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58 articles for “Randomized control trials”
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Effectiveness of Video-assisted Teaching on Anxiety Related to Labor Process and Preparation for Labor Among the Primigravida Mothers Attending Antenatal OPD at GMCH-32 Chandigarh
Abstract: Aims and background: A randomized control trial to assess the effectiveness of video-assisted teaching on anxiety related to labor process and preparation for labor among primigravida mothers attending antenatal OPD of GMCH-32, Chandigarh, was carried out in full compliance with ethical standards laid down by the Research and Ethical Committee of GMCH-32, Chandigarh. Method: A systematic random sampling technique was used to select 80 subjects, 40 each in control and …
Published in International Journal of Midwifery Nursing And Practices · Vol. 2, Issue 1, 2024 · pp. 9–13 Read article
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A study to assess the effect of nature-based sound therapy during weaning among Mechanically Ventilated patients admitted in intensive care units of a selected tertiary care hospital Ludhiana, Punjab
Abstract: Weaning is a gradual transition from full invasive ventilatory support to spontaneous ventilation with minimal support. This conducted to assess the effect of nature-based sound therapy among Mechanically Ventilated Patients admitted in Intensive Care units. An experimental design (randomized controlled trial) was used to assess the effect of nature-based sound therapy during weaning among Mechanically Ventilated patients.30 patients were drawn from the target population by using convenience sampling technique and …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 1, 2024 · pp. 44–48 Read article
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Comparative Study of Analgesic Effect of Intrathecal Magnesium Sulphate, Clonidine and Dexmedetomidine as an Adjunct to Intrathecal Bupivacaine in Spinal Anesthesia for Lower Limb Orthopaedic Surgeries
Abstract: This prospective double blind, randomized controlled trial study was undertaken to compare the onset and duration of analgesia with the intrathecal bupivacaine and its combination with either clonidine or magnesium sulphate or dexmedetomidine, to establish the ideal combination of drug with least side effects. The study included 80 patients between age group 20–60 years of ASA grade I & II, scheduled for orthopaedic lower limb surgery. Patients were randomly assigned …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 3, Issue 3, 2014 · pp. 13–18 Read article
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Comparative Efficacy and Safety of Safinamide and Rasagiline in the Treatment of Parkinson’s Disease: A Meta-Analysis and Systematic Review
Abstract: Background: Recent studies have suggested Rasagiline and Safinamide monotherapy as potential management options for Parkinson’s disease. Parkinson’s disease, a neurological disorder characterized by tremors and movement difficulties, necessitates treatments aimed at managing clinical symptoms. Levodopa remains the primary effective treatment for Parkinson’s disease symptoms; however, its long-term use often leads to motor complications in many patients. Additional therapeutic drugs, such as dopamine agonists and monoamine oxidase B inhibitors, including Safinamide …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 74–91 Read article
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Evaluating the Role of Apple Cider Vinegar in Managing Semaglutide-Induced Gastrointestinal Disturbances: A Systematic Review
Abstract: Background: Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, is highly effective in treating type 2 diabetes and obesity. However, its use is often associated with gastrointestinal side effects, including nausea, vomiting, and diarrhea, which may impact patient compliance. Objective: This systematic review aims to evaluate the evidence regarding the management of semaglutide-induced GI symptoms and assess the potential role of apple cider vinegar (ACV) as a complementary treatment. Methods: A …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 1, 2025 · pp. 25–31 Read article
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Advances in Total Knee Replacement: A Systematic Review of Clinical Outcomes and Complications
Abstract: Total Knee Replacement (TKR) is a widely used surgical intervention for patients with knee osteoarthritis and other degenerative knee disorders, offering significant improvements in pain relief, functional restoration, and quality of life. This systematic review synthesizes data from multiple clinical studies to evaluate the outcomes and complications associated with TKR. To find applicable research published in the last ten years, a thorough search of electronic databases was performed. Randomised controlled …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 1, 2024 · pp. 41–56 Read article
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Serum Magnesium, Iron, TIBC, and Hormonal Imbalances in Hypertensive Pregnant Women: A Comparative Study
