Research and Reviews: A Journal of Pharmaceutical Science
Volume 5, Issue 1 (2014)
Published
Table of contents
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Compulsory Licensing – The Effect on Generics, Patents and Drug-Development in Indian Pharma
Abstract: The objective of the present study was to analyse the effect of compulsory licensing (CL) on Generics, Patents and Drug-Development in India. This analytical study was carried out by collection of the data with respect to research questions. The data were collected from WTO, research articles, journals, ICMR and DCGI guidelines, Drugs and Cosmetics Act, WHO guidelines, TRIPS agreement, Indian Patents Act. The results revealed that expiry of three years …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 5, Issue 1, 2014 · pp. 1–13 Read article
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Enhanced Iron Removal in Experimental Iron Overload by Nanoniosomes of Desferrioxamine
Abstract: This preliminary study explores the feasibility of employing nanocapsules prepared from nonionic surfactant vesicles (niosomes) as a carrier for an iron-chelating agent, Desferrioxamine (DFO, Desferal), to enhance iron excretion from the body. The methodology consisted of creating an iron overload model in an experimental animal followed by measurement of iron excretion pattern in the urine by atomic absorption spectrophotometry. Niosomes were prepared with span 60: cholesterol:dicetyl phosphate by the lipid …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 5, Issue 1, 2014 · pp. 14–20 Read article
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Nanoinformatics: An Overview
Abstract: Nanoinformatics uses informatics techniques to (i) collect, (ii) process, (iii) store, and (iv) retrieve information on nanoparticles/nanomaterials/nanodevices and their potential applications in health care. Nanoinformatics assists to develop new computing applications to accelerate research and development in nanomedicine. In this context, it is playing an important role in acquiring relevant data and information, conceptually organizing information for conversion to knowledge, and developing computing applications that are based on important parameters …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 5, Issue 1, 2014 · pp. 21–25 Read article
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Patterns of Antihypertensive Drug Utilization in a West Indies University Teaching Hospital
Abstract: Objective of this study was to determine the prescribing patterns of antihypertensive medications in specialty outpatient clinics in a tertiary care hospital of a Caribbean developing country. A retrospective prescription-based survey was conducted in the renal and cardiac outpatient clinics during the period September to December 2006. Data recorded included demographic data, antihypertensive and other drugs prescribed, duration of prescription, adverse drug reactions and side effects. A total of 285 …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 5, Issue 1, 2014 · pp. 26–34 Read article