Research & Reviews: A Journal of Bioinformatics
Volume 6, Issue 2 (2019)
Published
Table of contents
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Speech Perception in Geriatric Population
Abstract: Ageing is one of the characteristic features seen in organisms of the animal kingdom; after birth via ageing first the development and maturation take place which when progresses with time results in degeneration and ultimately ends with the end of the life cycle of the organism. As humans are no different; our maturation phase starts right after birth, which results in complete maturation by the time humans reach adulthood [1]. …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 6, Issue 2, 2019 · pp. 1–3 Read article
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In silico Screening of Some Natural Sesquiterpenes Against Diverse Therapeutic Targets: A Multitargeted Approach
Abstract: The present research was rational in-silico based exploration of other significantly essential pharmacological potentials of the existing natural sesquiterpenes by using the Schrodinger software which is already known to scientific community owing to their anticancer and antibacterial potentials. The sesquiterpenes have been explored for possible therapeutic excellence by screening against Lipoxygenase-5 (anti-inflammatory), Cycloxygenase-2 (anti-inflammatory), Dipeptidyl peptidase (antidiabetic), Cyclin-Dependent Kinase-5 (anticancer), Angiotensin-1 Converting Enzyme (antihypertensive), and Protein kinase C (anticancer). The …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 6, Issue 2, 2019 · pp. 10–15 Read article
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Auditory Tone Monitoring in Adults with Stuttering
Abstract: Introduction: Stuttering is portrayed by involuntary disruptions in the flow and rhythm of speaking despite the fact that the individual knows precisely what he/she needs to state [1]. Over the past decades, many studies have examined neural mechanisms of stuttering in adults who stutter and have proposed that stuttering may be associated with deficits in the sensorimotor system. Many neuroimaging studies investigating underlying neural deficits of stuttering have reported abnormal …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 6, Issue 2, 2019 · pp. 16–25 Read article
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Speech Intelligibility in Children with Cochlear Implants—A Listener’s Perspective
Abstract: The present study quantifies speech intelligibility of children using cochlear implant (CI) in the listener’s perspectives. The aim of the present study was to compare the speech intelligibility rating (SIR) obtained by CI individuals in three different tasks—words, sentences and conversation—and to compare speech intelligibility of CI users rated by three groups of listeners (speech-language pathologists [SLPs], parents of children with CI and laypersons). Six Tamil speaking children between 5–10 …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 6, Issue 2, 2019 · pp. 26–30 Read article
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Stress Perception among School-age Children
Abstract: Introduction: Prosody is the inflection embedded in speech. The perception of prosody is necessary to understand a spoken utterance, especially to appreciate the intricacies of languages. The influence of prosody is also beyond the boundaries of a sentence and provides speech its emotional tone. Prosody or the supra-segmental is made of stress (accent), intonation (pitch patterns) and the rhythmic (timing) pattern of language. Acoustically, it is described in terms of …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 6, Issue 2, 2019 · pp. 4–9 Read article