Research and Reviews : Journal of Computational Biology
Volume 14, Issue 3 (2025)
Table of contents
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AI Approaches in Gait and Posture Analysis: A Review
Abstract: This review synthesizes current research on the application of artificial intelligence (AI) in gait and posture analysis, focusing on methodologies, algorithms, and clinical applications. It examines the use of machine learning (ML) and deep learning (DL) techniques to extract relevant features from sensorderived data, offering objective, and automated assessments that surpass traditional methods. A systematic literature review was conducted, analyzing studies that utilized AI for gait and posture analysis with …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 3, 2025 · pp. 1–3 Read article
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A Comprehensive Review of CNN-Based Framework for Multi-Sign Detection of Diabetic Retinopathy in Fundus Images Using Public Datasets
Abstract: Diabetic retinopathy (DR) is one of the main causes of vision impairment. Blindness prevention and effective treatment depend on early detection. A thorough deep learning-based framework for the automatic segmentation and simultaneous detection of exudates, hemorrhages, and microaneurysms – three important DR indicators – from retinal fundus images is presented in this work. These three pathological signs’ corresponding annotated image patches, along with background (no-sign) areas, were used to train …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 3, 2025 · pp. 14–23 Read article
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Artificial intelligence’s role in mental health: Innovations, Challenges, and future prospects
Abstract: Among the many ways in which mental health services are gaining from the integration of artificial intelligence (AI) are improvements in diagnosis, tailored treatment programs, and round the- clock patient help. Two AI-driven solutions are virtual therapists and prediction algorithms, which could increase access to mental health therapy and enable early intervention. However, the application of artificial intelligence in this field raises ethical concerns about privacy, discrimination, and the potential …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 3, 2025 · pp. 14–23 Read article
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Role of Artificial Intelligence in Health Care Decision Making: Balancing Innovation and Caution
Abstract: Healthcare is undergoing a transformation powered by artificial intelligence, which improves monitoring, diagnosis, and treatment capabilities. Among Artificial Intelligence (AI's) shortcomings is the dearth of an emotional relationship between individuals and medical personnel. Robotic surgery procedures pose the possibility of malfunctioning machinery and mistaken assumptions. So, the present systematic review focused on exploring the boon and bane of the role of AI in predicting various abnormalities in advance to improve …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 3, 2025 · pp. 24–35 Read article
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Integrative Network Biology Analysis of GSE6011 Uncovers Molecular Signatures in Duchenne Muscular Dystrophy
Abstract: Duchenne muscular dystrophy (DMD) is a rare, severe neuromuscular disorder demonstrated by progressive skeletal muscle deterioration and premature mortality. Despite advances in supportive care, no definitive cure exists, highlighting the need to explore novel molecular targets. The current study aimed to uncover key dysregulated genes and molecular pathways in DMD through a dataset-specific network biology approach. Publicly available microarray data (GSE6011) from DMD quadriceps muscle biopsies of 22 patients and …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 3, 2025 · pp. 36–48 Read article