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1917 articles for “poly (ADP- ribose) polymerase -1” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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An Evaluation of the Efficacy and Safety Profile of Inula Racemosa in Patients of Restrictive Lung Diseases
Abstract: In this paper, we explain the procedure to evaluate the efficacy and safety profile of Inula racemosa in patients of restrictive lung diseases. The patients included in this study were selected from the outpatient clinic of a tertiary care hospital in North India. The present study was initiated on 45 patients suffering from restrictive lung diseases, 31 of these patients were followed up for 6 weeks. Remaining patients did not …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 4, Issue 3, 2015 · pp. 18–21 Read article
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Radiological and Clinical Aspects of Nasal Septal Deformities in Chronic Rhinosinusitis Patients in Northern Indian Population
Abstract: The present paper aims to study the radiological and clinical aspects of septum deformities in chronic rhinosinusitis patients in Northern Indian Population. The classification of nasal septum deformities is another challenge in the management of septum deformities patients suffering from chronic rhinosinusitis (CRS). The present study shows that the septum deformities are very common in CRS patients. The Mladina classification is also discussed in the paper. Results show that types …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 5, Issue 1, 2016 · pp. 60–64 Read article
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Magnitude of Perceived Stigma and Factors Associated with Care Givers of Schizophrenic Patients: The Case of Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia
Abstract: Stigma is a social process, experienced and characterized by exclusion, rejection, blaming or devaluation of a person or a group. Schizophrenia, especially because of its distinctive symptoms like common disruptive behavior and perceived dangerousness, exposes patients to stigma and discrimination. If families do not seek help because of stigma, young people will be at risk of longer durations of untreated illness. To assess magnitude and factors associated with perceived stigma …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 5, Issue 2, 2016 · pp. 1–9 Read article
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Benzimidic Acid Derivatives as Potential Anti-Escherichia coli Agent for Preventing Nosocomial Infections
Abstract: Based on the global fame of benzimidic acid/benzoic acid derivatives in exhibiting antimicrobial activities against a variety of pathogens (particularly nosocomial infections), two novel compounds (S1 and S2) of benzimidic acid scaffold were rationally designed from a hydrazine derivative and fabricated using the conventional synthesis technique. Through sophisticated instruments, the molecules were comprehensively characterized and investigated for antibacterial activity against pathogenic Escherichia coli strain (MTCC 2961). The novel benzimidic compound …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 9, Issue 1, 2020 · pp. 11–15 Read article
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A Study and Report on Assessment of Antibiotic Prescribing Patterns and Drug Resistance Among Various Infectious Diseases in Hospital
Abstract: Antimicrobial resistance remains the biggest cause of death worldwide. According to the World Health Organization, the age standardized mortality due to infectious diseases in India in 2008 was 377 per 100,000 persons, which is considered as highest in South Asia. This has led to the increased prescribing of antibiotics even at unnecessary conditions, which increased the rate of inappropriate prescribing of antibiotics, which in turn resulted in the emergence of …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 10, Issue 2, 2021 · pp. 5–35 Read article
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Predictive value of Systemic Inflammatory Response Syndrome score in assessing the clinical outcomes in patients with acute pancreatitis
Abstract: Background: The role of various clinical scoring systems to assess the severity and outcomes of acute pancreatitis is attracting a lot of attention to the experts. Purpose: We aimed to objectively reconfirm the predictive value of systemic inflammatory response syndrome (SIRS) score for predicting the various clinical outcomes of acute pancreatitis and also to evaluate the significance of monitoring SIRS score on day 1 and its duration. Methods: We retrospectively …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 11, Issue 1, 2022 · pp. 34–42 Read article
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Efficacy of Rapid Diagnostic Tests in Relation to ELISA in Hepatitis B and C Infection
