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1830 articles for “significance” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Comparative Effectiveness of Surgical and Nonsurgical Management for Patients with Single Level Lumbar Disc Herniation in terms of Symptom Severity and Quality of Life
Abstract: Background: Sciatica is one of the most severe forms of low back pain, with a lifetime prevalence of approximately 30 percent. Aim: To assess the short-term and long-term efficacy of surgical and conservative care in the incidence of sciatic symptoms and quality of life in standard clinical settings among patients with lumbar disc herniation. Material and Method: It was a retrospective study conducted at the Medical Trust Hospital, Kochi, India. …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 10, Issue 1, 2020 · pp. 25–29 Read article
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The Fluctuation of Blood Glucose Level in Stroke Patients without History of Diabetes Mellitus: Relationship with its Outcome
Abstract: Purpose: In the present study we aimed at evaluating the fluctuation of fasting glucose levels and analyzing its relationship with outcomes in nondiabetic patients with ischemic stroke and intracerebral hemorrhage. Methods: We conducted a prospective study involving 316 nondiabetic patients (225 male, 91 female) with hemorrhagic and ischemic stroke, who were admitted to the Pyongyang University of Medical Sciences Hospital, Democratic People’s Republic of Korea from April 2017 to December …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 10, Issue 3, 2020 · pp. 5–11 Read article
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The Effects of Dual Task Exercise Versus Task Specific Locomotion Training to Improve Walking Ability in Stroke: A Comparative Study
Abstract: Purpose of the study: The main aim of the study is to see whether the Dual-Task exercise versus Task Specific locomotion training improve gait/locomotion in chronic stroke patients. Participants: The study included a total of 30 participants, comprising both males and females, who had chronic stroke. All participants were at least limited community ambulatory individuals with Berg Balance Scale scores ranging from 41 to 56. Interventions: All the subjects were …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 13, Issue 1, 2023 · pp. 13–28 Read article
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Glutathione: Postoperative Study in Breast Carcinoma
Abstract: Breast cancer represents a significant problem in the world. Glutathione a tripeptide is found in all mammalian tissues. Thus any change in its synthesis or utilization can profoundly influence the redox status of cells. In this study blood sample was collected from 60 FNAC confirmed breast cancer patients (preoperative and postoperative three months) and 30 normal healthy controls for the estimation of glutathione. There was significant increase in glutathione in …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 7, Issue 1, 2018 · pp. 3–6 Read article
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Up-Regulation of TNF-α by Ethanol Extract of Moringa Oleifera in Benzene-Induced Leukemic Wister Rat: A Possible Mechanism of Anticancer Property
Abstract: Ethanol extract of Monringa oleifera (EMO) has been shown to possess anti-cancer properties in animal models. The mechanisms of action of its anticancer properties have not been fully demonstrated. We induced leukemia in two groups of seven rats each by intravenous injection of benzene chromasolv solution (0.2 mL) 48 hourly for 4 weeks. EMO (0.2 ml of 100 mg/mL) was administered orally by gavage, after leukemia induction, daily for 4 …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 3, Issue 3, 2014 · pp. 16–21 Read article
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Pattern of Care and Pattern of Survival Study in ca Cervix: Implications of a Published Study
Abstract: This article is being written in the context of the recently published multi-institutional study of POSCC for patients of cervical cancer in India. This study involves both private and public funded institutions and has hospitals from most parts of the country. This study is of utmost relevance in current day India, since India alone accounts for one-fourth of the total burden of disease. Stage I cervical cancer has a fairly …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 4, Issue 3, 2015 · pp. 14–18 Read article
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Knowledge and Skill of Staff Nurses Regarding Breast Cancer and Breast Self-Examination
Abstract: Breast cancer comprises about 25% of all female cancers. Its incidence is rising constantly, also among younger women. Every 15 min, three breast cancer cases are diagnosed and one woman dies of this disease. Breast cancer is the leading cause of death among women in the age group of 40–44 years and the incidence increases significantly after 50. This experimental pre-test post-test control group design aims to evaluate the effectiveness …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 5, Issue 2, 2016 · pp. 1–5 Read article
