All articles
834 articles
-
Glitches in the Implementation of Bioinformatics in Medical Settings: A Comprehensive Review
Abstract: Bioinformatics is a dynamic field at the intersection of biology, computer science, and information technology, offering new possibilities in medicine by enabling a deeper understanding of genomics, molecular biology, and personalized treatment approaches. Its integration into healthcare could greatly enhance diagnostics, enable tailored treatments for individuals, and facilitate the analysis of large biological datasets. However, despite its potential, several barriers impede its successful implementation in clinical settings. These include technical …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 3, 2024 · pp. 1–6 Read article
-
Identifying Origin of Replication (ORI) sites in genomic sequence using Python-based programming and Motif analysis in Bioinformatics
Abstract: ORI sites serve a critical function in DNA replication serving as the beginning point of the process. Identifying the spots appropriately means a lot and is important for the biologists working in the lab. Detecting the ORI is not only vital for the detection of replication sites but is also important in numerous biological processes. In this study, we offer a unique approach employing Python-based motif analysis to discover the …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 3, 2024 · pp. 22–33 Read article
-
The Role of Bioinformatics in Nursing: Transforming Healthcare through Data-Driven Insights
Abstract: Bioinformatics, an interdisciplinary field combining biology, computer science, and information technology, is increasingly shaping the nursing profession. It offers powerful tools for improving patient care, advancing clinical research, and enabling personalized healthcare through data-driven decision-making. This article examines the integration of bioinformatics into nursing practice, tracing its historical roots from the Human Genome Project to its current applications in genomic medicine, precision healthcare, and population health. Nurses now play a …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 3, 2024 · pp. 18–21 Read article
-
Performance Analysis of Machine Learning Algorithms For Disease Prediction
Abstract: In this 21st century, where Digitization makes humans measure, record, analyze and to manipulate the huge amount of data as per the requirement, prediction of the decease based on Machine Learning models will be representing one of the good applications of the efficient data handling. An Automatic Decease Prediction system based on the symptoms would be the great boon for the medical practitioners. The Supervised Machine Learning models, such as …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 3, 2024 · pp. 9–18 Read article
-
Unlocking Wellness by Ayurveda with Contrasting Modern Medicine
Abstract: In the modern world, we are so subordinate to drugs that we are unable to imagine a single day without them. Like smartphones, we are also addicted to pharmaceuticals, which significantly impact our lives. Constant utilization of medicine makes resistance and dependence on the medicament. It moreover has diverse side effects that cause various health hazards. As people become aware of this, the utilization of herbal remedies has expanded worldwide. …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 3, 2024 · pp. 16–20 Read article
-
Infrared Radiation: A Non-Invasive Approach to Cholesterol Measurement
Abstract: Cholesterol levels and Diabetes have become prevalent worldwide. People who are physically disabled or unresponsive need to have their glucose and cholesterol levels constantly checked because it is hard to get accurate readings through invasive procedures or blood samples. Based on the proposed model, Hyperglycemia and Cholesterol amounts might be found without touching or taking blood specimens. The Arduino UNO and basic infrared sensors are used to make this happen. …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 3, 2024 · pp. 28–34 Read article
-
Don’t We Have Anything to Learn From the Past? Perspective of Epidemics
Abstract: History gives us the chance to learn from the past. In this article, a few of history’s biggest outbreaks, epidemics, and pandemics have been chronicled. The difference between these three are: an outbreak is when an illness occurs in an unexpectedly high number of individuals. It may stay in one area or extend more widely. An outbreak lasts up to several days to years. Sometimes, a single case of a …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 3, 2024 · pp. 21–27 Read article
-
Advanced Deep Learning Techniques for Sickle Cell Anaemia Detection
Abstract: Sickle Cell Anemia (SCA) is a prevalent genetic blood disorder characterized by the presence of abnormal hemoglobin, resulting in the distinctive sickle shape of red blood cells. Timely and accurate identification of Sickle Cell Anemia (SCA) is essential for effective management and treatment. This study presents a new method that utilizes Convolutional Neural Networks (CNNs), a deep learning model particularly effective for image analysis. The process involves using microscopic images …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 3, 2024 · pp. 9–15 Read article
-
A Community-Based Study to Assess: The Aggravating Factors and Treatment Choices in Youth with Acne
Abstract: Background and Aim: Acne vulgaris is a common dermatological condition affecting youth worldwide. While its pathogenesis is well-understood, individual experiences with aggravating factors and treatment choices vary. This study aimed to evaluate self-reported factors aggravating acne and determine treatment choices among youth with acne while assessing the correlation between self-perceived and clinically assessed acne severity. Methodology: A cross-sectional survey was conducted with 390 participants aged 18–24 suffering from acne. Data …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 3, 2024 · pp. 1–8 Read article
-
Dyslexia - A Correlational Study Between Brain and Hypothalamus That How They Are Affected in Dyslexic Child
Abstract: The 'dyslexia dispute' is tenacious. A crucial component of the media argument is the belief that dyslexia does not exist, which has been popularized by a number of outspoken commentators. For them, dyslexia are the creation of excessively anxious parents, backed up by a clique of private educational psychologists eager to deliver a diagnostic - for a charge - even when no condition exists. Critiques of dyslexia can also be …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 3, 2024 · pp. 28–36 Read article
-
Analysis of White Matter, Gray Matter, and Cerebrospinal Fluid Alterations in Neurological Disorders: A Deep Learning Approach
