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34 articles for “Fowler–Nordheim (FN)”
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Role of Transcription factor AP-1 in Breast carcinoma
Abstract: Breast cancer is a major health problem of today. Transcription factor is nothing but protein that is needed for transcription. Activator protein-1 (AP-1) is a transcription factor of complex oncogene proteins (Jun and Fos). Fos and Jun family participate in many cellular processes which includes proliferation, differentiation and carcinogenesis. Therefore, this study has been designed to study level of transcription factor AP-1 in breast carcinoma. The study was carried on …
Published in Research and Reviews: A Journal of Health Professions · Vol. 9, Issue 2, 2019 · pp. 22–28 Read article
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Chest Wall Tuberculosis: A Case Report
Abstract: Chest wall tuberculosis is a very rare form of tuberculosis. Its presentations often misguide the clinician for early diagnosis and produce a diagnostic dilemma. High index of suspicion and exposure to literature reports may be helpful for early diagnosis and treatment. Here, such a case of chest wall tuberculosis which was preliminary managed by many clinicians with variety of empirical diagnosis has been reported. Even the FNAC report from the …
Published in Research and Reviews : A Journal of Immunology · Vol. 4, Issue 3, 2014 · pp. 6–8 Read article
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Glutathione: Postoperative Study in Breast Carcinoma
Abstract: Breast cancer represents a significant problem in the world. Glutathione a tripeptide is found in all mammalian tissues. Thus any change in its synthesis or utilization can profoundly influence the redox status of cells. In this study blood sample was collected from 60 FNAC confirmed breast cancer patients (preoperative and postoperative three months) and 30 normal healthy controls for the estimation of glutathione. There was significant increase in glutathione in …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 7, Issue 1, 2018 · pp. 3–6 Read article
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Nitric Oxide Synthase (NOS) in Breast Carcinoma
Abstract: Breast cancer is the most alarming problem of the current time. Nitric oxide, a free radical gas is synthesized by isoenzymes called nitric oxide synthase. Nitric oxide synthase consists of three isoforms; Nitric oxide produced is cytotoxic which is known to inhibit the DNA synthesis causing its damage. Keeping this in mind, nitric oxide synthase was determined in breast cancer and normal breast tissue. For this tissue from 60 breast …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 7, Issue 1, 2018 · pp. 23–28 Read article
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A Case study of Parapharyngeal Space Tumor with Unusual Presentation
Abstract: Aim: To study and treat the parapharyngeal space tumors presenting with swelling on left side of neck. Result: presenting a case of 25 year old male with swelling on left side of neck, FNAC revealed the diagnosis of a pleomorphic adenoma of parapharyngeal space. Tumor was intraorally excised. HPR revealed pleomorphic adenoma which concluded the diagnosis of benign parapharyngeal tumor from deep lobe of parotid gland. Conclusion: Tumor of parapharyngeal …
Published in Research and Reviews : Journal of Surgery · Vol. 6, Issue 2, 2017 · pp. 16–21 Read article
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Giant Cell Tumour of Tendon Sheath in Thumb: A Case Report
Abstract: Giant cell tumor of the tendon sheath is the second most common tumor of the hand often referred to as xanthoma. Histologically these tumors are composed of multinucleated giant cells, polyhedral histiocytes, fibrosis and hemosiderin deposits. Marginal excision of giant cell tumor of the tendon sheath is the treatment of choice. We present a case of Xanthoma of flexor pollicis longus tendon that presented as single enlarging mass in volar …
Published in Research and Reviews : Journal of Surgery · Vol. 3, Issue 1, 2014 · pp. 30–32 Read article
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Spindle Cell Neoplasm of Left Supra Scapular Region: Rare Case
Abstract: One challenging feature of head and neck pathology is that a dizzying array of spindle cell lesions occurs here ranging all the way from reactive to malignant and very aggressive. Most SPN are overtly malignant, and the differential diagnosis then includes a number of different malignant spindle cell neoplasm. However, there are several benign or even non-neoplastic lesions that can sometimes be difficult to discern from SPN. The pathologic and …
Published in Research and Reviews : Journal of Surgery · Vol. 3, Issue 3, 2014 · pp. 13–15 Read article