Abstract: Background: Hepatitis B surface antigen and Hepatitis C antibodies in circulation are the common markers used for diagnosis of Hepatitis B and C infection. Though ELISA is the gold standard for detection of these markers, rapid diagnostic tests like immunochromatography is used in most of the centers for quick screening of cases. This study is undertaken to compare the result of both methods. Method: Both ICT and ELISA test were …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 10, Issue 2, 2020 · pp. 8–13 Read article
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Effects of Reading Task With or Without Verbalization on Heart Rate Variability
Abstract: In the present work, effect of different reading passages with or without verbalization on heart rate variability has been assessed. The study was conducted on 13 subjects with age group 18–25 years and no medical history. The lead-II electrocardiogram was recorded using MP35 amplifier (Biopac Inc, USA) while subject was in sitting position. The paradigm for recording was designed using Superlab 4.5. The paradigm includes reading four different passages: (i) …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 5, Issue 1, 2015 · pp. 1–4 Read article
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Assessment of Modern Contraceptive Utilization and Factors Associated Among Married Women of Reproductive Age Group at Mekelle City, North Ethiopia in August 2013
Abstract: Ethiopia is the second most populous nation in Africa. Its population has increased nearly seven times from 11.8 million at the beginning of the 20th century to about 80 million today. Where, only 27% in reproductive age groups are currently using modern contraceptive and number of factors could affect for effective use of modern contraception. But, still evidence showed that, as there is high maternal mortality and unwanted pregnancy. However, …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 5, Issue 2, 2015 · pp. 1–23 Read article
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Prevalence and Factors Associated with Aggressive Behavior among Patients with Schizophrenia at Ayder Comprehensive Specialized Hospital, Tigray, Ethiopia: a Cross-Sectional Study Design
Abstract: Introduction: Mental illness and aggression are often seen as inextricably linked. There is a growing body of evidence on aggressive behavior towards others by people with schizophrenia. Therefore, this study was designed to determine the prevalence of aggressive behavior and associated factors among people with schizophrenia. Method: Institutional based cross-sectional study was conducted during 6–31 May 2019 at the Ayder Comprehensive Specialized Hospital, Tigray, Ethiopia. A total of 423 participants …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 9, Issue 3, 2019 · pp. 1–10 Read article
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Prevalence of Perceived Stigma and Associated Factors among People with Epilepsy in Mekelle, Tigray, Ethiopia, 2019
Abstract: AbstractBackground: Epilepsy is defined as the most common, chronic, noninfectious neurologic disease that attacks around fifty up to sixty-nine million peoples without any age, sex, religion, ethnicity boundaries. Stigma is typically a practiced or predicted social system, characterized by exclusion or rejection of a person or group. Now a day perceived stigma among people with epilepsy become public health problems in the world. Perceived stigma in epileptic patients affects many …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 10, Issue 2, 2020 · pp. 24–35 Read article
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Descriptive Research Study to Assess the Knowledge of Mental Illness and its Prevention among People Residing in Selected Areas of Shrirampur
Abstract: Introduction: Mental disorder is a syndrome characterized by the clinical significant disturbance in the cognition, emotion regulation or behavior that reflects a dysfunction in the developmental processes underlying mental functioning psychological and biological Method And Material: A descriptive study was carried out to the ‘A study to assess the level knowledge of common people regarding mental illness and its prevention residing at selected areas Data was collected from selected forty …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 11, Issue 1, 2021 · pp. 33–36 Read article
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Uranium Content Anomalies in Groundwater of Moga District of Malwa Belt of Punjab (India) for the Assessment of Excess Cancer Risk
Abstract: Inductively coupled plasma mass spectroscopy (ICPMS) has been used to measure the Uranium (U) content of the ground water samples of Moga district of Malwa belt of Punjab, India. Out of the total number of habitations covered under this survey, 203 were having U content more than 30 ppb (WHO safe limit). Out of 203 habitations, we sorted out 56 with U concentration of more than 100 ppb in groundwater. …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 8, Issue 3, 2019 · pp. 18–24 Read article