Abstract: This paper investigates the role of white matter (WM), gray matter (GM), and cerebrospinal fluid (CSF) alterations in the pathophysiology of neurological disorders, including Alzheimer’s disease, Parkinson’s disease, schizophrenia, and epilepsy. By leveraging advanced deep learning methodologies, we aim to automate the segmentation and analysis of brain structures from MRI scans, enabling a more detailed and precise evaluation of their roles in disease progression. These techniques allow for the identification …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 3, 2024 · pp. 21–27 Read article
-
Unravelling the Environment, Aroma, and Molecular Effects on Mood Fluctuations: A Review
Abstract: The ebb and flow of human emotions encompass a complex interplay of molecular processes governing mood fluctuations. This comprehensive review navigates the intricate realm of neurotransmitters, neuroplasticity, hormonal influences, genetics, and inflammation to unravel the molecular tapestry that shapes our emotional states. Foundational to mood regulation are neurotransmitters – serotonin, dopamine, and norepinephrine – orchestrating delicate balances within neural circuits. Recent molecular neuroscience elucidates their receptor pathways and signaling cascades, …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 3, 2024 · pp. 14–20 Read article
-
Exploring the Complexities of Parkinson’s Disease
Abstract: Parkinson’s disease (PD) is a neurological disorder, primarily affecting older adults, marked by both motor and non-motor symptoms. This review explores PD as a multisystem disorder that influences the central, enteric, and autonomic nervous systems, along with the immune system and gastrointestinal tract. Key pathogenic features include the degeneration of dopamine-producing neurons in the substantia nigra and the formation of Lewy bodies containing misfolded α-synuclein proteins. The bradykinesia, tremors, stiffness, …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 3, 2024 · pp. 1–8 Read article
-
Complex Tuberculous Meningitis: A Case Series Highlighting Rare Co-infections and Severe Complications
Abstract: This case series presents two complex cases of tuberculous meningitis (TBM) with different complications, illustrating the diverse clinical presentations and management challenges of this disease. Case 1 involves an 18-year-old female with TBM complicated by cryptococcal co-infection, while Case 2 describes a 64-year-old female with TBM complicated by obstructive hydrocephalus and secondary bacterial infections. Both patients had been on anti-tubercular therapy before presentation. Diagnostic approaches included cerebrospinal fluid analysis, cultures, …
Published in International Journal of Pathogens · Vol. 1, Issue 2, 2024 · pp. 1–7 Read article
-
SiRNA-Based Multivalent Vaccines: A Systematic Review of Potential Risks, Benefits, and Future Applications
Abstract: Background: Small interfering RNA (SiRNA) technology represents a promising innovation in vaccine development, especially for multivalent vaccines that can target multiple pathogens or antigenic variants simultaneously. siRNA-based vaccines offer a unique mechanism to induce specific immune responses, presenting an adaptable and potentially powerful tool for tackling infectious diseases and cancer. Methods: This systematic review synthesizes recent studies on siRNA multivalent vaccines, focusing on their immunogenicity, safety, and effectiveness. We reviewed …
Published in International Journal of Vaccines · Vol. 2, Issue 1, 2025 · pp. 43–49 Read article
-
Influence of Acidic Naf-Hf Solution on Dental Minerals
Abstract: The effect of solutions of sodium fluoride in hydrofluoric acid on the fluoride-dental minerals reaction system was investigated. The fluoride concentration in each fluoride solution was kept at 1.23% as the fluoride concentration in the acidulated phosphate fluoride solution at pH 3. The acidic sodium fluoride-hydrofluoric acid solutions with different contents of sodium fluoride and hydrofluoric acid were prepared. These solutions were added to synthetic powder hydroxyapatite and calcium hydrogen …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 3, 2024 · pp. 27–37 Read article
-
The Power of Genetic Engineering in Revolutionizing Vaccines
Abstract: Genetic engineering techniques, including recombinant subunit, viral vector, and nucleic acid vaccines have transformed the landscape of vaccine development. These novel approaches offer precise antigen design, enhanced safety profiles, and rapid adaptability to emerging pathogens. Key advantages include improved efficacy through targeted immune responses, increased safety due to the absence of live pathogens, and the ability to modify vaccines to address new variants or diseases quickly. Notable success stories, such …
Published in International Journal of Vaccines · Vol. 2, Issue 1, 2025 · pp. 18–27 Read article
-
Effect of 940-nm Low-Level Laser Therapy on Tooth Movement Rate during Orthodontic Treatment: A Split-Mouth Double-Blind Randomized-Controlled Trial
Abstract: This study aimed to evaluate the effect of low-level laser with wavelength of 940 nm on acceleration of orthodontic tooth movement. Materials and Methods: This study was a double-blind randomized-controlled trial with split-mouth design. Fifty-five patients whose four first premolars were extracted for orthodontic treatment were randomly allocated to group A (n = 27) and group B (n = 28). Canine retraction was performed using the force of 150 g …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 3, 2024 · pp. 14–20 Read article
-
DentiDetect: Dental Diagnosis Powered by Deep Learning
Abstract: Dental X-rays play a crucial role in modern dentistry, enabling dentists to detect cavities, bone loss, and other hidden dental issues that are not easily visible during a routine examination. X-rays offer a clear picture of teeth, bones, and nearby tissues, enabling early identification of issues. This helps create more efficient treatment strategies and improves patient outcomes. Three commonly used types of X-rays include bitewing, periapical, and panoramic. Bitewing X-rays …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 3, 2024 · pp. 21–26 Read article
-
Understanding Trichotillomania: Exploring and Managing Hair-Pulling Disorder
Abstract: One form of traumatic alopecia is called trichotillomania, which is characterized by an overwhelming impulse to take out hair and a feeling of comfort once the hair has been removed. Alopecia in trichotillomania results from the patient’s deliberate act of pulling out their own hair, often triggered by feelings of stress, tension, or psychological distress. This condition, classified as a mental health disorder, leads to noticeable hair loss that can …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 3, 2024 Read article