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2602 articles
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Advances in Solubility Enhancement Strategies for Poorly Water-soluble Drugs: A Comprehensive Review
Abstract: Solubility enhancement holds significant importance in the field of pharmaceutical research as it aims to augment the solubility and bioavailability of drugs that possess low solubility. Poorly soluble drugs pose a considerable challenge in drug development due to their tendency to display inadequate absorption, bioavailability, and therapeutic efficacy. The advancement of solubility enhancement techniques encompasses a wide range of approaches, including physical and chemical methods, as well as innovative technologies …
Published in International Journal of Vaccines · Vol. 1, Issue 1, 2024 · pp. 01–09 Read article
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Recombinant Insulin
Abstract: Recombinant insulin, a revolutionary product of biotechnology, has transformed the landscape of diabetes treatment. Developed through genetic engineering techniques, recombinant insulin offers a safer, more consistent alternative to traditional animal-derived insulin. Its production involves the insertion of the human insulin gene into host organisms such as Escherichia coli or Saccharomyces cerevisiae, which serve as efficient factories for insulin synthesis. Recombinant insulin is used to treat diabetic patients who are allergic …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 39–43 Read article
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Molecular Docking and Interaction of Anthocyanin Derivatives in Regulating Hippo-taz Pathway for Renal Injuries
Abstract: Introduction: The Hippo pathway plays a pivotal role in renal disease, with Yes-associated protein (YAP) exhibiting promise for combined treatments. The crucial evaluation of YAP-targeted drug safety and efficacy through preclinical studies is imperative. Additionally, α-SMA and SMAD3 emerge as potential therapeutic targets in renal fibrosis, driving ongoing research toward innovative interventions. Materials and Methods: In the systematic identification of therapeutic secondary metabolites, Anthocyanin derivatives were methodically retrieved from the …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 23–38 Read article
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Role of W.A.R. Score in Predicting Wound Infection
Abstract: In clinical practice, chronic wounds are a major difficulty that are frequently made worse by the infection risk. However, the lack of precise standards for evaluating the risk of infection and establishing the need for and length of time for systemic antibiotics leads to the overuse and abuse of these drugs, which increases the risk of side effects and the development of antibiotic resistance. To close this gap, the development …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 33–38 Read article
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Seasonal Variations of Air Quality Measures In Warri and Effurun, Delta State, Nigeria.
Abstract: Air quality in Urban Cities like Warri and Effurun has been deteriorating over time. The distribution levels of air pollutants in the Warri and Effurun environments may be related to both natural and man-made factors. In addition to evaluating the quality of rainwater with regard to pH, heavy metals (Fe, Pb, Cd, As, Hg, CU, Zn), and some anions (Cl-, NO3-, SO42-, CO32-), this project study aims to investigate, using …
Published in International Journal of Pollution: Prevention & Control · Vol. 2, Issue 1, 2024 · pp. 23–48 Read article
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Reusable Plastic Advantages, Challenges, and Impacts on Waste Management and Conservation Efforts
Abstract: The widespread utilization and ill-advised removal of single-use plastics have prompted critical natural contamination and asset consumption. Accordingly, society is progressively looking for supportable other options, with reusable plastic arising as a promising arrangement. This exploration paper intends to dig into the idea of reusable plastic, investigating its advantages, difficulties, and likely effect on squander the executives and preservation endeavors. Drawing on existing writing, contextual investigations, and mechanical progressions, the …
Published in International Journal of Pollution: Prevention & Control · Vol. 2, Issue 1, 2024 · pp. 14–22 Read article
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Millet Bran: Unveiling Its Potential Health Benefits
Abstract: Millet bran, derived from various millet grains, has emerged as a potent nutritional source, rich in fiber, vitamins, minerals, antioxidants, and omega-3 and omega-6 fatty acids. Its rising popularity is driven by its gluten-free nature, nutrient density, and sustainability. This review aims to explore the potential health benefits of millet bran, focusing on its digestive health, blood sugar control, heart health, antioxidant properties, and fatty acid composition. The Millet brand …
Published in International Journal of Nutritions · Vol. 1, Issue 2, 2024 · pp. 11–19 Read article
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Foxtail Millet (Setaria italica): A Detailed Review on Nutritional Value, Anti-Nutritive Value, Potential Health Benefits
Abstract: Millets are a diversified collection of small-seeded grasses that have been used as a primary source of grain for generations in various regions of Asia and Africa. Millets are a staple grain this is historically consumed in dry regions everywhere in the international. They are high in protein, fats, minerals, nutrients, and fiber.. Millets are highly nutritious grains rich in essential amino acids, minerals, and dietary fiber, offering health benefits …
Published in International Journal of Nutritions · Vol. 1, Issue 2, 2024 · pp. 20–26 Read article
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The Study of Nutritional Requirements and Physiological Changes in Space Station
Abstract: This article focuses on the impact of physiological adaptations to weightlessness on nutrient and food requirements in space. These modifications entail reductions in body water and plasma volume, which affect the cardiovascular and renal systems. Spaceflight poses intricate and predominantly detrimental effects on the human body, spanning both short and long durations. Long-term weightlessness leads to significant issues like muscle atrophy, skeletal deterioration, cardiovascular function deceleration, reduced red blood cell …
Published in International Journal of Nutritions · Vol. 1, Issue 2, 2024 · pp. 7–10 Read article
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A Trends in Dietary Supplement Related to Exercise Nutrition
Abstract: A product made to address physiological or nutritional demands that might occur during sports activity is called a dietary supplement. It could offer a convenient method for fulfilling specific nutritional needs during exercise, or it could be utilized to prevent or address common nutritional deficiencies experienced by athletes. It is crucial to include the supplement in a thorough plan for the best possible sports nutrition or clinical care of nutritional …
Published in International Journal of Nutritions · Vol. 1, Issue 2, 2024 · pp. 1–6 Read article
