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365 articles for “medicinal uses and therapeutical uses”
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Screening of Pharmaceutically Significant Methioninase-Producing Fungi from the Satpura Range of Hoshangabad District and Its Large-Scale Production
Abstract: L-methioninase, an enzyme with notable anticancer properties, has emerged as a promising therapeutic agent due to its ability to selectively degrade methionine, a critical amino acid for the survival of methionine-dependent cancer cells. Methionine dependency, observed in many tumor cells, is a metabolic vulnerability that can be exploited for targeted cancer therapy. The Satpura Range in the Narmadapuram District, India, with its diverse microbial ecosystems, offers a rich reservoir for …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 2, 2025 · pp. 33–43 Read article
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Effect of Diarrhea at Admission on Time to Recovery in Treatment of Severe Acute Malnourished Children in Inpatient Therapeutic Feeding Program in Tigray Region, Ethiopia
Abstract: The mortality rate in inpatient settings remained unacceptably higher, 20–30% for marasmus and 50–60% for Kwashiorkor. This is due to inappropriate case management and co-morbidities mainly diarrhea. Despite, there was no study conducted to show the effect of diarrhea at admission on the length of time to recovery in the treatment of severe acute malnutrition among children aged 6–59 months and then there is little understanding about this issue. The …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 5, Issue 2, 2016 · pp. 25–40 Read article
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Clinical metabolomics: Useful insights, perspectives, and challenges.
Abstract: Metabolomics provides a comprehensive snapshot of smallmolecule intermediates and end products of cellular processes and thereby links genotype, environment, and phenotype in human disease . Over the last decade, advances in liquid chromatography–mass spectrometry (LC–MS) and nuclear magnetic resonance (NMR) spectroscopy have enabled high-throughput profiling of thousands of metabolites from microliter volumes of clinical samples . Clinical metabolomics is now emerging as a tool for disease diagnosis, risk prediction, therapeutic …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 29–37 Read article
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Leech Therapy: A Therapeutic GEM
Abstract: Leech, Genus Hirudo, and therapeutics species: Hirudo medicinalis is an amphibious worm, 10 cm in length and is usually black or brown in color. It has three jaws with about 100 tiny teeth and a posterior sucker. The leech’s salivary secretions contain many bioactive chemicals, among which the most potent is Hirudin. The therapy involves bite by the leech, followed by attachment for duration of 15 to 45 minutes. The …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 1, 2024 · pp. 27–30 Read article
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A Scientific Review on Phyto-pharmacological Properties of Moringa olifera Lam
Abstract: Moringa oleifera Lam. (Moringaceae) has been used since times to treat various health ailments. Different parts of plant have been used by traditional physicians. However, the dried entire fruit is more commonly used as Sehjana in Unani Medicine. Sehjana is a famous Indian drug used in a number of pathological conditions. Various parts of this plant act as cardiac and circulatory stimulants, possess anti-tumour, antipyretic, antiepileptic, anti-inflammatory, antiulcer, antispasmodic, diuretic, …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 7, Issue 3, 2020 · pp. 1–11 Read article
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A Study and Report on Impact of Pharmacovigilance and Drug Safety Monitoring Practices in Promotion of Rational Drug Usage in General Medicine Departments of Hospital
Abstract: The present study reports on impact of pharmacovigilance and drug safety monitoring practices in promotion of rational drug usage in General Medicine Department of ESI hospital with an objective of identification and reporting of Drug Related Problems. It is a prospective observational study & conducted for a period of six months from November 2020 to April 2021. A sample size of 120 patients were randomly opted for this study, out …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 8, Issue 2, 2023 · pp. 24–40 Read article
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Integrating Ayurveda in Infertility Management: A Case Study on Fimbrial Blockage
Abstract: Infertility significantly impacts a woman’s psychological and physical health, as well as that of her family. Fallopian tube blockage is one of the leading causes of female infertility, accounting for a substantial number of cases globally. Conventional medical approaches, including in vitro fertilization (IVF) and surgical procedures, often present barriers due to their high cost, invasive nature, and limited accessibility. Additionally, cultural, financial, and personal considerations can further restrict their …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 3, 2025 · pp. 12–19 Read article
