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626 articles for “Human epidermal growth factor receptors (HER-2)” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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In Silico Drug Design for Mycobacterium tuberculosis and Development of Host–Pathogen Interaction Network and Molecular Docking Procedures
Abstract: Objective: A leading cause of illness is the contagious disease tuberculosis (TB), this infection with Mycobacterium tuberculosis complex (MTBC) particularly M. tuberculosis and M. africanum, is what causes tuberculosis. Diverse receptor proteins (mycobacterial proteins) with various 3D structures and functions were evaluated to access the multi-domain antimycobacterial action of ligands. The specific receptor proteins PDB ID: 3PTY, PDB ID: 4OW8, PDB ID: 5KWA, and PDB ID: 3ZXR, were opted for …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 1–19 Read article
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ECZEMA {Atopic Dermatitis}
Abstract: Many of the persons around the world suffer from eczema which is also called atopic dermatitis. It is a kind of skin disorder that makes the skin dry, itchy, and sometimes even painful. There is no specific age group who got affected by this particular disease, no matter what age you are. But particularly it is seen that the children were mostly affected by eczema, as there is no cure …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 · pp. 53–66 Read article
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Knowledge and Perception of the Ill Effects of Cosmetics Among Late Adolescent Girls
Abstract: The current research focused on examining the knowledge and attitude towards the negative effects of cosmetics among late adolescent girls studying at DM WIMS Pharmacy College in Meppadi, Wayanad. The study aimed to evaluate the level of knowledge and attitude toward the harmful effects of cosmetics among these girls and explore any potential associations between their knowledge, attitude and selected socio-demographic variables. To conduct the study, a quantitative approach using …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 15–20 Read article
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Uncovering the Comparative Efficacy of Antiviral Drugs and Caricapapaya Phytocompound as VP2H inhibitors in Ebola virus: An Insilico Molecular Docking Analysis
Abstract: The Ebola virus is a fatal disease that transmits from wild animals to humans. Infected individuals' body fluids such as spit, blood, perspiration, faeces, blood, saliva, breast milk, sperm, or fomites can transmit Ebola. Adhesion to cell membranes and penetration into the host organism are essential aspects in viral growth. The presence of VP24, as well as nucleoproteins and structural proteins, is necessary for nucleocapsid formation and integration. The inhibition …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 62–78 Read article
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Identification of Secondary Metabolites from Zingiber officinale as Inhibitors for Keap 1-Nrf2 small Molecules through Molecular Docking Techniques
Abstract: Objective: Therapeutic plants aid in treating cancer-based cell signaling pathways and preventing certain risk factors. Zingiber officinale has a variety of anti-inflammatory characteristics also contributing to enhanced immunity, reducing cancer risk and used to target the KEAP NRF2. When overexpressed in response to oxidative stress and DNA damage, elevates the risk of developing multiple cancers. NRF2 cellular sensors, which also control and coordinate their expression aid in defending healthy cells …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 35–48 Read article
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Thoracolumbar Spine Surgery: Peri-operative Nursing Care Needs and Quality of Life
Abstract: Aim and Objective: To explore the nursing care needs of the patients after thoracolumbar spine surgery during preoperative, post-operative, home care and to assess the quality of life. Design: An exploratory study. Methods: The study was conducted among 50 patients who had undergone thoracolumbar spine surgery in neurosurgery units of tertiary care hospital from July 2018 to September 2020. The nursing needs were assessed by interviewing participants telephonically using an …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 13–23 Read article
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Quality of Sleep Among Patients with Chronic Renal Failure
Abstract: Renal failure is the partial or complete impairment of kidney function. Inability to eliminate metabolic waste products and water, along with functional disruptions in all bodily systems, result in the condition known as renal failure. Renal failure can be categorized as either acute or chronic. Chronic renal failure refers to the gradual and irreversible deterioration of the nephrons in both kidneys. It is characterized by either kidney damage or a …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 22–28 Read article
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Strategies for Flood Mitigation
Abstract: The world has always experienced change. Water-too much or too little is the most common cause of migration and a city's downfall. The notable and significant distinction right now is that we are seeing it in real-time for the first time in human history. We contributed to the dangers that were produced, and we contributed to the remedies that will influence the pace and scope of change and disruption. We …
Published in International Journal of Rural and Regional Development · Vol. 1, Issue 1, 2023 · pp. 1–9 Read article
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A Study to Evaluate the Effectiveness of Planned Teaching Program of Environmental Health Among Community People in Selected Rural Area of Gwalior
Abstract: Context: Environmental health is the subfield of public health that focuses on identifying and altering environmental contributors to illness and injury. The state of the environment in a certain area, especially as it relates to ecological diversity and pollution. The purpose of this research was to evaluate the efficacy of an environmental health education program for the local population. This study follows a quantitative research approach for its methodology. The …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 23–32 Read article
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A Molecular Docking Study: Targetting HIV-1 Integrase Protein Against Selected Phytocompounds from Calophyllum Lanigerum
Abstract: Objectives: The most common form of HIV that causes AIDS is HIV-1. The World Health Organization has estimated roughly 75 million plus HIV-1 infections till date and roughly 40 million deaths (as of 2021). Thus, this study was done to identify natural compounds from Calophyllum lanigerum, a medicinal plant largely endemic to South-East Asia, to inhibit the spread of this disease. It did so by using molecular docking methods, Lipinski …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 2, 2023 · pp. 43–55 Read article
