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26 articles for “Virus based drugs”
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Investigating the Impact of Viral Infections on Pharmacokinetics and Pharmacodynamics of Antiviral Drugs
Abstract: The emergence and re-emergence of viral infections pose significant challenges to public health, necessitating a comprehensive understanding of how these infections impact the pharmacokinetics and pharmacodynamics of antiviral drugs. This review explores the intricate interactions between viral pathophysiology and the pharmacological effects of antiviral agents. Factors such as viral replication dynamics, host immune responses, and the genetic variability of both viruses and hosts significantly influence drug absorption, distribution, metabolism, and …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 23–30 Read article
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Usage Pattern of Antibiotics for Management of Pneumonia
Abstract: AbstractPneumonia has evolved as one of the deadly infections globally and is a cause of concern all over the world. It is an air borne infection affecting the alveoli of the lungs and is caused by virus, bacteria, fungus etc. Antibiotic therapy is the most commonly available therapy in cases of pneumonia. Hence analysis of prescribing pattern of narrow and broad-spectrum antibiotics in pneumonia patients is essential for better treatment …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 10, Issue 2, 2020 · pp. 15–19 Read article
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Role of Healthcare Management in Pandemic of COVID-19
Abstract: COVID-19 was first reported on December 19, 2019, in the city of Wuhan Hubei in China. It has since spread to more than 210 countries and regions. This severe acute respiratory syndrome is spread over by the coronavirus with trouble in breathing and flu-like symptoms. The disease caused by virus was called COVID-19. Over 2.2 million people worldwide have died. The United States is the most affected country with 0.7 …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 10, Issue 1, 2021 · pp. 1–6 Read article
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Sequence analysis, DNA Methylation and Molecular therapy of Oral cancer caused by Human Papilloma Virus
Abstract: DNA methylations with oral cancer are been associated with high-risk Human Papillomavirus (HPV) and Epstein-Barr Virus (EBV) onco-proteins interactions may cooperate to increase disease severity. The work focused on human papillomavirus strain 16, a high-risk, sexually transmitted responsible for 95% of all cervical cancers and a large portion of oropharyngeal cancers. The prediction of genes from has shown seven genes from HPV16 strain. Based on gene identification studies, Human papilloma …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 2, 2026 · pp. 1–9 Read article
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Targeting Papain-Like Protease of Re-Emerging Coronaviruses
Abstract: Re-emerging Corona viruses (CoVs), including SARS-CoV (S-CoVs), and SARS-CoV-2 (S-CoV-2), continue to pose a global health threat due to their high mutation rates, zoonotic spillover potential, and capacity for immune evasion. The global pandemic of year 2019, caused by S-CoV-2, has highlighted the importance for robust antiviral strategies beyond vaccines and RNA polymerase or main protease inhibitors, which are susceptible to resistance. One promising therapeutic target is the S-CoV-2 papain-like …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 3, 2025 · pp. 46–62 Read article
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Stavudine Lamivudine Efavirenz Combination Therapy for Treatment of HIV Infection in Tertiary Care Hospital - A Retrospective Observational Study
Abstract: Highly Active Antiretroviral Therapy has transformed human immunodeficiency virus (HIV) infection into a chronic manageable disease. Compliance is the biggest challenge in low and middle income country like India where social and religious agenda play an important role. Efavirenz based HAART is current standard of care in management of HIV infected patients. The objective of the present study was to know efficacy of combination regimen of stavudine, lamivudine and efavirenz …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 4, Issue 1, 2014 · pp. 17–22 Read article