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Correlation of Ki-67 Score with Nottingham Histological Grading in Carcinoma Breast: A Single Institution Experience
Abstract: Though it is reasonably well established that Ki-67 positivity is an independent predictor of ultimate prognosis and course of carcinoma breast and its recurrence, many lacunae exist. Ki -67 score correlation with histological grading will establish importance of nuclear antigen Ki-67 as prognostic factor in Indian population. This study was aimed to assess histological grading of breast carcinoma by Nottingham Grading System (Modified Scarff- Bloom- Richardson system) and to correlate …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 6, Issue 1, 2017 · pp. 1–5 Read article
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To Develop Self-instructional Module on ‘Umbilical Cord Stem Cell Collection, Preservation and Utilization’ and Evaluate its Effectiveness on Improving the Knowledge of Operational Level Nurses
Abstract: Umbilical cord stem cell based regenerative and cellular medicine has now become a fascination for all. The umbilical cord blood, donated by mothers after the birth of newborn, has become an accepted source of hematopoietic stem cells for bone marrow reconstitution. They play an important role in the treatment of blood and immune system related genetic diseases, cancers, and blood disorders. This study is aimed to assess the knowledge of …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 3, 2020 · pp. 10–22 Read article
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Assess the Effectiveness of Progressive Muscle Relaxation Therapy on Health Status among Blood Cancer Patients Receiving Cancer Treating Medications in Selected Hospital
Abstract: Introduction: Cancer can be regarded as a group of diseases characterized by an i) abnormal growth of cells ii) ability to invade adjacent tissues and even distant organs, and iii) the eventual death of the affected patient if the tumour has progressed beyond that stage when it can be successfully removed. Cancer can occur at any site or tissue of the body and may involve any type of cells. Cancer …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 10, Issue 2, 2021 · pp. 1–20 Read article
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Comparative Evaluation of Genotoxicity in Peripheral Blood Mononuclear Cells in Oral Precancer and Cancer Patients Using Single Cell Gel Electrophoresis
Abstract: In the present study the comet assay was performed in peripheral mononuclear cells to evaluate DNA damage among tobacco chewers and smokers. The assay provides a quick, accurate and sensitive way to detect various forms of DNA damage in individual cells. The study comprises 50 oral cancer patients, 12 oral submucous fibrosis patients and 10 healthy controls. The length of the comet tail was used to determine the level of …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 11, Issue 2, 2022 · pp. 26–34 Read article
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Relation of Thyroid Profile in Gall Stone Disease Patients
Abstract: Introduction: Gallstone disease is a very common gastro-intestinal disorder which is present worldwide. They may form because of many different disorders and the basis for it is impaired metabolism of cholesterol, bilirubin and bile acid and is characterized by formation of stones in hepatic or common bile duct or gall bladder. There has been a discussion, regard to the relation of thyroid disorders and gallstone disease, there are several explanations …
Published in Research and Reviews : Journal of Surgery · Vol. 6, Issue 2, 2017 · pp. 8–12 Read article
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A quasi experimental study on effect of sponge bath on reducing discomfort among post operative general surgery patients in a selected Hospital at Chandigarh 2011
Abstract: Background: Bathing is considered a necessary and therapeutic nursing intervention since it provides hygienic care for clients. Bathing removes sweat, oil, dirt and micro-organisms from the skin, assists in decreasing body odour and the potential for infection, stimulates circulation and provides clients with a refreshed and comforted feeling. Objective: To study the effect of sponge bath on reducing discomfort among post operative general surgery patients. Methods: Study was conducted on …
Published in Research and Reviews : Journal of Surgery · Vol. 6, Issue 2, 2017 · pp. 1–5 Read article
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Treatment Modalities of Planter Fasciitis: A Two Years’ Experience