Abstract: Pregnancy-induced hypertension (PIH), including gestational hypertension and preeclampsia, is a leading cause of maternal and fetal complications. The regulation of blood pressure and overall pregnancy health is influenced by micronutrients and hormones. This study aimed to evaluate serum magnesium, serum iron, total iron binding capacity (TIBC), thyroid profile, and quadruple marker levels in hypertensive pregnant women and compare them to normotensive controls. Methods: A total of 1056 hypertensive pregnant women …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 · pp. 41–45 Read article
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Electroconvulsive Therapy in the Management of Schizophrenia: A Systematic Review in Emergency Nursing Practice
Abstract: Electroconvulsive therapy (ECT) is a well-established treatment for various psychiatric disorders, including schizophrenia, particularly in cases where patients are resistant to conventional treatments. Schizophrenia, a chronic and severe psychiatric disorder, often presents with a combination of positive symptoms (such as hallucinations and delusions), negative symptoms (such as social withdrawal and emotional blunting), and cognitive impairments. While antipsychotic medications are the primary treatment, approximately 20–30% of individuals with schizophrenia do not …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 43–48 Read article
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GLP-1 Receptor Agonists: A Dual Therapeutic Strategy for the Management of Type 2 Diabetes Mellitus and Obesity
Abstract: For the treatment of obesity and type 2 diabetes mellitus (T2DM), glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have become a revolutionary class of pharmaceutical drugs. These drugs were first created as glucose-lowering treatments, but they have now shown other advantages, such as notable weight loss, better cardiovascular results, and general metabolic control. The objective of this narrative review is to assess the pharmacological mechanisms, clinical efficacy, safety profile, and therapeutic …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 69–75 Read article
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The Hidden Struggle: Premenstrual Depression its Impact on Women’s Health and Management Strategies: A Narrative Review.
Abstract: Background: Premenstrual depression, including Premenstrual Syndrome (PMS) and Premenstrual Dysphoric Disorder (PMDD), represents a significant yet underrecognized contributor to women’s mental health burden. Hormonal fluctuations during the luteal phase interact with neurotransmitter systems, particularly serotonin and GABA, leading to affective and somatic symptoms that impair daily functioning. Objective: This systematic review synthesizes evidence on the prevalence, pathophysiology, psychological impact, and management strategies of premenstrual depression among reproductive-aged women, with particular …
Published in International Journal of Nutritions · Vol. 3, Issue 1, 2026 · pp. 21–32 Read article
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Nomophobia and the Power of Mind-Body Practices: Path to Digital Detoxification
Abstract: The present study investigated how mindfulness and self-control can be enhanced through the ancient practices of Pranayama and meditation to reduce dependence on mobile devices. The present study was aimed to assess the impact of meditation and Pranayama practices on reducing screen time, improving mindfulness, and enhancing overall well-being among university students. The present study investigated the impact of meditation and Pranayama practices on individuals' screen time habits, focusing on …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 10, Issue 3, 2023 · pp. 17–25 Read article
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Game Intervention: An Innovative Teaching and Learning Strategy to Promote Oral Hygiene Among Pediatric Cancer Clients
Abstract: Background: Gaming is an educational strategy that facilitates visual alertness, increases attention span, and assists with memory and reasoning as well as reinforces a child’s learning in a stimulated and dynamic way. Purpose: To differentiate the game intervention and standard care on oral hygiene status among children suffering from cancer. Method: A Randomized control trial research approach is used in this study to evaluate and compare the effect of game …
Published in Research and Reviews: A Journal of Dentistry · Vol. 14, Issue 2, 2023 · pp. 21–30 Read article
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Effect of Ultrasound and Low Level Laser Therapy on Nerve Conduction Studies in Patients with Carpal Tunnel Syndrome
Abstract: Carpal tunnel syndrome is a common entrapment neuropathy resulting from median nerve compression with the symptoms of pain, numbness and tingling in the hand and fingers. There are many conservative treatment options available for carpal tunnel syndrome. Ultrasound and low level LASER therapy are found to be one of the effective conservative treatments. The purpose of this study is to find the effect of ultrasound and low level LASER therapy …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 3, Issue 2, 2013 · pp. 9–14 Read article