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From Ancient DNA to Modern Livestock: Paleogenomics
Abstract: Paleogenomics, an interdisciplinary blend of paleontology and genomics, has revolutionized our understanding of ancient DNA and its applications across various fields. In Animal Genetics and Breeding, this field has emerged as a pivotal tool providing invaluable insights into the historical genetics of domesticated animals. By reconstructing and analyzing the genomes of long-extinct organisms, paleogenomics sheds light on genetic diversity, evolutionary dynamics, and adaptations of ancient species. Paleogenomics significantly impacts animal …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 1–6 Read article
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Impact of Education on Knowledge and Perception of Antenatal Care Among Primigravida Mothers, Residing in Farasan, Kingdom of Saudi Arabia: A Community-based Interventional Study
Abstract: Pregnancy is one of the most cherished phases in the life of a woman. This timeframe holds immense importance for both the mother and the infant. Offering appropriate prenatal care during pregnancy is crucial for the health of the mother and the growth of the foetus. It provides a chance to promote sound parenting techniques and healthful conduct. The quality of prenatal care contributes to sustaining overall well-being throughout an …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 6–13 Read article
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Coronary Vascular Disease: A General Review with Specific Reference to Etiology
Abstract: Cardiovascular disease (CVD), the foremost cause of mortality worldwide, has surged by 60% globally, reaching 20.5 million deaths in 2021 from 12.1 million in 1990, as per the latest report from the World Health Federation. While this increase is alarming on a global scale, it raises even greater concerns in countries like India where heart ailments are afflicting individuals at a younger age. The escalation of CVD among the younger …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 1, 2024 · pp. 36–42 Read article
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Development and Formulation of Chocolate-coated Seeds Bar
Abstract: Vitamins E, D, and B6 minerals like zinc and selenium and amino acids like glutamine all play a role in the body's immune system development. Edible seeds are a great source of protein, healthy fats, fiber, and important minerals like magnesium, potassium, calcium, iron, and zinc in addition to vitamins B1, B2, B3, and E. Examples of edible seeds include pumpkin, flax, sesame, sunflower, mustard, amaranth, oat, barley, black rice, …
Published in International Journal of Nutritions · Vol. 1, Issue 1, 2024 · pp. 1–12 Read article
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The Study of Nutritional Requirements and Physiological Changes in Space Station
Abstract: This article focuses on the impact of physiological adaptations to weightlessness on nutrient and food requirements in space. These modifications entail reductions in body water and plasma volume, which affect the cardiovascular and renal systems. Spaceflight poses intricate and predominantly detrimental effects on the human body, spanning both short and long durations. Long-term weightlessness leads to significant issues like muscle atrophy, skeletal deterioration, cardiovascular function deceleration, reduced red blood cell …
Published in International Journal of Nutritions · Vol. 1, Issue 2, 2024 · pp. 7–10 Read article
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Removal of Chloride from Ground Water Using Natural Adsorbent: Water Hyacinth
Abstract: Groundwater contaminants in rural areas often include chlorides and hardness. Nowadays, due to water scarcity, there is a need to utilize groundwater for construction purposes. According to IS 456:2000, the chloride content in water used for mixing and curing concrete must not exceed 2000 mg/l for plain concrete and 500 mg/l for reinforced concrete work. An excess amount of chloride in water causes the deterioration of structures. Concrete durability and …
Published in International Journal of Pollution: Prevention & Control · Vol. 2, Issue 1, 2024 · pp. 49–55 Read article
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Seasonal Variations of Air Quality Measures In Warri and Effurun, Delta State, Nigeria.
Abstract: Air quality in Urban Cities like Warri and Effurun has been deteriorating over time. The distribution levels of air pollutants in the Warri and Effurun environments may be related to both natural and man-made factors. In addition to evaluating the quality of rainwater with regard to pH, heavy metals (Fe, Pb, Cd, As, Hg, CU, Zn), and some anions (Cl-, NO3-, SO42-, CO32-), this project study aims to investigate, using …
Published in International Journal of Pollution: Prevention & Control · Vol. 2, Issue 1, 2024 · pp. 23–48 Read article
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Revisiting the Role of Mindfulness-based Stress Reduction in the Management of Rheumatoid Arthritis
Abstract: Rheumatoid arthritis (RA) is a type of arthritis characterized by a chronic inflammatory disorder that primarily affects the lining of the synovial joints resulting in progressive disability in the movement of diarthrodial joints and arthralgia. It is a debilitating disease associated with premature death and socioeconomic burdens. Its pathogenesis is multifactorial with an individual course of progression where psychological stress is considered to be one of the risk factors associated …
Published in International Journal of Vaccines · Vol. 1, Issue 1, 2024 · pp. 19–28 Read article
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The Impact of Dietary Components on Lactation: A Critical Review
Abstract: Infant growth and well-being depend on an adequate and species-specific amount of nutrients, antibodies, and immunological components, which are provided by human breastfeeding, the cornerstone of newborn sustenance and development However, some moms struggle with producing inadequate milk, which can put the health advantages of nursing for both mother and child in jeopardy and cause stress, anxiety, and perhaps early weaning. This review discusses the fascinating idea that food changes …
Published in International Journal of Nutritions · Vol. 1, Issue 1, 2024 · pp. 31–36 Read article
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Addiction to Social Media Platforms Among Undergraduate Students
Abstract: Social media addiction is characterized by an excessive preoccupation with social media platforms, leading to an inability to control the urge to engage with them, which in turn disrupts various aspects of life. A substantial majority, approximately 90%, of individuals aged 18 to 29 years, utilize some form of social media. Statistics suggest that the global prevalence of social media addiction exceeds 210 million individuals. The study sought to assess …
Published in International Journal of Community Health Nursing And Practices · Vol. 2, Issue 1, 2024 · pp. 1–9 Read article