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219 articles for “Park”
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In vivo Modulatory Effect of Clerodendrum Splendens (Glory Blossom) in Aluminum Induced Alzheimer Diseases and Lonchocarpus Sericeus in Rotenone Induced Parkinson’s Disease on Na+/K+ Atpase (Sodium Pump) in the Cerebral Tissues of Male Albino Wister Rats
Abstract: Elegant research has shown that plants are useful for both curative and preventive purpose on the humans populous. Prevalent among diseases associated with humans are neurological diseases which affect a large sector of the population especially the elderly. The most common neurological diseases are Parkinson and Alzheimer disease which affect a large sector of the brain and also cause an imbalance in brain electrolyte. Among such electrolytic mechanisms of the …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 2, 2023 · pp. 31–36 Read article
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Cloud Driven Smart Car Parking System
Abstract: Effective infrastructure management has been forced to evolve as a result of urbanisation, particularly in the transportation sector. Among the various challenges faced by urban mobility, effective parking management is a crucial concern. The "Cloud Driven Smart Car Parking System" a state-of-the-art innovation that combines cloud-integrated technologies to revolutionise urban parking, is introduced in this research. The essay discusses the serious drawbacks of traditional parking management systems and highlights the …
Published in Journal of Instrumentation Technology & Innovations · Vol. 14, Issue 1, 2024 · pp. 30–37 Read article
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Exploring the Complexities of Parkinson’s Disease
Abstract: Parkinson’s disease (PD) is a neurological disorder, primarily affecting older adults, marked by both motor and non-motor symptoms. This review explores PD as a multisystem disorder that influences the central, enteric, and autonomic nervous systems, along with the immune system and gastrointestinal tract. Key pathogenic features include the degeneration of dopamine-producing neurons in the substantia nigra and the formation of Lewy bodies containing misfolded α-synuclein proteins. The bradykinesia, tremors, stiffness, …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 3, 2024 · pp. 1–8 Read article
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Machine Learning-Based Disease Prediction: A Comparative Analysis for Diabetes, Brain Tumor, and Parkinson's Disease
Abstract: This paper presents a web-based disease prediction system that integrates machine learning and deep learning techniques to assist in the early detection of Parkinson’s Disease, Diabetes, and Brain Tumors. By utilizing clinical data and MRI images, the platform provides rapid and interpretable predictions to support proactive health management. Logistic Regression models are applied to classify structured datasets for predicting Parkinson’s disease and Diabetes, making use of their effectiveness in binary …
Published in Current Trends in Signal Processing · Vol. 15, Issue 2, 2025 · pp. 44–54 Read article
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Engineering Anti-Tau Monoclonal Antibodies for Alzheimer’s Disease and Parkinsonian Tauopathies: A Biotechnological Perspective
Abstract: Neurodegenerative disorders such as Alzheimer’s disease and Parkinson’s disease are characterized by progressive neuronal loss associated with abnormal protein aggregation. Among these, tauopathies are defined by the accumulation of hyperphosphorylated tau protein, which plays a central role in disease progression. Advances in biotechnology have enabled the development of anti-tau monoclonal antibodies (mAbs) as promising therapeutic agents aimed at neutralizing pathological tau species and inhibiting their propagation. This review provides a …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 · pp. 52–58 Read article
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PLC Based Smart Car Parking System
Abstract: In modern industrialization and urbanization, there are rapid developments in automotive sector. Metropolitan and even small cities in India are heavily dense. People are experiencing huge traffic problem and insecurity regarding their vehicle. The land is becoming less but the population of human is growing day-by-day. This scenario is obvious in modern developed cities. Therefore is very limited and space need to be saved in every aspect of life. By …
Published in Trends in Electrical Engineering · Vol. 8, Issue 3, 2018 · pp. 66–71 Read article
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An Open Clinical Study to Evaluate the Efficacy of Shirobasti and Nasya with and without Levodopa in the Management of Kampavata w.s.r. to Parkinson’s Disease (PD)
