Research and Reviews: Journal of Oncology and Hematology
Volume 9, Issue 3 (2020)
Published
Table of contents
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A Literature Review on Future Perspective of Metformin use for Chemotherapy
Abstract: The emergence of metformin as a potential anticancer and cancer-preventive therapeutic tool is exciting. More recently, metformin has been associated with decreased cancer incidence and mortality in diabetic patients and the insulin-lowering effects of metformin are integral to its anticancer properties. With the added benefits of being readily available, economical, and easily tolerated with good safety profile, it can be effortlessly transitioned from bench to bedside for cancer therapy. So, …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 3, 2020 · pp. 1–9 Read article
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To Develop Self-instructional Module on ‘Umbilical Cord Stem Cell Collection, Preservation and Utilization’ and Evaluate its Effectiveness on Improving the Knowledge of Operational Level Nurses
Abstract: Umbilical cord stem cell based regenerative and cellular medicine has now become a fascination for all. The umbilical cord blood, donated by mothers after the birth of newborn, has become an accepted source of hematopoietic stem cells for bone marrow reconstitution. They play an important role in the treatment of blood and immune system related genetic diseases, cancers, and blood disorders. This study is aimed to assess the knowledge of …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 3, 2020 · pp. 10–22 Read article
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Human Arginase I (Arg I)—A Potential Broad-spectrum Anti-cancer Agent: Perspectives and the Road Ahead
Abstract: Cancer is the second leading cause of morbidity and mortality globally. A variety of effective regimens are available for the treatment of different cancers, however, there is still a need for the development of safe and effective broad-spectrum anti-cancer agent(s). Towards this, amino acid-depleting enzymes have proven to be effective in the treatment of certain auxotrophic cancers. In this review, we have briefly discussed arginine metabolism and arginine depletion as …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 3, 2020 · pp. 23–35 Read article
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Nitrosamine: The Carcinogenic Impurity in Angiotensin Receptor Blockers
Abstract: Angiotensin II Receptor Blockers (ARBs), commonly known as the Sartans, are used in the treatment of hypertension for a long time. Currently, seven Sartan drugs, i.e. Valsartan, Losartan, Candesartan, Irbesartan, Telmisartan, Olmesartan, and Eprosartan, are in use. Recently, Nitroso impurity was detected in Valsartan active pharmaceutical ingredient, which led to the recall of batches of products containing it. Even in trace amounts, the impurity is said to be a probable …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 3, 2020 · pp. 36–43 Read article
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The Effect of the 632.8 nm Laser Blood Irradiation on PASI, TC and TG in Patients with Psoriasis Vulgaris
Abstract: Objectives: The aim of this study is to study the effect of the 632.8nm laser blood irradiation (LBI) on PASI, TC and TG in patients with psoriasis vulgaris. Patients and methods: A total of 90 cases of psoriasis vulgaris were divided into 3 groups according to the paths of laser irradiation: Intravenous Laser Blood Irradiation (ILBI: A Group), nasal mucous irradiation (B Group), no irradiation (C Group). All patients were …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 3, 2020 · pp. 44–46 Read article