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1958 articles for “Disc” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Illuminating the Frontier of Drug Discovery: Unleashing the Power of Bioinformatics for Unprecedented Breakthroughs
Abstract: It takes a long time and a lot of effort to discover and develop new drugs, which necessitates extensive study and testing. With the help of computational techniques and data analysis, bioinformatics has grown to be a potent tool for drug discovery in recent years, allowing researchers to find new drugs faster. In this review, we examine the role of bioinformatics in drug discovery, including the use of ligand- and …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 2, 2023 · pp. 1–10 Read article
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Intergenerational Trauma and Cultural Resilience: Exploring the Impact of Family Norms on Mental Health Disclosure
Abstract: This comprehensive review examines how intergenerational trauma and cultural resilience influence individuals' choices to disclose or conceal their mental health challenges in family contexts. This paper utilizes 50 peer-reviewed studies out of 80 in total from various cultural contexts, this paper explores how family norms, especially in collectivist cultures, impact the disclosure of mental health issues. This review paper uses a thematic analysis strategy, systematically integrating qualitative, quantitative, and mixed-method …
Published in International Journal of Behavioral Sciences · Vol. 2, Issue 2, 2025 · pp. 53–58 Read article
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Effect of Seat dimensions on operator discomfort while operating Forklifts
Abstract: AbstractThe objective of the study is to investigate the body discomfort sensed by the forklift operators in their operation with respect to seat dimensions and determine the discomfort level at various working shift intervals such as the start of the shift, morning break, before lunch, after lunch, afternoon break and end of the shift with the help of Corlett and Bishop’s method of body mapping. A total of 47 operators …
Published in Journal of Industrial Safety Engineering · Vol. 4, Issue 3, 2017 · pp. 24–36 Read article
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Oral versus Written Discourse in Adolescents and Young Adults: A Comparative Study
Abstract: Discourse may vary as a function of modality of presentation. Studies on oral and written discourse have shown mixed findings. The present study was carried out with the aim of comparing the relationship between conceptual unit and the output across oral and written modalities. The participants were divided into two groups based on their age. The first group (Group 1) comprised of young adults while the second group (Group 2) …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 10, Issue 1, 2020 · pp. 30–33 Read article
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A quasi experimental study on effect of sponge bath on reducing discomfort among post operative general surgery patients in a selected Hospital at Chandigarh 2011
Abstract: Background: Bathing is considered a necessary and therapeutic nursing intervention since it provides hygienic care for clients. Bathing removes sweat, oil, dirt and micro-organisms from the skin, assists in decreasing body odour and the potential for infection, stimulates circulation and provides clients with a refreshed and comforted feeling. Objective: To study the effect of sponge bath on reducing discomfort among post operative general surgery patients. Methods: Study was conducted on …
Published in Research and Reviews : Journal of Surgery · Vol. 6, Issue 2, 2017 · pp. 1–5 Read article
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Integration of Taguchi and MCDM Techniques for the Optimization of Experimental Parameters in Electrical Discharge Machining: A Research
Abstract: Electric discharge machining (EDM) represents a non-conventional approach to machining, particularly beneficial for processing hard-to-machine materials or components with high length-to-diameter ratios or intricate shapes. Widely employed across various industries such as automotive, chemical, aerospace, biomedical, and tool and die, EDM offers a unique method for achieving precise shapes and dimensions. Unlike traditional machining methods where form is attained through the interaction of the tool and workpiece, EDM operates without …
Published in Trends in Mechanical Engineering & Technology · Vol. 14, Issue 1, 2024 · pp. 6–14 Read article
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Engineering Perspectives: Thermal and Structural Examination of Disc Brakes for Light Vehicles
Abstract: The procedure of braking transforms the kinetic energy of a car into mechanical energy that needs to be released as heat. High temperatures may result from the frictional heat produced at the disc and pad interface during the braking phase. Frictional heat produced on the rotor surface can contribute to an excessive rise in temperature, which can have unfavorable effects including premature wear, brake fluid vaporization (BFV), thermally excited vibrations …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 1, Issue 2, 2023 · pp. 16–23 Read article