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Case Control Analysis on Neurodegeneration Disorders and Autism in Familial Context
Abstract: Neurodegenerative disorders such as Parkinson's and Alzheimer's co-occur with autism spectrum disorder (ASD), indicating shared genetic factors. Oxidative stress and inflammation play roles, with an elevated risk of Parkinson's and dementia in individuals with autism spectrum disorder. Antioxidant levels are linked to language and behaviour in autistic children. In the present study, a systematic review and meta-analysis was done following the PRISMA guidelines, reviewing English articles (2002- 2022) on familial …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 13, Issue 2, 2023 · pp. 31–39 Read article
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Novel plasma therapy for covid-19: A Perspective
Abstract: Coronavirus disease (COVID-19) is an induced disease caused by the coronavirus-19 that causes acute respiratory syndrome (SARS COVID-19). In the month of December 2019, the first case was recorded in Wuhan, China. No specific medications have yet been approved for their treatment; convalescent plasma therapy is projected to boost the survival rate. Early in the twentieth century, convalescent plasma therapy was developed. Convalescent plasma therapy is widely utilized around the …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 10, Issue 3, 2021 · pp. 30–34 Read article
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Impact of Pelvic-Floor Muscle Training on Stress Urinary Incontinence – A Narrative Review
Abstract: Background: Urinary incontinence (UI), characterized by the unintentional loss of urine, is a common health issue among women globally. Stress urinary incontinence (SUI) is the most frequently reported type and can adversely affect daily activities and overall well-being. Various contributing factors, including obesity, pregnancy, and advancing age, are associated with its occurrence. Pelvic-floor muscle training (PFMT) is commonly advocated as a primary conservative management strategy for SUI. Objective: To evaluate …
Published in Research and Reviews: A Journal of Health Professions · Vol. 16, Issue 2, 2026 · pp. 1–8 Read article
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An Analysis of Machine Learning Models for Early Cardiac Risk Stratification
Abstract: The paper shows an in-depth study of machine learning and artificial intelligence solutions to early cardiac risk stratification which has a crucial necessity because cardiovascular disease (CVD) prediction remains a significant issue that needs to be improved beyond the conventional risk score. Since CVD is the most serious disease killer in the world, claiming 17.9 million deaths every year, there is a strong need to get the most sophisticated predictive …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 13, Issue 2, 2026 Read article
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Breathing for Brains: Yoga's Cognitive Transformation in College Students
Abstract: This study investigates the potential cognitive-enhancing effects of meditation and pranayama practices in young adults aged 18–25. A randomized controlled trial was conducted, with one group undergoing a two-month, meditation and pranayama intervention, while the other served as a control with no intervention. Various physiological parameters were assessed, including blood pressure, pulse rate, lung capacity, and oxygen levels. The intervention group practiced mindfulness, Om meditation, focus meditation, body scan meditation, …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 13, Issue 3, 2023 · pp. 1–10 Read article
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Gingival Markers as a Tool for Predicting Orthodontic Treatment: A Systematic Review
Abstract: To assess gingival markers as a tool for predicting orthodontic treatment is the main aim of this study. There is a continuous search for methodologies to asses or diagnose the periodontal associated disease, thereby providing a quicker and scientifically proven treatment plan. Clinical evaluation and radiographic reports were the main means of detection of any pathology or disease involving periodontium and the alveolar bone around it. Over the passage of …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 12, Issue 3, 2022 · pp. 41–47 Read article
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Second Generation Platelet Rich Concentrates and Their Role in Periodontal Therapy: A Review
Abstract: Periodontal tissue regeneration has always been a challenge for the periodontists. Regeneration of lost tooth supporting structure by periodontitis is a primary goal of periodontal therapy. Platelet rich blood derivatives have been widely used in the field of dentistry. In recent years, platelet rich blood derivatives have gained more attention in periodontal regeneration. Platelet rich blood derivative which include platelet-rich plasma (PRP), platelet-rich fibrin (PRF), platelet-derived growth factors (PDGF), have …
Published in Research and Reviews: A Journal of Dentistry · Vol. 10, Issue 1, 2019 · pp. 24–30 Read article