Volume 3, Issue 1 (2016)
Published
Table of contents
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Microemulsion: Novel Carrier for Drug Delivery
Abstract: Since the discovery of much novel formulation belongs to the lipid based drug delivery system, the handicapped property of drug molecule reverted to the fittest, doable and easily delivered with strategies of improving bioavailability and depleting dose of the same. Microemulsion system is clear, stable, isotropic mixture of oil, water and Smix (Surfactant and co-surfactant mixture), frequently in combination with a co-solvents. To date microemulsions have been shown to be …
Published in Trends in Drug Delivery · Vol. 3, Issue 1, 2016 · pp. 1–18 Read article
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Antibiotics Utilization Pattern in Pediatric Ward of Ghimbi Adventist Hospital, Ghimbi Town, Oromia Region, West Ethiopia
Abstract: Drug use evaluation is ongoing systematic process designed to maintain the appropriate and effective use of drugs. It is used to ensure that drugs are used appropriately, safely and effectively to improve patients’ health status. The general objective of the study was to assess antibiotics utilization patterns in pediatric ward of Ghimbi Adventist Hospital (GAH), Ghimbi town, Oromia region, West Ethiopia.A hospital-based retrospective cross-sectional study was conducted to assess the …
Published in Trends in Drug Delivery · Vol. 3, Issue 1, 2016 · pp. 19–30 Read article
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European Regulatory Perspective on Super-Generics: Antacid Orally Disintegrating Tablets (ODT)
Abstract: Super-generic is the general form of nomenclature for hybrid medicinal product in European Union (EU). The super-generic form of the medicinal product is one that considers changes in the form of active substance, therapeutic indications, strength, pharmaceutical form or route of administration. They rely partly on results of preclinical tests and clinical trials of an innovator product and also on new data with appropriate bioavailability and bioequivalence studies. Marketing authorization …
Published in Trends in Drug Delivery · Vol. 3, Issue 1, 2016 · pp. 31–37 Read article
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Recent Advances and Technologies in Transdermal Drug Delivery System
Abstract: Transdermal drug delivery system is usually well liked by patients and second in terms of preference after oral route. The global market for transdermal system is expected to rise in near future. Skin is considered to be the major barrier in transdermal delivery. However, few technologies and advances such as radiofrequency, ultrasound, electroporation, iontophoresis, and microneedle have been identified to overcome these barriers. Systems or devices that incorporate these technologies …
Published in Trends in Drug Delivery · Vol. 3, Issue 1, 2016 · pp. 38–45 Read article
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UV Spectrophotometric Method for the Estimation of Etoposide and its Application in Study of Polymeric Nanoparticles
Abstract: A rapid, economical, accurate and simple UV spectrophotometric method was developed for quantification of etoposide in bulk and pharmaceutical formulation and its application in the study of polymeric nanoparticles. The samples were quantified at 284 nm in both methanol and phosphate buffer saline (PBS) at pH 7.4. The method was linear (r2 > 0.99) over the range of 20–100 μg/ml, precise (RSD < 5%), accurate (recovery values close to 100%), …
Published in Trends in Drug Delivery · Vol. 3, Issue 1, 2016 · pp. 46–51 Read article