Chemical Causes of Leukemia

Nagham Mahmood Aljamali; Ali Jalil Obaid; Maryam Sabah Naser

Abstract

Leukemia was first described by the French physician and surgeon Alfred-Armand-Louis-Marie-Villebeau in 1827. This review talks about Pathologist Rudolf Virchow that gave a more comprehensivedescription in 1845. After Virchow saw a high number of white blood cells in a sample of a patient'sblood The deceased leukemia patient was "dirty green-yellow" rather than the normal red. Neumannconcluded from here that a problem in the bone marrow is responsible for the abnormal blood inleukemia patients. By the 20th century, leukemia was considered a group of diseases rather than asingle disease. By 1947, Boston pathologist Sidney Farber believed from previous experiments thataminopterin, an imitation of folic acid, might cure leukemia in children. Most children with acutelymphoblastic leukemia who are examined show signs of improvement in their bone marrow, but noneof them actually recover. However, this led to more experiments. There are many researchers usedEmile J. Frerich Jr. and Emil Frey III Chemotherapy in an attempt to treat leukemia.

Abstract

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