tumor Cells in Metastatic Breast Cancer and Nonmetastatic Cancer by using Novel Hybrid Hierarchical Clustering Algorithm in Firefly Distance
Abstract: AbstractBlood testing for circulating tumor cells (CTCs) has emerged as one of the highest fields in cancer research. CTC detection are an early gene marker of reaction to systemic therapy, whereas their molecular characterization has a strong field that can be translated to individualized targeted treatments and spare breast cancer (BC) patients from unnecessary and ineffective therapies. Genomic research regarding CTCs monitoring for BC is limited due to the lack …
Published in Journal of Computer Technology & Applications · Vol. 6, Issue 1, 2015 · pp. 9–18 Read article