Research & Reviews: A Journal of Drug Design & Discovery
Volume 1, Issue 2 (2014)
Published
Table of contents
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Antibacterial Activity and Preliminary Phytochemical Screening of the Extracts of the Bark of Moringa oleifera
Abstract: Ethyl acetate, acetone, methanol and aqueous extracts of the bark Moringa oleifera were screened against the enteric pathogens isolates namely, Esherichia coli, Shigella sonnei and Salmonella enteritis. All the extracts other than aqueous extract showed antimicrobial activity with the methanol extract having the percentage of activity. Preliminary phytochemical screening revealed the presence of and tannins in the methanol extract. Keywords: Moringa oleifera, bark, antimicrobial activity, flavones, tannins
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 1, Issue 2, 2014 · pp. 1–4 Read article
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Pharmacology of Herbal Drugs: Ayurvedic Approach
Abstract: Herbal drugs are gaining acceptance globally. The present approach of studying them is based on modern parameters. Most of these drugs are described in ancient Ayurvedic treatises and so Ayurvedic method of studying pharmacology is necessary. It is also necessary to study pharmacokinetics as per Ayurveda only. The study of the herbs is to be done in following steps. The first step is to study fivefold properties of herb, i.e., …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 1, Issue 2, 2014 · pp. 12–14 Read article
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A Comprehensive Literary Review on Heavenly Elixir–Amrita
Abstract: Tinospora cordifolia (Willd.) Hook. f. and Thoms. (Amrita) is the most researched drug since ancient time till contemporary era regarding its wide range of therapeutics. One can witness several research papers published in indexed journal pioneering role of Amrita in human health care. This review article is an attempt to concentrate purely on the classical contour and focusing on literary findings regarding the Amrita. Keywords: Ayurveda, amrita, tinospora cordifolia, literary …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 1, Issue 2, 2014 · pp. 15–22 Read article
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Antibacterial Activity of Leaf and Flower Extract of Lablab purpureus against Clinical Isolates of Staphylococcus aureus
Abstract: The present study was undertaken to determine inhibitory activity of leaf and flower extracts of Lablab purpureus against clinical isolates of Staphylococcus aureus. Agar well diffusion assay was performed to determine antibacterial activity. Among extracts, the flower extract has shown marked inhibition of S. aureus isolates. It can be concluded that the leaf and flower extracts possess inhibitory components. The bioactive components present in the plant are to be separated …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 1, Issue 2, 2014 · pp. 5–7 Read article
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Single Nucleotide Polymorphism in CYP17 and CYP19 in Breast Cancer
Abstract: A single T > C change at the 5’ promoter region of the CYP17 and CYP19 genes are reported to be associated with increased risk of breast cancer. This study evaluates the influence of genetic polymorphism of CYP17 and CYP19 on breast cancer susceptibility. Ten patients with histopathologically confirmed breast cancer and 30 age-matched controls were included in study. A polymerase chain reaction – single nucleotide polymorphism (PCR-SSCP) method was …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 1, Issue 2, 2014 · pp. 8–11 Read article