Research and Reviews : Journal of Computational Biology
Volume 10, Issue 3 (2021)
Published
Table of contents
-
Computational Biology & Bioinformatics: A Gentle Overview
Abstract: Computational biology organises our understanding of life, makes biological concepts rigorous and testable, and provides a reference map that connects individual insights. The next modern synthesis in biology will be driven by the incorporation of mathematical, statistical, and computational methods into mainstream biological education, transforming biology into a quantitative science. Bioinformatics is divided into several branches, including Genomics, Proteomics, Computer-Aided Drug Design, Bio Data Bases & Data Mining, Molecular Phylogenetics, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 10, Issue 3, 2021 · pp. 1–3 Read article
-
The Basics of Genomics, Proteogenomics: The Demands and Roles that Proteomics can Fulfil in Genome Annotation
Abstract: The science of genomes: scientists have only recently gone from analysing a few or a limited number of genes at a time to investigating thousands of genes, moving from the study of inheritance units to the investigation of an organism's entire genome. The science of genomes, or "genomics," was originally focused to determining DNA sequences (the nucleotide order on a specific fragment of DNA), but it quickly evolved to a …
Published in Research and Reviews : Journal of Computational Biology · Vol. 10, Issue 3, 2021 · pp. 10–12 Read article
-
To Find the Nucleotide and Protein Sequence of AMYLASE in Homo Sapiens in FASTA Format
Abstract: Comprehensive analysis of current enzymes with α-amylase activity (AAMY) belonging to family 13 of glycoside hydrolases (arrangements of 144 archaea, bacteria, and eukaryotes from different species of GH13; 87). Offers. This study aims to deepen our knowledge of the evolutionary molecular relationships between the sequences of the A and B domains, with a particular focus on the correlation between what is observed in structure and the evolution of proteins. A-domain …
Published in Research and Reviews : Journal of Computational Biology · Vol. 10, Issue 3, 2021 · pp. 13–15 Read article
-
To Explore and Download the Genome Sequence of Drosophila Melanogaster at NCBI
Abstract: Drosophila melanogaster is one of the most intensively studied organisms in biology, serving as a model system for many developmental and cellular processes shared by higher eukaryotes, including humans. A shotgun whole-genome sequencing strategy was used to sequence almost the entire nucleotide of the approximately 120-megamegabase euchromatic portion of the Drosophila genome. It is supported by extensive clone-based sequences and high quality bacterial artificial chromosome maps. Work is being done …
Published in Research and Reviews : Journal of Computational Biology · Vol. 10, Issue 3, 2021 · pp. 4–6 Read article
-
An Introduction to Proteome Bioinformatics
Abstract: For basic and translational research, high-throughput approaches are essential. Recent improvements in proteomics techniques, for example, have allowed biomedical researchers to characterise the proteome of a variety of creatures. Proteome bioinformatics approaches and technologies have greatly aided this extraordinary progress. The study and use of informatics in the realm of proteomics is known as proteome bioinformatics. This chapter presents an overview of the computational strategies, methodologies, and techniques for bioinformatics …
Published in Research and Reviews : Journal of Computational Biology · Vol. 10, Issue 3, 2021 · pp. 7–9 Read article