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Breast Cancer at Community Level in Bangladesh
Abstract: Background: Breast cancer is an issue of gaining concern in Bangladesh that causes high mortality and morbidity. Lack of screening and surveillance programme contributes to this. Almost no baseline data were found in this issue, though Government of Bangladesh launched a breast cancer surveillance programme based on clinical breast examination (CBE). This research was an effort to produce some baseline data to strengthen the programme of Government of Bangladesh. Methods: …
Published in Research and Reviews : Journal of Surgery · Vol. 8, Issue 2, 2019 · pp. 4–7 Read article
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Giant Right Groin Leiomyoma Mimicking Inguinal/Femoral Hernia - Case Report
Abstract: Groin leiomyoma is a rare condition. Such presentation may lead to misinterpretation of inguinal or femoral hernia diagnosis. In case of incorrect diagnosis, there is a high risk for the development of intraoperative complications. Here we report a female patient who presented with a huge soft elastic sessile swelling of 20x25 cm size in the right groin region. The patient clinically had a total history of 9 yrs. Examination revealed …
Published in Research and Reviews : Journal of Surgery · Vol. 8, Issue 3, 2019 · pp. 23–25 Read article
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Fibonacci Cordial Labeling of Some Graphs
Abstract: An injective function f: V (G) → {F0, F1, F2, . . . , Fn+1}, where Fj is the jth Fibonacci number (j = 0, 1, . . . , n+1), is said to be Fibonacci cordial labeling if the induced function f ∗ : E(G) → {0, 1} defined by f ∗(uv) = (f (u) + f (v))(mod2) satisfies the condition |ef (0) − ef (1)| ≤ 1. A …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 5, Issue 1, 2018 · pp. 1–4 Read article
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Migratory Birds in Pakistan and Effects of Climate Change
Abstract: Nature has blessed us with so many beautiful creations. Everything in the universe is playing its productive part as part of a cycle which is essentially followed by all living beings. Changing weathers, warm summers, freezing colds, pleasing springs and withering autumns, all play an important and significant role in our lives. Birds’ migration is a common phenomenon which over a past decade has witnessed a momentous change in pattern …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 6, Issue 2, 2016 · pp. 15–18 Read article
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Thyroid Disorders in Regard to Aetiology, Clinical Patterns, Management
Abstract: Thyroid disorders are one of the important and common endocrine problems encountered in clinical and occupational practice in all age groups more frequently in women and in adult population. Amongst all the functional thyroid disorders, hypothyroidism is far more common than hyperthyroidism. Recognition of this condition at an early stage can delay the progression to overt disease. Appropriate use of biochemical test, i.e., thyroid function test can delineate practically all …
Published in Journal of Energy, Environment & Carbon Credits · Vol. 6, Issue 3, 2016 · pp. 34–42 Read article
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Superoxide Dismutase (SOD) in Breast Carcinoma
Abstract: Breast cancer is the leading problem around the world predominantly in developing parts. Oxidative stress plays a crucial role in carcinogenesis especially in breast carcinoma. Disbalance in free radical and antioxidants result in oxidative stress. Enzymes like Superoxide dismutase (SOD) are used as primary defence; they directly scavenge and inactivate reactive oxygen species (ROS). Keeping this in mind, this study has been designed to study SOD in breast carcinoma before …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 1, 2019 · pp. 94–98 Read article
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QSAR Studies of 3-(4-(3-(Substitutedphenyl) Acryloyl) Phenyl)-2-Substituted phenyl/Phenylthiazolidin-4-ones for Anticancer Activity
Abstract: Both, Chalcone and 4-thiazolidinone, are therapeutically significant organic moieties with anticancer activities. QSAR (Quantitative structure–activity relationship) studies of ten synthesized chalcone-thiazolidinone hybrids have been described for anticancer activity against three cancer cell lines: A-549 (Human lung adenocarcinoma), U-87 MG (Human glioblastoma cancer cells) and COLO-205 (Human colon cancer cells). The developed linear QSAR models have significant statistical quality showing good fitting ability and robustness. The Q2 and R2 values of …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 3, Issue 3, 2016 · pp. 16–22 Read article