Abstract In the past decades, it has been observed a significant increase in the global production of vehicles. This situation is more visible in developing countries, like India, Many of these automobiles are equipped with mobile air-conditioning (MAC) systems in order to improve the comfort and security of the occupants. In contrast to these positive characteristics, the MAC systems are also responsible for greenhouse gas emissions and an increase of on the fuel consumption. Due to environmental regulations, and vehicular efficiency programs, the automotive industry has been researching alternative fluid refrigerants and new technologies to minimize the environmental impact of MAC systems. Considering this situation the aim of this paper is to review the main features of MAC systems currently in use and identify the main Research and Development (R&D) activities related to MAC systems. That can be used on the Indian Market. The literature review indicates that energy efficiency improvements can be obtained by more efficient system components like compressor, high performance heat exchangers, reduction of passenger cabin thermal load, design based on the thermal comfort analysis, improvements based on alternative cycles and reutilization of the waste heat coming out of engine exhaust. Keywords: Mobile air-conditioning, Energy efficiency, Automobile industry Cite this Article Joshi DK. Energy Efficiency in Mobile Air-Conditioning—A Survey. Journal of Refrigeration, Air conditioning, Heating and Ventilation. 2017; 4(2): 1–12p.