Abstract: Background: Kampavata (Parkinson’s disease), considered as Vata Nanatamaja disorder, is the most common progressive neurodegenerative disorder characterized by bradykinesia, resting tremors, muscular rigidity, shuffling gait and flexed posture accompanied by a variety of non-motor symptoms, including autonomic, sensory, sleep, cognitive and psychiatric disturbances. Aim and Objectives: To study the effect of Shirobasti and Nasya in the management of Kampavata (PD) with levodopa and without levodopa. Materials and Methods: The present …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 8, Issue 3, 2021 · pp. 15–28 Read article
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A Rare Cause of Parkinsonism—Manganese Toxicity
Abstract: A 43-year-old male presented with six months history of gradual onset and progressive bradykinesia, tremors of upper limbs and walking difficulty in the form of imbalance and short shuffling gait. He also had slurring of speech with hypophonia. Neurological examination revealed slow broken saccades, rigidity with cogwheeling, bradykinesia and short shuffling, festinant gait. He had action and postural tremors of upper limbs. Pull test was positive. Thus, a diagnosis of …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 9, Issue 1, 2019 · pp. 29–32 Read article
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Parkinson’s Diagnosis and Differential Diagnosis: A Review
Abstract: Parkinson’s disease is a progressive degenerative disorder of the cerebellum occurs in all ethnic groups has an equal sex distribution. It is characterized by slowly progressive akinesia, rigidity, postural abnormality, and resting tremor. Because of its crippling nature and non-availability of curative treatment, Parkinson’s disease has remained a great problem. Though in modern medical science a lot of research works have been done. Some medication like Carbidopa, Levodopa, recently some …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 11, Issue 1, 2021 · pp. 37–44 Read article
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Dental Pulp Stem Cells Derived from Wisdom Teeth as Multitarget Biological Modulators of Alzheimer’s and Parkinson’s Disease: Mechanistic Insight and Translational Perspective
Abstract: Alzheimer’s disease and Parkinson’s disease are chronic, progressive neurodegenerative disorders with complex pathogenic pathways such as neuroinflammation, oxidative stress, mitochondrial dysfunction, synaptic degeneration, and reduced neurotrophic signalling. Despite the large amount of research, the pharmacological treatments in use offer only symptomatic relief and cannot significantly prevent or slow down disease progression sufficiently; new pathogenetic treatment strategies are necessary. In recent years, stem cell-based approaches have gained interest as potential therapeutic …
Published in Research and Reviews: A Journal of Dentistry · Vol. 17, Issue 2, 2026 · pp. 7–28 Read article
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Unraveling the Nexus: Parkinson's Disease, Alpha-synuclein, Desulfovibrio, and the Gut Microbiome
Abstract: Parkinson's disease (PD) is now recognized as a chronic condition which is once considered a highly intricate disorder involving the central, autonomic, and enteric nervous systems. The prevailing perspective attributes the disease by the formation of Lewy bodies, primarily triggered by the misfolding of α-Synuclein, leading to the demise of dopaminergic neurons in the substantia nigra. Constipation, one of the most common non-motor symptoms in PD patients, is believed to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 1, 2024 · pp. 18–28 Read article
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Non-Enzymatic Glycation in Alzheimer’s and Parkinson’s Disease: A Molecular Approach to Pathology and Recent Advances
Abstract: Non-enzymatic glycation, a biochemical process by which reducing sugars spontaneously bind to proteins, leads to the formation of advanced glycation end-products (AGEs), which have emerged as critical contributors to the pathogenesis of several neurodegenerative diseases, particularly Alzheimer’s disease (AD) and Parkinson’s disease (PD). The accumulation of AGEs can significantly alter protein structure, stability, and function, triggering a cascade of detrimental effects, including increased oxidative stress, heightened neuroinflammation, and the promotion …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 36–41 Read article
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Parkinson’s Disease Detection on Spiral Images Using CNN with Meta-Classifiers
Abstract: In this work, we provide a detailed method for identifying Parkinson’s Disease (PD) by integrating Convolutional Neural Network (CNN) and meta-classifiers. Through the utilization of a varied dataset consisting of handwritten spiral images, our methodology demonstrates commendable accuracy across a range of models. Specifically, our CNN model with meta-classifiers surpasses alternative approaches, achieving an impressive accuracy rate of 95.07%. By utilizing pre-established VGG16 and ResNet50 architectures as bases, the region-based …
Published in Journal of Computer Technology & Applications · Vol. 16, Issue 1, 2025 · pp. 55–66 Read article