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Comparison of Efficacy and Outcome of Radiocephalic and Brachiocephalic Arteriovenous Fistula in Patients of Chronic Kidney Disease
Abstract: Introduction: Hemodialysis is the most common treatment modality for patients with End-Stage Renal Disease (ESRD). Vascular access can be created in the form of arteriovenous fistula (AVF), arteriovenous graft (AVG) or central venous catheter (CVC). Material and Methods: The study was conducted in the Department of Urology, Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (PGIMS), Rohtak, Haryana, India from November 2016 onwards on patients who were admitted …
Published in Research and Reviews : Journal of Surgery · Vol. 8, Issue 1, 2019 · pp. 6–12 Read article
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A Comparative Study of Visual Outcome with Superior, Supero-temporal and Temporal Incisions in Manual Small Incision Cataract Surgery
Abstract: The purpose of the present study was to compare visual outcome in patients undergoing manual small incision cataract surgery with superior, supero-temporal and temporal incisions. The study was conducted between December 2014 and December 2015. For the prospective analysis, 102 cases meeting the inclusion and exclusion criteria were selected. The patients were randomly allocated to three groups of 34 each and surgeries were performed. In group A with superior, group …
Published in Research and Reviews : Journal of Surgery · Vol. 6, Issue 1, 2017 · pp. 1–5 Read article
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Pattern of Injuries in Cases of Alleged Rape Victim
Abstract: One of the most atrocious crimes in present society is rape. Rape has become now a major problem for administration all over the world (Verma 1979). This study was done in the department of Forensic Medicine and Toxicology, Assam Medical College and Hospital, Assam from 1st Nov 2010 to 31st Oct. 2011. Out of 171 numbers of Sexual Offences cases brought for medical examination in this department, a total 102 …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 1, 2018 · pp. 14–17 Read article
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Acute and Chronic Toxicity of Fluoride and Aluminum on Plant and Animal Models
Abstract: Ecotoxicological studies revealed aluminum (Al2SO4. 24 H2O) to be more toxic than fluoride (NaF) on a battery of test organisms (EC/LC50 of Al = 0.308 1.46 ppm; F = 116.6 232.8 ppm). During chronic exposure (Al = 3 ppm, F = 10 ppm for 60 90 days), there was reduction in growth parameters of organisms at different trophic levels in a food chain such as producers {dry weights (6.7 29.0) …
Published in Research and Reviews: A Journal of Toxicology · Vol. 1, Issue 1-3, 2011 · pp. 1–19 Read article
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Arsenic Induced Cytotoxicity Study Against Human Epithelial Carcinoma (HeLa) Cell
Abstract: The present investigation was undertaken to find out the cytotoxic effects of various amounts of arsenic exposure to human epithelial carcinoma (HeLa) cell. Cells were treated with a final concentration (0, 10, 20, 30, 40 and 50 µg/l) of arsenite in 5 ml MEM for 24 h where 0 concentration was considered as control. Cell viability was determined by the trypan blue (TB) exclusion test using hematocytometer and automated BIO-RAD …
Published in Research and Reviews: A Journal of Toxicology · Vol. 5, Issue 1, 2015 · pp. 1–8 Read article
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Histopathological Effects of Silver Nanoparticles on Gills and Liver of Freshwater Fingerlings Catla catla (Ham.)
Abstract: Fish is the best biomarker to identify the adverse effect on surroundings. Here, the fingerlings of major carp (Catla catla) were used as a model in the present work to investigate the toxicity caused by silver nanoparticles (AgNPs). The fish exposed to different concentrations of 10 μg/L and 30 μg/L AgNPs for 15 days were sampled at days 5, 10 and 15 for histology. This exposure caused organ injuries, and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 6, Issue 1, 2016 · pp. 18–27 Read article
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Safety of Ayurvedic Metal Origin Bhasma (Dhatu varga) through Acute Toxicity Studies: A Review
Abstract: Bhasma possess broad-spectrum therapeutic utility but are blamed due to frequently raising toxicity concerns. Although their safety has been evident with practice since ancient times, scientifically proven through toxicity studies, clinical safety, still comprehensive conclusive documentation is needed. Online published research articles on in vivo, oral single dose, acute toxicity studies on Bhasma of Dhatu Varga were searched through search engines and observations on behavioural, ponderal, autopsy, maximum tolerated dose …
Published in Research and Reviews: A Journal of Toxicology · Vol. 9, Issue 3, 2019 · pp. 43–50 Read article