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A Research Project on Identification and Reporting of Adverse Drug Reactions in General Medicine Ward of an ESI Hospital
Abstract: Aim: The study aims at identifying and reporting the adverse drug reactions (ADRs) in general medicine ward of an ESI hospital, Bangalore, Karnataka, India. Objective: Prescription study, analysis and prevention of medication-related problems (ADRs), identifying and minimizing medication-related problems, improving patient safety initiatives, improving the patient health-related outcomes, reducing work burden of physicians, and providing better therapy to large number of patients. Methodology: Study Design: It was a prospective and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 3, 2018 · pp. 9–14 Read article
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Personalized Therapy Using Drug Delivery Devices
Abstract: The persistent challenge in modern medicine lies in inter-patient heterogeneity, rendering standardized drug dosing protocols suboptimal for many chronic conditions. Traditional pharmacokinetics fail to account for real-time biological fluctuations, leading to cycles of ineffective treatment or dose-limiting toxicity. This paper explores the critical intersection of advanced drug delivery devices (DDDs) and personalized medicine, positioning these technologies as the vital link translating genomic and biological data into tangible, patient- specific interventions. …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 53–62 Read article
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A General Review of Mucuna Pruriens W.S.R to its effect on Parkinson’s Disease.
Abstract: Mucuna Pruriens is a very famous drug prescribed in classical ayurvedic science in various disorder of Nervous System including Kampavata .In Clinical Practice ,Physician used Levadopa as a Dopamine replacement agent in controlling bradykinetic symptoms apparent in Parkinson disease so used successfully in treatment of Parkinson disease.Kapikacchu(Mucuna Pruriens) is having Balya, Brimhanaha, Vrishya, and Vatahara properties and is a natural source of L-dopa. So, keeping in views of the degenerative …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 1, 2024 · pp. 1–6 Read article
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A Comprehensive Review on Ethnomedicinal Uses of Fishes in Asia
Abstract: In Asia, fish hold a multifaceted role as crucial dietary and economic resources, cultural symbols, and traditional ethnomedicine remedies. With over 4,000 known freshwater and marine fish species in Asian waters, these aquatic creatures feature prominently in the region's diverse ethnomedical traditions. The continent's numerous ethnic groups, each with unique indigenous medical practices, often rely on traditional ethnomedicine due to limited access to modern allopathic healthcare. The paper delves into …
Published in Journal of Catalyst & Catalysis · Vol. 10, Issue 3, 2023 · pp. 24–28 Read article
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Phytochemical Evaluation in Various Leaf Extracts of Wild Bhendi
Abstract: The vast diversity of natural products have been used for combating human diseases for thousands of years, since they exhibit a wide range of biological properties that can be exploited for medical application. The present study was carried out to analyse the preliminary phytochemical constituents in various solvent extract of wild Bhendi. The results revealed the presence of medicinally active compounds such as alkaloids, tannin, phenol, saponin, flavonoids and glycosides …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 11, Issue 3, 2021 · pp. 23–28 Read article
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Computational Exploration of Bhrijraj-derived Phytochemicals as Potential Anti-inflammatory Agents: A Molecular Docking Study with Cyclooxygenase-II Complex
Abstract: The molecular docking analysis was meticulously conducted using state-of-the-art computational tools, notably Chimera and Python. These tools were employed to unravel the complex interactions between the identified phytochemicals from Bhrijraj and the target protein, COX-II. The 3D structures of the phytochemicals were prepared with precision using ChemSketch, ensuring accuracy in the subsequent molecular docking simulations. This rigorous approach enhances the reliability and validity of the findings. This research aims to …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 31–37 Read article
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Novel 1,3,4-Thiadiazole Derivatives: Design, Synthesis, Characterization and Anticancer Evaluation – A Review
