Research and Reviews : A Journal of Medical Science and Technology
Volume 12, Issue 3 (2024)
Published
Table of contents
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Hemophilia and Gene Therapy–Review
Abstract: The coagulation factor VIII or factor IX genes are affected by the monogenic mutational illness known as hemophilia. Recombinant clotting factors, which are secure and efficient, are the preferred palliative therapy. In order to ensure steady and long-lasting concentrations of the damaged circulating factor, advanced therapies will be curative. Adeno-associated vectors have primarily been used, and the results have been positive in terms of amounts and timings of expression. These …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 3, 2024 · pp. 1–5 Read article
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Comparison of the Effects of Voriconazole and its Nanogel form on Aspergillus Flavus Isolates in Vitro
Abstract: Aspergillus species are one of the most critical environmental fungi and are considered as a severe factor in causing hospital infections of foreign origin. Objective: Aspergillus flavus is a saprophytic and pathogenic fungus and is found all over the world. In clinical isolates, the voriconazole drug effectively affects more than 95% of Aspergillus isolates. These common drugs have limitations for maximum effect in patients, so nanomedicines are designed and manufactured …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 3, 2024 · pp. 14–20 Read article
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Lower Extremity Dysfunction in Recreational Footballers: A Cross-sectional Study
Abstract: The purpose of the present study was to evaluate the lower extremity dysfunction in male recreational football players. A cross-sectional survey was carried out on 100 recreational football male players using lower extremity functional scale questionnaire including males and females in the age group 17– 25 years. Football players are most frequently impacted by 37% of them having trouble making abrupt turns while sprinting, 26% having trouble running on uneven …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 3, 2024 · pp. 21–26 Read article
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A Review Drug and Biochemical Pharmacology Discovery
Abstract: The development of new therapeutic approaches and our understanding of disease mechanisms have both benefited ground-breaking medications as they are advanced and show the value of contemporary technologies, methodologies, and genetics in drug discovery. The synthesis, design, and application of these molecules have become a focal point in drug discovery efforts. The present research paper provided a comprehensive study of the recent developments in the field of biochemical pharmacology and …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 3, 2024 · pp. 27–31 Read article
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Child-oriented Care: Current Applications and Future: A Critical Review
Abstract: Child-oriented care is an evolving paradigm in paediatric healthcare, emphasizing the well-being and unique needs of paediatric patients and their families. This critical review explores the current applications of child-oriented care, including child-friendly hospital environments, the vital role of child life specialists, family-centred rounds, paediatric pain management, child-centred communication, and the integration of child life apps and virtual support systems. These strategies collectively foster a more compassionate, engaging, and effective …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 3, 2024 · pp. 32–37 Read article
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An experimental study to assess the efficacy of VAT on knowledge of Breast Cancer and practice of BSE among women in Chittoor, Andhra Pradesh
Abstract: Introduction: Breast cancer is more common in developing and industrialized nations alike, including India. Every year, more than a million cases of breast cancer are diagnosed worldwide. Insufficient awareness on breast cancer has been shown to be a significant contributing cause to the high rates of morbidity and death among women by refraining them from going to screening facilities, participating in BSE, and delaying treatment. Breast Cancers are second most …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 3, 2024 · pp. 38–42 Read article
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A Medicolegal study on structural characteristics of hyoid bone and mandible associated with sex and age
Abstract: Background: In recent studies, some data is presented that the estimation of gender and age could be possible using morphological characteristics of hyoid and mandible in dead bodies. For example, the mandibular angle is greater with growing age and female has narrower basihyal bone than male. However, it hasn’t yet studied about the exact digital materials. In this research, gender and age were estimated according to the morphological characteristics of …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 3, 2024 · pp. 43–51 Read article
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Design of Modelling Tool for Electronic Clinical Pathway based on Workflow and Standardised Terminologies
Abstract: It is very important to transform paper-based clinical pathways (CPs) into computer-readable format in order to integrate CPs into hospital information system (HIS). Modelling approaches of CPs include workflow management techniques, ontology and Petri net. Workflow-based modelling has a potential for representing sequenced medical activities in CPs, however previous approaches showed inadequate representation of medical content of CPs. Petri net and ontology-based modelling approaches have been widely used in modelling …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 3, 2024 · pp. 52–63 Read article
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Knowledge and Attitude Towards COVID-19 Vaccination Among Urban Population
Abstract: COVID-19, short for Coronavirus Disease 2019, is a rapidly spreading global pandemic caused by a novel human coronavirus initially named 2019-nCov and now known as SARS-CoV-2. This outbreak was first identified in December 2019 when patients in Wuhan, China, displayed symptoms of viral pneumonia. Our understanding of COVID-19 vaccines is currently limited, and it is expected that people's perspectives and attitudes toward these vaccines will vary widely among and within …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 3, 2024 · pp. 6–13 Read article
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Integration of Blockchain Technology in Healthcare: Opportunities and Challenges
Abstract: Blockchain is transforming data management with decentralization, immutability, and transparency, particularly in healthcare. It addresses challenges like data protection, interoperability, and supply chain traceability. Blockchain's evolution highlights rapid growth and dynamic research interests, empowering healthcare stakeholders with patient-centric approaches. Immutability ensures data accuracy and security, fostering trust. Its profound impact on clinical research, patient engagement, and self-management is evident. Challenges in scalability, interoperability, and regulatory frameworks persist. Real-world applications showcase …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 3, 2024 · pp. 64–77 Read article