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Review on Computer-Aided Drug Design in RAS Inhibitor Discovery
Abstract: This review explores the utilization of computer-aided drug design (CADD) methodologies in the discovery of inhibitors targeting the RAS pathway, a pivotal signaling cascade implicated in various cancers. Through an extensive examination of computational tools, methodologies, challenges, and recent advancements, this review aims to provide insights into the role of CADD in accelerating RAS inhibitor discovery. The discovery of effective inhibitors targeting the RAS pathway is of paramount importance in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 7–14 Read article
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Computational Simulations in Drug Discovery: Modeling Protein Folding and Drug Binding
Abstract: Computational simulations have become essential tools in drug discovery, offering unprecedented insights into molecular behavior at the atomic level. These simulations, particularly in the domains of protein folding and drug binding, allow for the exploration of complex biological systems that are often difficult to study experimentally. Protein folding, a critical aspect of drug discovery, involves the transition of a polypeptide chain from an unfolded to a biologically active structure. Understanding …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 1, 2025 · pp. 23–29 Read article
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Predictive Factors of Long-Term Sobriety: A Post-Discharge Outcome Study in Mangalore, Goa, and Vasai (2019–2023)
Abstract: Relapse following discharge remains a major challenge in addiction recovery, even with structured treatment protocols in rehabilitation centers. This study examines post-discharge outcomes from Kripa Foundation’s rehabilitation centers in Mangalore, Goa, and Vasai over a five-year period (2019–2023). A total of 100 patients were categorized into four behavioural outcome groups: Clean (Sober), Relapsed, R.I.P. (Deceased), and Unknown. The study aimed to identify demographic and behavioural predictors of sustained sobriety post-discharge. …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 3, 2025 · pp. 29–44 Read article
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Green Medicines in Drug Discovery
Abstract: The process of finding new leads for medicines using natural products is challenging. It discusses bioactive composites generated from natural resources, including phytochemical analysis, characterization, and pharmacological investigation. The success of these resources in the process of discovering unique and effective pharmacological combinations that may help mortal coffers is the primary focus. Natural goods have long been employed as a source of medicinal compounds, and they have shown promising results. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 1, 2026 · pp. 32–48 Read article
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A New Computational Method for Dust and Gas Dynamics in Protoplanetary Discs
Abstract: The simultaneous evolution of dust and gas in protoplanetary discs regulates essential events in planet formation, such as dust accumulation, migration, and the initiation of gravitational instabilities. Nevertheless, precisely modelling this interaction continues to provide a significant computing problem owing to the extensive variety of spatial and temporal scales involved. In this study, we introduce an innovative computational framework for simulating dust-gas dynamics in protoplanetary discs, integrating a two-fluid hydrodynamical …
Published in International Journal of Universe · Vol. 1, Issue 2, 2025 · pp. 35–46 Read article
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Hybrid Braking System: Electromagnetic + Disc Braking
Abstract: The Hybrid Braking System combines electromagnetic braking and traditional disc braking to enhance vehicle safety, improve braking response, and reduce mechanical wear. This system integrates sensor fusion technologies, including ultrasonic and infrared sensors, to enable adaptive braking based on real-time road conditions. A PID-based control algorithm optimizes braking force distribution, ensuring a smooth and controlled deceleration. Additionally, the incorporation of regenerative braking allows for energy recovery, increasing vehicle efficiency and …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 4, Issue 1, 2026 · pp. 8–14 Read article
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Integration of Taguchi and MCDM Techniques for the Optimization of Experimental Parameters in Electrical Discharge Machining: A Research