Abstract: Cancer remains one of the leading causes of mortality worldwide despite significant advances in diagnosis and treatment. The clinical usefulness of many anticancer drugs is often restricted by toxicity, poor selectivity, and the emergence of drug resistance. These limitations have encouraged the search for novel heterocyclic compounds with improved therapeutic efficacy and safety. Among these, the 1,3,4-thiadiazole scaffold has gained considerable attention because of its favorable physicochemical characteristics, metabolic stability, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 · pp. 42–49 Read article
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Uttarabasti in Female Infertility: A Retrospective Analysis of Clinical Outcomes and Safety Profile
Abstract: Background: Uttarabasti (UB) is a specialized Panchakarma procedure involving intrauterine instillation of medicated Sneha, classically indicated in Yonivyapad and Vandhyatwa. It facilitates targeted local drug delivery, bypassing gastrointestinal metabolism and enabling direct therapeutic action at the uterine level. In Ayurvedic understanding, UB achieves Garbhashaya Shuddhi and Apana Vata Anulomana — the two primary pathological corrections considered essential in Vandhyatwa. Infertility affects an estimated 10–15% of couples globally, with a substantial …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 2, 2026 · pp. 1–14 Read article
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A Review Article on Insect Antimicrobial Peptides: From Innate Immunity to Therapeutic Drug Leads
Abstract: Antimicrobial resistance to existing antibiotics is increasing, and the emergence of truly new classes of antibacterials is rare. Insects exposed to high pathogen densities for hundreds of millions of years depend in part on a rapid, inducible innate immune system that uses antimicrobial peptides (AMPs). These are small, typically cationic, amphipathic peptides mostly produced by the fat body and hemocytes and released in the hemolymph within a few hours of …
Published in International Journal of Insects · Vol. 3, Issue 2, 2026 Read article
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Exploring the Botanical and Pharmacological Significance of Aristolochia rotunda Linn (Zarawand Mudahraj): Traditional Uses, Habitat, and Bioactive Potential
Abstract: The plant Aristolochia rotunada Linn (Zarawand Mudahraj) is a member of the Aristolochiaceae family. Its rhizomes are the most valuable portion utilised in the pharmaceutical industry, mostly because of their abundance in bioactive compounds. The medicinal plant Aristolochia rotunda Linn exhibits a spectrum of pharmacological activities essential for combating hyper-uricaemia-induced inflammation. Its anti-inflammatory effects are mediated by inhibiting TNF-α, IL-1β, IL-8, and NF-κB p65 protein expression, crucial in synovial tissue. …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 2, 2024 · pp. 33–39 Read article
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Chemical Preparation Methods of Nano Material with their Applications
Abstract: Scientists were not satisfied with the diagnosis, exploration, injection and imaging through modern medical nanotechnology, but they were also able through this technology to activate smart microscopic bombs that target the cancer cell and detonate it, killing the cancer cells. This technology was tested on laboratory mice and achieved great success. Nanotechnology is the technology of the future, not only in the medical and therapeutic aspect, but also in everything …
Published in Journal of Petroleum Engineering & Technology · Vol. 14, Issue 2, 2024 · pp. 1–9 Read article
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Chemical Preparation Methods of Nano Material with their Applications
Abstract: Scientists were not satisfied with the diagnosis, exploration, injection and imaging through modern medical nanotechnology, but they were also able through this technology to activate smart microscopic bombs that target the cancer cell and detonate it, killing the cancer cells. This technology was tested on laboratory mice and achieved great success. Nanotechnology is the technology of the future, not only in the medical and therapeutic aspect, but also in everything …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 2, 2024 · pp. 1–9 Read article
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Exploring Azadirachta indica’s Potential to Combat Visceral Leishmaniasis Through GP63 Inhibition
Abstract: Objectives: Millions of people worldwide suffer from the parasite disease visceral leishmaniasis. Determine the naturally occurring active ingredients in Azadirachta indica, which are employed as a disease-prevention agent and have several uses in medicine. To choose the best ligand to use as a medication, absorption, distribution, metabolism, and excretion (ADME) studies and molecular docking are employed. Methods: To obtain the GP63 protein, the Protein Data Bank (PDB) database was accessed. …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 1–12 Read article