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349 articles for “amines”
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Physicochemical, Biochemical and Microbiological Characterization of Green and Black Tea during Storage in Different Packaging Materials
Abstract: The storage of tea is an important endeavor for tea industry. The appealing characteristics of this beverage are its aroma, taste, color as well as its antioxidant and antimicrobial qualities. The different manufacturing strategies for black and green tea affect the shelf life of different types of commercially available tea varieties. Different types of packaging alter the quality parameters of different tea clones. The quality parameters are assessed according to …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 6, Issue 3, 2016 · pp. 5–30 Read article
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Nanostructured TiO2 Prepared Through Sol–Gel Method Enhances the Activity of Antibiotics against Gram Positive Bacteria
Abstract: The synthesis and bioactivity of titanium dioxide (TiO2) nanoparticles has been extensively studied. However, the antibacterial activity of TiO2 individually or in combination with different antibiotics has not been demonstrated. TiO2 was prepared by sol–gel process using precursor Titanium (IV) Chloride (TiCl4) and concentrated sulfuric acid in 4 h of calcinations at 550 °C and the enhancement effect of TiO2 nanoparticle on the antibacterial activity of different antibiotics was evaluated …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 2, Issue 1, 2012 · pp. 6–12 Read article
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Patterning of Carbon Nanotubes on Silicon Wafer Using Self-Assembly Techniques
Abstract: Nanotechnology is an emerging technology that enables scientists to develop new materials and products at the molecular level. A carbon nanotube (CNT) is a rolled sheet of carbon atoms, coaxially arranged in cylindrical shape. Single-walled CNTs are ideal quantum systems for exploring basic science in one dimension. To find use in electronics, single-walled CNTs need to be efficiently separated by electronic type and aligned to ensure optimal and reproducible electronic …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 5, Issue 2, 2015 · pp. 6–15 Read article
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Homology Modeling and in silico Characterization of a Hypothetical Protein of Arabidopsis lyrata ssp. Lyrata
Abstract: Arabidopsis lyrata, a plant belonging to brassicaceae, is a model organism for studying evolutionary and ecological genetics. Most of the proteins of this plant have remained uncharacterized and their functional roles are still to be elucidated. In this investigation, we have attempted to characterize one such hypothetical protein in terms of its physico-chemical properties, secondary and tertiary structure features by in silico study. The protein was classified under glycoside hydrolase …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 3, Issue 2, 2013 · pp. 1–5 Read article
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Production of Bioflocculants from Bacillus subtilis-2162 and Determination of Its Flocculating Activity on Heavy Metal Chromium
Abstract: The bioflocculant production potential of Bacillus subtilis-2162 was evaluated using standard methods. The bacteria produced an extracellular bioflocculant. Culture conditions for optimal production of the bioflocculants include: glucose and sucrose as carbon sources; multiple + 2 nitrogen sources including: ammonium sulfate and yeast extract; Ca+2 as sole cation source; and initial medium of pH 7. Characterization of the pure bioflocculants revealed that it is thermostable. Hydroxyl, carboxyl and amino groups …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 3, Issue 3, 2013 · pp. 12–18 Read article
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Structural Analyses of SoxY and SoxZ Proteins from Epsilonproteobacterium Sulfurimonas denitrificans: A Structural Bioinformatics Approach
Abstract: Abstract:Molecular level participation of epsilonproteobacteria for the global sulfur oxidation phenomena is an essential zone to be indulged with. Epsilonproteobacteria aids in the microbial sulfur metabolism both at and beneath the seafloor. For the recycling of the inorganic sulfur compounds, microbial redox reactions are one of the responsible and most important reactions to maintain the environmental sulfur balance. These reactions are carried out by phylogenetically diverse sets of microorganisms. The …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 5, Issue 1, 2015 · pp. 35–44 Read article
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3D-QSAR and Molecular Docking Studies of Triazol-Cycloalkanol Derivatives Used as Potent 3-Dehydroquinase II Inhibitors Against Mycobacterium tuberculosis
