Efficacy of Apium graveolens (Bekh Karafs) in Hyperuricemia: A Randomized Single Blind Standard Control Study

M. A. Siddiqui; Nasimul H.; arshid IQBAL wani

doi:10.37591/rrjom.v7i2.53

Abstract

Hyperuricemia may induce certain complications like gouty arthritis, nephrolithiasis and uricacid nephropathy. Owing to its dreadful complications, the researchers of different system ofmedicine are concentrating themselves for the development of new drugs, which can loweruric acid level in blood. The main aim of the study was to assess the efficacy of Apiumgraveolens in lowering the serum uric acid level in blood. The present study was a singleblind, randomized standard control study carried out at the department of Medicine(Moalajat) in National Institute of Unani Medicine Bengaluru. A total of 40 patients ofhyperuricemia of either gender, above 20 years and below 70 years of age were selected andrandomly assigned to control and test group; comprising 20 patients in each group. Testgroup was treated with Apium graveolens 10 gm once a day in the form of decoction, whereascontrol group was given Allopurinol, 1 tablet each 100 mg three times a day for 45 days. Allthe patients were assessed on subjective and objective parameters. The result was analyzedstatistically using Wilcoxan signed rank test and Chi square test, RM ANOVA, and Student ttest. At the end of the study, significant reductions in joint pain and serum uric acid levelswere observed in test as well as in control group when compared to baseline. However, nostatistically significant differences were observed between test and control groups. The overalleffect of the Apium graveolens was found quite encouraging in the treatment ofhyperuricemia.Keywords: Hyperuricemia, Apium graveolens, Bekh karafs, goutCite this ArticleM.A Siddiqui, Nasimul H., Arshid IqbalWani. Efficacy of Apium graveolens(Bekh Karafs) in Hyperuricemia: ARandomized Single Blind StandardControl Study. Research & Reviews:Journal of Medicine. 2017; 7(2): 7–12p.