Abstract: Electric discharge machining (EDM) represents a non-conventional approach to machining, particularly beneficial for processing hard-to-machine materials or components with high length-to-diameter ratios or intricate shapes. Widely employed across various industries such as automotive, chemical, aerospace, biomedical, and tool and die, EDM offers a unique method for achieving precise shapes and dimensions. Unlike traditional machining methods where form is attained through the interaction of the tool and workpiece, EDM operates without …
Published in Trends in Mechanical Engineering & Technology · Vol. 14, Issue 1, 2024 · pp. 6–14 Read article
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Perceived Joint Discomfort Rating in Neck and Back Movement away from Neutral in Sitting and Standing Posture
Abstract: The objectives of the study is to observe the effects of deviation from neutral position on the perceived joint discomfort rating in neck and back in sitting and standing position. It is an observational study. Subjects were recruited from Dolphin (P.G.) Institute of Biomedical and Natural Science, Dehradun. A total of 40 subjects were recruited for the study on the basis of inclusion and exclusion criteria after signing the informed …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 3, Issue 1, 2014 · pp. 13–23 Read article
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Perceived Joint Discomfort Rating in Neck and Back Movement away from Neutral in Sitting and Standing Posture
Abstract: The objectives of the study is to observe the effects of deviation from neutral position on the perceived joint discomfort rating in neck and back in sitting and standing position. It is an observational study. Subjects were recruited from Dolphin (P.G.) Institute of Biomedical and Natural Science, Dehradun. A total of 40 subjects were recruited for the study on the basis of inclusion and exclusion criteria after signing the informed …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 3, Issue 1, 2014 · pp. 13–23 Read article
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Electrical Discharge Machining for Precision Metal Working Industries
Abstract: EDM is called as Electrical Discharge Machining. Otherwise called as Spark Erosion Machining, Electro-Erosion Machining, Spark Machining, and Electro Discharge Machining. It is an unconventional machining process to machine hard metals and alloys. EDM has been a significant machining technique. The electrode, work piece materials, dielectric, and the range of pulse rate, current, and voltage make up the basic EDM process. The dielectric serves the following purposes: it transports removal …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 1, Issue 2, 2023 · pp. 7–11 Read article
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A Review on Anesthetic Drug Discovery with Computer Aided Drug Design
Abstract: In contemporary medicine, anaesthesia is essential for enabling surgical procedures, pain control, and patient comfort. Finding and creating safe and efficient anaesthetics is crucial to enhancing patient outcomes and developing the medical field. In this review, we provide a comprehensive overview of anesthetic drug discovery with a focus on the integration of computer-aided drug design (CADD) methodologies. Beginning with an exploration of anesthesia mechanisms and targets, we delve into the …
Published in International Journal of Antibiotics Read article
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A Study to Find the Relation Between School Bag Weight and Musculoskeletal Discomfort in School Going Children
Abstract: Background: School bags are one of the several forms of manual load carriage used by school children. Carrying school bags that exceed 10% of body weight can lead to heightened energy expenditure, causing increased forward lean of the neck and trunk, reduced lung capacity, and elevated cardio-respiratory measures. Musculoskeletal disorders (MSDs) are characterized by injuries or disorders affecting muscles, tendons, ligaments, cartilage, or spinal discs, as diagnosed by healthcare providers, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 2, 2024 · pp. 49–58 Read article
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Quantum-Fuzzy Tensor Operators and Uncertainty-Band Bifurcation for Symmetry-Preserving State Discrimination
Abstract: A tensor-operator framework is developed for fuzzy conjunction, fuzzy disjunction, and symmetry-preserving state discrimination in multi-qubit quantum systems. In this formulation, fuzzy membership and non-membership degrees are represented through expectations of effect operators acting on density matrices, providing a natural bridge between fuzzy logic and quantum measurement theory. Conjunction and disjunction operations are extended to the quantum domain via tensorised channels, constructed using projective measurements and unitary transformations, enabling logical …
Published in Emerging Trends in Symmetry · Vol. 2, Issue 1, 2026 · pp. 08–15 Read article