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43 articles for “molecular interaction energy”
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In Silico Drug Designing of Breast Cancer in Homo sapiens
Abstract: Breast cancer is a severe health concern in India, with the highest mortality rate among women. It is brought on by uncontrolled cell division and has the potential to spread to other body regions. As a transcription factor, interactions with estrogen receptor (ER) alpha are primarily responsible for malignant tumors through regulating the transcription of numerous genes. Because most of the medications now used to treat breast cancer have significant …
Published in Research and Reviews : Journal of Computational Biology · Vol. 11, Issue 2, 2022 · pp. 12–27 Read article
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Molecular Docking Studies of Wildtype P53 with Damnacanthal and Scopoletin- Phytochemicals Derived from Morinda Citrifolia
Abstract: Cancer is a prominent cause of mortality globally, and it has the potential to impact any region of the body. The tumor suppressor protein P53 plays a significant role in inhibiting tumor growth by regulating DNA repair, inducing cell cycle arrest, promoting senescence, and triggering apoptosis when confronted with genotoxic stress. P53 is found mutated in 50% of cancers where it loses its tumor suppressive properties and gains oncogenic properties …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 2, 2023 · pp. 20–31 Read article
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Catalytic Activity Advancements in Organometallic Chemistry
Abstract: Organometallic chemistry is essential to catalysis and synthesis, helping to shape a wide range of chemical reactions. The study of the interactions between organic compounds and metal elements is known as organometallic chemistry. Modern synthetic chemistry and catalysis have been greatly influenced by the field of organometallic chemistry. It entails the investigation of substances that have metal-carbon bonds because they can have special catalytic and reactive qualities. Applications for these …
Published in Journal of Catalyst & Catalysis · Vol. 10, Issue 2, 2023 · pp. 10–25 Read article