Abstract: Tuberculosis is a life threatening infectious disease caused by gram positive bacteria mycobacterium tuberculosis. Emergence of drug resistance, multi drug resistance and extensively drug resistance strain of mycobacterium make the situation more worst. It increases the mortality rate of tuberculosis patient, time duration and cost of treatment. Various inhibitors and drug molecules are designed to combat this fatal disease. Enzymes of shikimate pathway are responsible for production of essential amino …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 5, Issue 3, 2015 · pp. 18–28 Read article
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Stress: The Negative Modulator of NGF
Abstract: Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin-top:0in; mso-para-margin-right:0in; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0in; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} Depression is associated with deficiencies in mono-aminergic transmitters and possibly neurotrophins. Stress-induced helplessness in rodents constitutes a well defined model to investigate neurobiological mechanisms of …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 1, Issue 2, 2011 · pp. 1–7 Read article
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Study on Preparation and Characterization of Ultrahigh Molecular Weight Polyethylene Nanocomposites Filled with ZnO Nanoparticles
Abstract: In order to create a completely flexible designed composite that makes it simpler to exhibit ideal mechanical and chemical properties, nano metal oxides are added to polymers as reinforcement. Polymer blends represent a crucial area in the management of innovative materials that outperform net polymers in terms of characteristics. Polymer mixes can provide components with lasting beneficial qualities, as opposed to what is possible with a single polymer equivalent. This …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 12, Issue 3, 2022 · pp. 1–11 Read article
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A Comparative in silico Study of the Glucose Transporters Predicts Ubiquitination of the Transporters at the C-Terminal End
Abstract: Glucose Transporters are a family of membrane spanning proteins that transports glucose from exterior of the cell to the interior of the cell through the plasma membrane. There are 14 glucose transporters known till now. Although the transporters belong to the same family but not all function in glucose transport. They are different from each other in primary amino acid sequence. However, there is similarity in the secondary as well …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 5, Issue 2, 2018 · pp. 15–24 Read article
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Computational Investigation of nsSNPs of PRSS1 Gene
Abstract: This research is done for the prioritizing of SNPs of a gene PRSS1 causing hereditary pancreatitis. In this analysis, the authors found out some nsSNPs as less stable, deleterious, probably damaging retain high risk score. It was also predicted that SIFT is fast SNPs server with comparison of PolyPhen2. By Doing its energy calculation and stability prediction, we can also determine the stability of mutant protein, that is ok whether …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 1, Issue 1, 2014 · pp. 15–22 Read article
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Identification of Specificity Determining Positions through Phylogenetic Studies and Molecular Modeling of ICP27 as a Drug Target of Herpes Simplex Virus-1
Abstract: An ever-growing effort to apply computational power to the combined chemical and biological space in order to streamline drug discovery, design, development and optimization can be achieved through computational approaches. Herpes simplex is an infection that is caused by a herpes simplex virus (HSV), and is one of the most common human infections transmissible to a body site. Infection with HSV can result in several diseases ranging from apparent infections …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 2, Issue 1, 2015 · pp. 32–43 Read article
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Methodologies for in silico and in vitro Test of Biphenylalanine Compounds as Potential HIV-1 gp120 Attachment Inhibitors
Abstract: We postulate that biphenylalanine and its derivatives are propitious candidates to inhibit the binding of HIV-gp120 to CD4 T-cell. Many biphenylalanine derivatives are synthesized chemically and also prevailing in nature. We have proposed atom- and bond-based 2D TOMOCOMD-CARDD approach to identify the best derivative. Moreover, according to our proposition, the principal law simulated from in silico interaction of gp120 with CD4 can be tested by ELISA in vitro. Furthermore, the …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 2, Issue 3, 2015 · pp. 38–42 Read article
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A Review on Protein Structure Prediction