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Microwave Processing of Foods: Applications and Future Perspectives
Abstract: This paper introduces microwave-assisted processing of foods, fundamental principles and future perspectives provides a comprehensive exploration of the evolving landscape of microwave technology in the food processing. Despite widespread use in households, the industrial application of microwave processing remains relatively untapped. The narrative delves into specific applications, such as blanching, baking, pre-cooking, thawing and tempering, pasteurization, sterilization, microwave-assisted frying, rapid extraction, drying and inactivation of microorganisms, emphasizing the rapid temperature …
Published in International Journal of Nutritions · Vol. 1, Issue 2, 2024 · pp. 27–32 Read article
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IoT-Enabled Authentic Ration and Material Distribution Systems
Abstract: A home Ration Certificate is an essential item. The largest retailer system in India is Public Distribution System (PDS). A ration card is provided by the public distribution network, which is run by the state administration. All people have ration cards for purchasing essential consumers material like wheat, rice, kerosene, and oil. The present ration distribution system has many problems such as authentication problems, waste of time in queues, lots …
Published in International Journal of Solid State Innovations & Research · Vol. 1, Issue 1, 2023 · pp. 26–34 Read article
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Implementation and Impact of RFID in Library Management Systems
Abstract: This system relies on UHF RFID scanners at the gate and transaction section, which are supported by antennas and RFID transceivers embedded in library cards. These devices allow information to be electronically stored and read/written using radio waves without the need for physical interaction. It does not require manual input and instantly sends information about books and library users to the library's management system. It has a record-keeping and search …
Published in International Journal of Solid State Innovations & Research · Vol. 1, Issue 1, 2023 · pp. 20–25 Read article
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Green Human Resource Management: Trends in Sustainable and Agile Human Resources Research in SMEs
Abstract: Small and medium-sized enterprises (SMEs) collectively have a significant environmental impact, despite each individual SME having a relatively small footprint. To mitigate this impact, the implementation of green human resource management practices is crucial for effective workforce management within SMEs. However, SMEs face challenges in executing these strategies and ensuring long-term business continuity. This study aims to establish a theoretical framework for a business model that can assist SMEs in …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 1, Issue 2, 2023 · pp. 9–33 Read article
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Zolmitriptan Mouth Dissolving Tablets: Development of Formulas and Invitro Evaluation
Abstract: Pharma Burst ODT super disintegrants were used in different concentrations to manufacture Zolmitriptan fast dissolving tablets by a direct compression method. With a 28° angle of repose, there is good flow. The densities for bulk and tapped materials are 0.410 (g/ml) and 0.500 (g/ml), respectively. The compressibility index and Hausner ratio have values of 19.05 and 1.24, correspondingly. According to IP standard, weight variation test results range from 121.4 mg …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 2, 2024 · pp. 1–15 Read article
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Alopecia Areata: Complex Roots and Potential Cures
Abstract: Autoimmunity is when the healthy organs of an individual’s body are attacked by its own immune system, leading to illness or functional abnormalities. The hair follicles (HFs) are wrongly destroyed by the immune system in a condition known as Alopecia Areata and results in chronic non-cicatricial hair loss discernible by spherical patches. It’s a severely worsening or relapsing malady that can be permanent during severe falling out of hair. In …
Published in International Journal of Vaccines · Vol. 1, Issue 1, 2024 · pp. 41–54 Read article
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The Impact of Dietary Components on Lactation: A Critical Review
Abstract: Infant growth and well-being depend on an adequate and species-specific amount of nutrients, antibodies, and immunological components, which are provided by human breastfeeding, the cornerstone of newborn sustenance and development However, some moms struggle with producing inadequate milk, which can put the health advantages of nursing for both mother and child in jeopardy and cause stress, anxiety, and perhaps early weaning. This review discusses the fascinating idea that food changes …
Published in International Journal of Nutritions · Vol. 1, Issue 1, 2024 · pp. 31–36 Read article
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A study to assess the effect of nutritional supplementation on the hemoglobin level and the associated signs and symptoms of the students identified with anaemia in selected colleges of SNDT Womens’ University Mumbai
Abstract: The purpose of this study was to assess the effects of nutritional supplements on haemoglobin levels and related symptoms among students at SNDT Women's University in Mumbai who had been diagnosed with anaemia in a few particular institutions. Non-occurrence A sample of thirty anaemic students was selected via easy sampling. With a one-group pre-test-post-test methodology, the study used a descriptive evaluative design. Data collecting instruments included measurement devices, opinion questionnaires, …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 2, 2024 · pp. 16–25 Read article
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Engineering Perspectives: Thermal and Structural Examination of Disc Brakes for Light Vehicles
Abstract: The procedure of braking transforms the kinetic energy of a car into mechanical energy that needs to be released as heat. High temperatures may result from the frictional heat produced at the disc and pad interface during the braking phase. Frictional heat produced on the rotor surface can contribute to an excessive rise in temperature, which can have unfavorable effects including premature wear, brake fluid vaporization (BFV), thermally excited vibrations …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 1, Issue 2, 2023 · pp. 16–23 Read article
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Crafting Consumer Experiences: The Psychology of Retail Interior Design
Abstract: The psychology of retail interior design and its influence on consumer behaviour. Drawing upon theories from environmental psychology, consumer behaviour, and retail management, the study investigates how design elements such as colour, lighting, spatial layout, and sensory experiences shape consumer perceptions, emotions, and decision-making processes in retail environments. A comprehensive review of existing literature provides insights into established theories and previous research findings related to retail interior design and consumer …
Published in International Journal of Architectural Design and Planning · Vol. 2, Issue 1, 2024 · pp. 18–29 Read article