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216 articles for “Insulin/IGF1-AKT-mTOR”
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Influence of Methanolic Extractives of Prepupal Stages of Black Soldier, Hermetia Illucens L. (Diptera: Stratiomyidae) on the Biochemical Parameters of Serum and Liver in the DMBA Induced Toxicity in Norwegian Rat, Rattus Norvegicus (L)
Abstract: The larvae of Black soldier fly (BSF), Hermetia illucens L., are reducing the environmental pollution through utilization of organic waste for their development on organic wastes and converting the organic waste into protein and fat rich biomass. Health promoting potentials of black soldier fly derived proteins as ingredient of diet appears to be crucial need of modern days. In present attempt, forty Norwegian Rats were utilized as experimental animals. The …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 12, Issue 3, 2021 · pp. 1–19 Read article
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Current and Future Prospects of Colostrum—Indian Ethnic Food Supplement
Abstract: Traditional foods of India are called as ‘Functional Foods’ because they contain components such as body healing components, dietary fibres and growth promoters. Colostrum is the first secretion from mammary gland of an animal after parturition, which contains high amount of many nutrients such as proteins, vitamins, minerals and biologically active substances like immunoglobulins, enzymes, hormones and growth factors. This physicochemical composition makes it highly useful food substance as nutraceuticals …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 5, Issue 3, 2016 · pp. 23–28 Read article
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Effect of Kitchen Waste Compost and Vermicompost in Combination with Chemical Fertilizer on the Production of Capsicum
Abstract: A study was carried out at the research field of the Horticulture Research Centre (HRC), Regional Agricultural Research Station (RARS), Bangladesh Agricultural Research Institute (BARI), Jamalpur, Bangladesh during October 2013 to April 2014 to develop standard production method of capsicum under GAP. BARI Mistimorich-1 was used in the study. Eight treatments were constructed with the fully matured compost for each evaluation, these were, T1=Recommended dose of Chemical fertilizers (RD), T2= …
Published in Research & Reviews : Journal of Botany · Vol. 8, Issue 2, 2019 · pp. 7–15 Read article
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A Review on Psidium Guajava
Abstract: Psidium guajava is an evergreen shrub belongs to Myrtaceae family and commonly known as guava. It contains phenolic compounds and acts as anti-oxidant properties as well as immunostimulant. It has a higher number of vitamins and minerals. Every part of this plant contains various phytochemicals like quercetin, rutin, kaempferol, gallic acid, epicatechin, ursolic acid, glucosides, guavanoic acid, guava coumaric acid, saponins, terpenoids are present. It shows various pharmacological activities like …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 10, Issue 3, 2021 · pp. 9–14 Read article
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TRACING PLANT POTENTIAL FOR CONTROLLING DIABETES: A COMPREHENSIVE STUDY
Abstract: Diabetes mellitus is a chronic metabolic non- communicable condition characterized with elevated or raised blood sugar or glucose levels for a prolonged period of time. The high level of blood sugar leads to development of specific symptoms like polyuria, polydipsia and polyphagia. The other symptoms include abnormal weight loss, fatigue, poor wound healing, infections, altered mental state and blurry vision. Exploring alternative treatments for diabetes, particularly those derived from medicinal …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 12, Issue 3, 2023 · pp. 34–41 Read article
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Evolution of Cancer Biomarker and its Therapeutic Drug
Abstract: The trend to develop personalized medicine in targeting the defective genes/proteins and its pathways have become a promising approach with a significant success rate seen so far. The causes of cancer vary from person to person. Mutation in a cancer-associated gene or causative gene such as EGFR, VEGF, mTOR etc will cause cancer and later metastasis but treatment has to be given by identifying the specific marker and targeting the …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 3, 2019 · pp. 15–27 Read article
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The Significance and Correlation of Biochemical Parameters-related to Bone Diseases
Abstract: The chemical composition, mass and property of bones are controlled by various factors which include decreased mineral intake or absorption, defects in Vitamin D absorption or activation. Bone diseases are also influenced by growth factors, estrogen, testosterone, insulin, Parathyroid, Thyroid, and Cortisol hormone. Our study handles various human blood and urine samples ranging between the ages of 25–50 years for the above mentioned parameters which include calcium, alkaline phosphatases, phosphorous, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 1, 2019 · pp. 33–36 Read article
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Safety evaluation of Maghz-e-Jamun (Eugenia jambolana) in Prediabetes - A Randomized Placebo Controlled Study
Abstract: Objective: to evaluate the safety of Unani drug Maghz-e-Jamun(Eugenia jambolana) in Prediabetes. Research design and methods: It was randomized, single blind, placebo-controlled study randomly assigned to 52 prediabetic patients (diagnosed according to ADA classification) in the test and control group. Maghz-e-Jamun (Eugenia jambulana) powder 4.5 g was filled in 6 capsules, 3 capsules were administered orally twice a day in the test group for 12 weeks. While placebo prepared with …