Abstract: Protein structure prediction is the inference of the three-dimensional structure of a protein from its amino acid sequence. The prediction of folding and secondary and tertiary structure from its primary structure. Structure prediction is fundamentally different from the inverse problem of protein design. Protein structure prediction is one of the most important goals pursued by bioinformatics and theoretical chemistry. It is highly important in medicine and biotechnology. Every two years, …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 3, Issue 2, 2016 · pp. 1–7 Read article
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A Method of Universal Primer Design for The Detection of Diverged CTX-M Beta-Lactamases in Multi-Drug Resistant Superbugs
Abstract: Complexity of many diverged β-lactamases in common multi-drug resistant bacteria has reached very high level. We found >40% of common bacteria in Kolkata water bodies were ampicillin resistant and reported clinical isolates were >95% ampicillin resistant worldwide. More than twenty unique sequence classes of β-lactamases were known to cause MDR inactivating penicillin, cephalosporin and carbapenem drugs. Further, there are other diverged MDR genes like drug efflux genes (acrAB, mexAB-EF, tetA), …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 9, Issue 2, 2019 · pp. 1–10 Read article
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In silico Screening of Some Natural Sesquiterpenes Against Diverse Therapeutic Targets: A Multitargeted Approach
Abstract: The present research was rational in-silico based exploration of other significantly essential pharmacological potentials of the existing natural sesquiterpenes by using the Schrodinger software which is already known to scientific community owing to their anticancer and antibacterial potentials. The sesquiterpenes have been explored for possible therapeutic excellence by screening against Lipoxygenase-5 (anti-inflammatory), Cycloxygenase-2 (anti-inflammatory), Dipeptidyl peptidase (antidiabetic), Cyclin-Dependent Kinase-5 (anticancer), Angiotensin-1 Converting Enzyme (antihypertensive), and Protein kinase C (anticancer). The …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 6, Issue 2, 2019 · pp. 10–15 Read article
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Molecular Docking Approach on Thiazolidinedione Analogs as HIV-1-RT Inhibitors
Abstract: Potentially life threatening condition due to chronic syndrome caused by human immunodeficiency virus (HIV) is known as Acquired immunodeficiency syndrome(AIDS).Virus weakens the immune system of human being and body’s ability to fight against the organism, thereby causing the disease. When a person becomes infected with HIV, the virus attacks and weakens the immune system. In the given study, molecular docking study was performed on 30polysubstitutedThiazolidinedione (TZD) analogs as HIV-1 reverse …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 7, Issue 1, 2020 · pp. 1–6 Read article
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In Silico Identification of Small Molecules as Novel Coronavirus Protease Enzyme Inhibitors
Abstract: AbstractThe novel corona virus 2019 (COVID-19) is one of the global threats to the human civilization as it causes serious respiratory infection and multi-organ failure. Because of the absence of appropriate treatment protocol for 2019 novel corona virus, different methodologies are being tried in China, including drug repurposing. Recent discovery revealed the structure of novel corona virus main protease enzyme (Mpro) containing HIS41 and CYS145 amino acid residues present in …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 7, Issue 2, 2020 · pp. 33–43 Read article
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A Molecular Docking Approach for Unlocking the Potential of Bryophyllum peltatum Phytochemicals for Targeting Multiple Proteins in Mumps Treatment
Abstract: Objective: The Mumps virus is the source of the infectious illness mumps. It affects the parotid glands that make saliva. Swelling of this gland can cause severe pain in an individual. Finding the ADME qualities of several B. peltatum phytochemicals and determining which of these compounds may have the ability to prevent the mumps disease are the main objective of this investigation. Methods: The structure of Hemagglutinin-neuraminidase (HN) protein, was …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 13, Issue 1, 2023 · pp. 18–27 Read article
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Understanding the Molecular Mechanisms of Proteases in Bioprocessing: A Review on the Future of the Food Industry
Abstract: Proteases are enzymes that break down proteins through peptide bond catalysis. A protease is a single polypeptide chain of some 250 amino acids and is devoid of sulfhydryl groups. The COOH-terminal tryptic peptide of the protease molecule contains some 43 residues. Because of this unique structure and mechanism, they play a crucial role in the Bioprocessing industry, especially in food processing applications. Herein, the sources of proteases are discussed as …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 13, Issue 2, 2023 · pp. 17–25 Read article