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IoT based Automated Car Parking System
Abstract: AbstractThis work is focussed on solving one of the major issues that modern metropolitan cities facing now i.e. “How to maximise the utility of space for car parking”? Since the world is getting automatic day by day, this project is a small leap towards automated space management system. In this project we incorporated micro controller along with couple of type of sensors to detect incoming and outgoing of cars along …
Published in Journal of Microcontroller Engineering and Applications · Vol. 7, Issue 2, 2020 · pp. 25–29 Read article
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Investigating Curcumin Phytocompounds as Prospective Parkinson's Disease Therapeutic Agents: A Computational Method that Targets LRRK2 Protein
Abstract: Objective: Parkinson’s Disease is the second stage predominant neurodegenerative illness. Primary aetiology is still unknown. One of the biggest battlegrounds in modern medicine is discovering the cause of Parkinson’s disease (PD), as well as the hunt for palliative treatments and, if feasible, a cure. The objective of this work is to identify the phytocompounds from curcumin (curcuma longa) for the treatment of PD. Curcumin, a well-researched phytochemical, has been suggested …
Published in Research and Reviews : Journal of Computational Biology · Vol. 12, Issue 3, 2023 · pp. 55–67 Read article
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An overview on the diagnosis and approaches in pharmacological management of Parkinson’s disease
Abstract: Parkinson’s disease (PD) might be a mutual neurodegenerative disease considered by a movement disorder containing rest tremor, bradykinesia, rigidity, and postural instability, and second-leading reason of dementia and is categorized by an advanced loss of dopaminergic neurons within the neural structure alongside the occurrence of intraneuronal α-synuclein-positive enclosures. PD is identified where bradykinesia happens along with rigidity or tremor within the existence of supporting features. The diagnosis is clinical, and …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 11, Issue 1, 2021 · pp. 1–8 Read article
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Effect of Neuromuscular Electrical Stimulation (NMES) on the Measures of Hyolaryngeal Elevation during Swallow in Individuals with Parkinson’s Disease
Abstract: Inadequate hyolaryngeal elevation is one among the leading cause of aspiration and dysphagia in individuals with Parkinson’s disease. Treatment protocols specific in strengthening the hyolaryngeal elevation are seldom studied in this population. Neuromuscular Electrical Stimulation (NMES) for swallow is a recent technical advancement in the arena of dysphagia rehabilitation that targets on stimulating the laryngeal extrinsic and the suprahyoid muscles, responsible for adequate movements of the hyolaryngeal complex. The literature …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 12, Issue 2, 2022 · pp. 18–25 Read article
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MULTI STOREY CAR PARKING SYSTEM
Abstract: A City like Delhi has over five million car and two wheelers on its road , but not enough parking space . The demand for parking space on a n average in the main market of Delhi , outstripped demand by 43%. Multi-storey car parking provide lower building cost per parking slot, as they typically required less building volume and less ground area then a conventional facility with the same …
Published in Journal of Construction Engineering, Technology & Management · Vol. 9, Issue 1, 2019 · pp. 26–29 Read article
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Current Prospective of NLCs in Parkinson’s Disease: An Outlook
Abstract: Parkinson's disease (PD) is 2nd most a neuro-degenerative disorder of the central nervous system affecting 7–10 million people of worldwide as the report of WHO 2014. It occurs due to the death of dopamine-generating cells in the substantia nigra, a region of the midbrain. It is characterized by tremor, rigidity, bradykinesia, dementia, depression and falls or emerges with the progression of the disease. Ropinirole Hydrochloride is a drug of choice …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 2, 2018 · pp. 18–29 Read article
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Formulation Development, Characterization and in-vitro Evaluation of Nano-Lipid Carriers of Ropinirole HCl for Persistent Parkinsonian Management
Abstract: According to a report of World Health Organization (WHO) 2014, Parkinson's Disease (PD) is the second-most neurodegenerative dysfunction of the central nervous system (CNS) of human being effecting 7–10 million people worldwide. It is primarily due to the death of dopamine-generating cells in the substantia-nigra of midbrain. It is symptomatized by tremor, rigidity, bradykinesia, dementia, depression and falls or emerges with the progression of the disease. Ropinirole HCl is a …
Published in Trends in Drug Delivery · Vol. 6, Issue 1, 2019 · pp. 14–23 Read article