Published in Research & Reviews : Journal of Herbal Science · Vol. 8, Issue 2, 2019 · pp. 19–27 Read article
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Case Study: A Patient with Uncontrolled Type 2 Diabetes and Carbuncle in Thigh Whose Diabetes is Managed by Ayurvedic Intervention
Abstract: Background: Diabetes mellitus is a global pandemic with substantial public health implications. It is a well-known multifactorial metabolic condition defined by unusually high blood glucose levels caused by a shortage of insulin, either absolute or relative. Type-2 diabetes is the most common type of diabetes, accounting for 90% of all diabetics. Carbuncle is a rare skin and soft tissue infection that primarily affects uncontrolled diabetics. Presentation of the Case: A …
Published in Research & Reviews : Journal of Herbal Science · Vol. 10, Issue 3, 2021 · pp. 8–13 Read article
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Role of Ahara and Aushadha Mentioned in “Prameha Chikitsa Adhyaya” of Charak Samhita in Management of Agni with Special Reference to Kaphaja Prameha
Abstract: In Ayurveda health is dependent mainly on Equilibrium of Dosha, Agni, Dhatu and Proper function of Mala. Agni is the only factor in life, and when it disappears, it causes death. Keeping Agni in good condition promotes long life. Jatharagni is divided into four separate states. Sama (well-maintained and regular), Manda (weak or less powered), Teekshna (intenese), and Vishama (irregular) states. Samagni is the only one of Agni's four states …
Published in Research & Reviews : Journal of Herbal Science · Vol. 11, Issue 3, 2022 · pp. 40–48 Read article
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Therapeutic Effects of Metformin on Cancer: A Possible Option in Cancer Chemotherapy
Abstract: Metformin is being used for an elongated period of an antidiabetic medicine for type 2 diabetes. It is used moreover as a monotherapy or in mixture with additional antidiabetic medications. The drug derived into importance in diabetes and other circumstances with cardiovascular risk after the landmark study of 1995 by the United Kingdom Prospective Diabetes Study which highlighted its reputation. The usage of metformin, the usually given drug for type …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 8, Issue 1, 2023 · pp. 46–68 Read article
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A Review Article on Obesity: Classification, Biomarkers, Prevention and Treatment
Abstract: Obesity is a complicated condition characterised by an excess of body fat. According to the World Health Organization (WHO) and the National Institutes of Health, a person is overweight if their BMI is between 25.0 and 29.91 kg / m2, and obese if their BMI is greater than 30.0 kg / m2. Drugs such as psychiatric pharmaceuticals, diabetic therapies, antihypertensives, contraceptives, steroid hormones, antihistamines, and protease inhibitors, are linked to …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 9, Issue 3, 2022 · pp. 11–22 Read article
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In vitro and in vivo Anti-Oxidant and Anti-Diabetic Evaluation of cladodes Crude Extract and Solvent fractions of Opuntia elatior mill (Cactaceae)
Abstract: Objective: Ariel part of Opuntia elatior (Cactaceae) has been used in folklare remedies to treat diabetes in America, Mexico and India. However, the anti-diabetic potential of cladodes of this medicinal plant is not scientifically validated and authenticated. The present study aimed to evaluate in vitro and in vivo anti-oxidant and anti-diabetic potential of methanol extracts and solvent fractions of O. elatior cladodes. Methods: Phytochemical analysis performed according to standard procedure. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 2, 2025 · pp. 77–88 Read article
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Transethosomes: Rising Technology for Enhancing Transdermal Delivery of Drugs
Abstract: The skin has a total surface area of around 1.8 m2 and serves as the human body's interface with the outside world. The transdermal method of medication delivery has sparked a lot of interest in pharmaceutical research since it eliminates a lot of the issues that come with the oral route. Despite the fact that the skin, especially the stratum corneum, is a barrier to most medication absorption, it does …
Published in Trends in Drug Delivery · Vol. 8, Issue 3, 2023 · pp. 57–63 Read article
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Concise Review on Pharmacological Interventions in Diabetes: Impediment and Treatment
Abstract: Purpose about review: Diabetes is related with metabolic condition which is growing rapidly nowadays. The main reason behind the disease is autoimmune devastation of pancreatic beta cells that lead the impair action of the insulin on the tissues. Recent findings: Synthetic medications have various adverse drug reactions as well as treatment of cost is high. Consequently, herbal medicines have rising interest and gowning to replace the synthetic medications currently. Inference: …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 13, Issue 3, 2022 · pp. 14–20 Read article
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A Comprehensive Analysis of Aloe Vera Gel Processing and Its Antidiabetic Properties: A 3D Computational Biology Perspective"
Abstract: This expansive review paper delves into the intricate realm of Aloe vera gel processing and its potential antidiabetic properties, augmented through the lens of 3D computational biology. The review amalgamates insights from various references to elucidate the handling, harvesting, and juice extraction of Aloe vera gel. Additionally, it explores diverse products derived from Aloe vera, such as Aloe juice, Aloe health drink, and Aloe dessert, providing an extensive understanding of …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 10, Issue 2, 2023 · pp. 18–21 Read article