Research and Reviews: Journal of Oncology and Hematology
Volume 1, Issue 2 (2012)
Published
Table of contents
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Emerging Engineered Nanoweapons for Tumors
Abstract: Cancer is a type of disease characterized by abnormal growth of cells which tend to proliferate in uncontrolled manner. It occurs at molecular level when genes undergo genetic alterations. The malignant growth of tumor cells results in non-functioning of the concerned organ. Over the years, cancer targeting technique has greatly improved by new approaches based on nanotechnology. Nanotechnology is helpful in development of new therapies against cancer. Nanotechnology is a …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 1, Issue 2, 2012 · pp. 1–6 Read article
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Malignancies during Pregnancy – A Case Series and a Brief Review of Literature
Abstract: Although occurrence of malignancy in pregnancy is rare, it accounts for a third of all maternal deaths during gestation. The advances in reproductive medicine and deliberate postponement of pregnancy till a later age may show a rise in the incidence of malignancies in pregnancy in future. Lack of standard guidelines is a major hurdle in the management of cancer in pregnancy. Our aim was to do a retrospective analysis of …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 1, Issue 2, 2012 · pp. 13–20 Read article
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Inhibition of MDA-MB-231 Breast Cancer Cell Proliferation by Simple Diphenyl Chalcone and Its Chlorinated Derivatives
Abstract: The pharmacological activities of chalcones and their derivatives are well documented. Chalcones are an important class of natural products that occur in edible plants such as spices, tea, fruits and other vegetables. In vitro studies have shown that chalcones inhibit proliferation of breast cancer cells by inducing apoptosis and blocking cell cycle progression. Substituent effects, namely, adding electron-withdrawing substituents to the chalcone structural motif, and the extents to which those …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 1, Issue 2, 2012 · pp. 7–12 Read article