Research & Reviews: A Journal of Drug Design & Discovery
Volume 7, Issue 2 (2020)
Published
Table of contents
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A Brief Review on Novel (COVID-19) Corona Virus and Its Management – The Global Pandemic Situation
Abstract: AbstractCOVID -19 is a respiratory disease that is contagious, first detected in china and worldwide spread in December 2019. The novel (new) coronavirus (nCoV) coronavirus disease 2019, or COVID-19 that cause illness ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS-CoV) and Severe Acute Respiratory Syndrome(SARS-CoV). A novel coronavirus is a new strain that has not been previously identified in humans. Genus Coronaviruses …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 7, Issue 2, 2020 · pp. 1–7 Read article
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An Insight to Epidemiology, Diagnosis and Treatment of COVID-19
Abstract: Abstract Since late December, 2019 an outbreak of a novel coronavirus disease was reported in Wuhan, China with severe acute respiratory syndrome (SARS). It is commonly known as COVID-19 means a disease caused by coronavirus and the first case was identified in 2019. The WHO declared the COVID-19 a global pandemic in March, 2020 because it affected more than 100 countries worldwide. In this review we summarize epidemiology, diagnosis and …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 7, Issue 2, 2020 · pp. 13–22 Read article
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Perioperative stress relief: a new role for the love hormone???
Abstract: AbstractThe hormone oxytocin(OXT) was originally known to stimulate labour and maternal milk ejection. It is also known to produce anti-stress like effects, anxiolytic effects, improvement in social interaction, reduction in blood pressure and cortisol levels and promotion of growth and healing. It is in fact popularly called as the ‘love hormone’, or the ‘hug hormone’ or the ‘cuddle hormone’. It is administered commonly intravenously in labor rooms and maternity suites …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 7, Issue 2, 2020 · pp. 23–27 Read article
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Phytoconstituents of Eclipta alba Targeting Various Protein Sequences of Coronavirus: An Insilco Approach
Abstract: Abstract Background: The major disaster in the 21st century is the Novel-Coronavirus 2019 (nCoV or COVID-19) and Severe Acute Respiratory Syndrome-related coronavirus (SARS-CoV). In the year 2019, a new strain of coronavirus (CoV) was recognized in Wuhan city of China. In the current scenario there is no specific drug or therapy is for treating COVID-19 infections which is turning to be extremely fatal. Based on the literature survey for natural …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 7, Issue 2, 2020 · pp. 28–51 Read article
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An Approach to Treat Corvid-19: An Opinion to Use Angiotensin Converting and 4-Dipeptidyl Peptidase Enzymes Inhibitors
Abstract: Abstract Coronavirus (CoV) attach the cell surface and enter the host cell via interaction with angiotensin converting enzyme receptor. Viral replication induces dysregulation of the autophagy process and interferes with the natural function of the lysosomes. Antimalarial drugs, including chloroquine and hydroxychloroquine through their lysosomotropic and autophagy inhibiting effects may be useful in the management of CoV infections. Among the people who at risk of developing CoV infections are hypertensive …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 7, Issue 2, 2020 · pp. 8–12 Read article