Abstract: Back-ground: Plantar fasciitis causes soreness or tenderness of the sole of the foot under the heel, which sometimes extends into the medial arch. Objective: A study was conducted to ascertain which treatment modality provides the best results for heel pain patients. Method: The therapies included orthoses, stretching, ultrasonic therapy and local infiltration with a combination of a local anaesthetic and corticosteroid injection. These were included based on the availability of …
Published in Research and Reviews : Journal of Surgery · Vol. 7, Issue 3, 2018 · pp. 21–25 Read article
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Patterns and Risk Factors of Gestational Diabetes Mellitus among Mothers Who Visited Antenatal Clinics in Public Health Centers of Mekelle City, Tigray, Ethiopia, 2015
Abstract: Gestational diabetes mellitus is associated with significant morbidity in the short and long-term, for both mother and offspring. It is now well established that women with a history of GDM are at a significant increased risk of developing type-2 diabetes, later in life. There were limited studies conducted on pattern and risk factors of gestational diabetes mellitus in Tigray region. The aim of this study is to assess patterns and …
Published in Research and Reviews : Journal of Surgery · Vol. 5, Issue 2, 2016 · pp. 12–20 Read article
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Early Postoperative Outcome of Primary Closure versus T-Tube Drainage of Common Bile Duct after Open Choledocholithotomy
Abstract: Background: Choledocholithiasis is the formation of stones in the common bile duct (CBD). These stones are removed by performing CBD exploration and the closure can be done over T-tube or primarily without T-tube. The method of T-tube drainage comes with many complications and hence, nowadays, there is tendency to close CBD primarily to avoid the tube-related complications. Aims: To compare the early postoperative outcome of primary closure versus T-tube drainage …
Published in Research and Reviews : Journal of Surgery · Vol. 8, Issue 1, 2019 · pp. 13–18 Read article
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Negative Pressure Wound Therapy and Intermittent Irrigation with Systemic Antibiotic Suppression followed by One-stage Revision in Delayed Periprosthetic Hip Infection Cases: Reinfection Rate
Abstract: Background: Success rate of one-stage revision remains controversial in patients with delayed periprosthetic joint infection after primary cementless hip arthroplasty. We evaluated the reinfection-free efficacy of negative-pressure wound therapy (NPWT) and intermittent pulsatile irrigation (IPR) using chlorhexidine/povidone iodide combined with systemic antibiotic suppression (SAS) followed by one-stage exchange procedure with NPWT in those patients. Materials and Method: Reinfection rate was assessed in randomly selected forty-two cases (group A) with NPWT-IPR-SAS …
Published in Research and Reviews : Journal of Surgery · Vol. 11, Issue 2, 2022 · pp. 7–15 Read article
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Effect of Ethylene Glycol Monomethyl Ether on Testicular Antioxidant System in Adult Rats
Abstract: Ethylene glycol monomethyl ether (EGME), an environmental contaminant, which is widely used as a solvent especially in lacquers, paints, dyes, pesticides, liquid soap, cleaning solution & cosmetic, chemical intermediates, as a diluent for hydraulic brake fluid etc on industrial scale, has been shown to induce reproductive abnormalities in male rats. The precise nature and mechanism of action of EGME on the male reproductive system is not clear. In the present …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 2, 2013 · pp. 1–6 Read article
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In Vivo and In Vitro Antioxidative Efficacy of Naringenin on Cadmium -Induced Toxicity in Rats
Abstract: The aim of the study was to investigate the in vivo circulating antioxidants level such as vitamin C, vitamin E and GSH in Cadmium (Cd) induced toxic rats and the protective efficacy of naringenin via in vitro free radical scavenging assays. In this investigation cadmium chloride (5 mg/kg body weight (b.w) was administered orally (p.o) for 28 days to induce toxicity. Naringenin was pre-administered orally (50 mg/kg body weight) for …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 3, 2013 · pp. 9–16 Read article
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Pyrethroid Mediated Some Macromolecular and Biochemical Changes in Freshwater Teleost
Abstract: Abstract In present investigation, a freshwater fish Channa punctatus was exposed for 21 days to synthetic pyrethroid malathion at sublethal concentrations of 0.007mg L−1 and 0.093 mg L−1 that represented 10% of the 96 h LC50 of the pesticide for this fish. Tissue samples were collected at the end of the experiment and analyzed to determine oxidant/antioxidants status (catalase, LDH, DNA content, protein content, cortisol, etc.) of the fish. Enzyme …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 2, 2020 · pp. 14–21 Read article