Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy Review Article
AEGLE MARMELOS: A Review of Its Chemicals Constituents, Biological Activity, and Potential Health Benefits
Abstract
The fruit bael is obtained from the plant name, Aegle marmelos, which is an important medicinal herb found in South Asia. The leaves, stems, bark, and roots are all used in traditional medicine in addition to the fruits. Since ancient times, people have utilized herbs to treat a variety of chronic illnesses. The nutritional and medicinal properties of compounds derived from plants have been confirmed by several scientific investigations. Worldwide concerns over the connection between eating habits and health have led to a surge in interest in plant-derived nutraceuticals. So, to better understand these underutilized fruits and their potential as functional products for the food processing industry, researchers are looking into their functional characteristics. Science-based data on the fruit’s nutritional value is given priority in our analysis.
Keywords
References (33)
- Baral K, Upreti BR. Resource assessment of Bel (Aegle marmelos) and potentiality to establish its processing enterprise in Tanahun district of Nepal. Banko Janakari. 2016;26(1):32-37. doi:10.3126/banko.v26i1.15499
- Saroj PL, More TA, Singh UV. Performance of bael (Aegle marmelos) cultivars under hot arid ecosystem of Rajasthan. Indian J Agric Sci. 2008;78(12):1071–1074.
- Tetali P, Waghchaure C, Daswani PG, Antia NH, Birdi TJ. Ethnobotanical survey of antidiarrhoeal plants of Parinche valley, Pune district, Maharashtra, India. Journal of Ethnopharmacology. 2009;123(2):229-236. doi:10.1016/j.jep.2009.03.013
- Baliga MS, Thilakchand KR, Rai MP, Rao S, Venkatesh P. Aegle marmelos (L.) Correa (Bael) and Its Phytochemicals in the Treatment and Prevention of Cancer. Integrative Cancer Therapies. 2012;12(3):187-196. doi:10.1177/1534735412451320
- Manandhar B, Paudel KR, Sharma B, Karki R. Phytochemical profile and pharmacological activity of Aegle marmelos Linn. Journal of Integrative Medicine. 2018;16(3):153-163. doi:10.1016/j.joim.2018.04.007
- Prabodh CS, Vivek B, Nitin B, Archana S. A review on Bael tree. Nat Prod Radiance. 2007;6(2):171–178.
- Sharma A, Thakur NS. Wild pomegranate (Punica granatum L.): A review on physical and chemical attributes of himalayan wild pomegranate fruit. J Pharmacogn Phytochem. 2018;7(4):1518–1524.
- Dhankhar S, Ruhil S, Balhara M, Dhankhar S, Chhillar AK. Aegle marmelos (Linn.) Correa: A potential source of Phytomedicine. J Med Plant Res. 2011;5(9):1497–1507.
- Sharma IP. Wild Fruits of Uttarakhand (India): Ethnobotanical and Medicinal Uses. International Journal of Complementary & Alternative Medicine. 2017;8(3). doi:10.15406/ijcam.2017.08.00260
- Baliga MS, Bhat HP, Joseph N, Fazal F. Phytochemistry and medicinal uses of the bael fruit (Aegle marmelos Correa): A concise review. Food Research International. 2011;44(7):1768-1775. doi:10.1016/j.foodres.2011.02.008
- Charoensiddhi S, Anprung P. Bioactive compounds and volatile compounds of Thai bael fruit (Aegle marmelos (L.) Correa) as a valuable source for functional food ingredients. Int Food Res J. 2008;15(3):287–295.
- Rastogi RM. Compendium of Indian medicinal plants. Central Drug Research Institute, Lucknow, India. 1990;1:388–389.
- Bajpai VK, Kang SC. Antifungal Activity of Leaf Essential Oil and Extracts of Metasequoia glyptostroboides Miki ex Hu. Journal of the American Oil Chemists' Society. 2009;87(3):327-336. doi:10.1007/s11746-009-1500-6
- Roy SK, Khurdiya DS. Other subtropical fruit. In D. K. Salunkhe, & S. S.Kadam (Eds.), Handbook of fruit science and technology: Production, composition, storage and processing. New York: Marcel Dekker; 1995.
- Rana BK, Singh UP, Taneja V. Antifungal activity and kinetics of inhibition by essential oil isolated from leaves of Aegle marmelos. Journal of Ethnopharmacology. 1997;57(1):29-34. doi:10.1016/s0378-8741(97)00044-5
- Arul V, Miyazaki S, Dhananjayan R. Studies on the anti-inflammatory, antipyretic and analgesic properties of the leaves of Aegle marmelos Corr. Journal of Ethnopharmacology. 2005;96(1-2):159-163. doi:10.1016/j.jep.2004.09.013
- Kar A, Panda S, Bharti S. Relative efficacy of three medicinal plant extracts in the alteration of thyroid hormone concentrations in male mice. Journal of Ethnopharmacology. 2002;81(2):281-285. doi:10.1016/s0378-8741(02)00048-x
- Agrawal SS, Kumar A, Gullaiya S, Dubey V, Nagar A, Tiwari P, et al. Antifertility activity of methanolic bark extract of Aegle marmelos (l.) in male wistar rats. DARU Journal of Pharmaceutical Sciences. 2012;20(1). doi:10.1186/2008-2231-20-94
- Joshi VK, Joshi A, Dhiman KS. The Ayurvedic Pharmacopoeia of India, development and perspectives. Journal of Ethnopharmacology. 2017;197:32-38. doi:10.1016/j.jep.2016.07.030
- Lalita Badam, S.S. Bedekar, Kiran B. Sonawane, Swati P. Joshi, In vitro antiviral activity of bael (Aegle marmelos Corr) upon human coxsackieviruses B1-B6. J Commun Dis. 2002;34:88–99.
- Costa-Lotufo LV, Khan MTH, Ather A, Wilke DV, Jimenez PC, Pessoa C, et al. Studies of the anticancer potential of plants used in Bangladeshi folk medicine. Journal of Ethnopharmacology. 2005;99(1):21-30. doi:10.1016/j.jep.2005.01.041
- Goel RK, Maiti RN, Manickam M, Ray AB. Antiulcer activity of naturally occurring pyrano-coumarin and isocoumarins and their effect on prostanoid synthesis using human colonic mucosa. Indian J Exp Biol. 1997;35(10):1080–1083.
- Bhatti R, Sharma S, Singh J, Singh A, Ishar MPS. Effect of Aegle marmelos (L.) Correa on alloxan induced early stage diabetic nephropathy in rats. Indian J Exp Biol. 2013;51:464–469.
- Sahare KN, Anandhraman V, Meshram VG, Meshram SU, Reddy MVR, Tumane PM, et al. Anti-microfilarial activity of methanolic extract of Vitex negundo and Aegle marmelos and their phytochemical analysis. Indian J Exp Biol. 2008;46:128–131.
- Nugroho AE, Riyanto S, Sukari MA, Maeyama K. Effects of aegeline, a main alkaloid of Aegle Marmelos Correa leaves, on the histamine release from mast cells. Pak J Pharm Sci. 2011;24(3):359–367.
- Laphookhieo S, Phungpanya C, Tantapakul C, Techa S, Tha-in S, Narmdorkmai W. Chemical constituents from Aegle marmelos. Journal of the Brazilian Chemical Society. 2012. doi:10.1590/s0103-50532011000100024
- Ahmad R, Mujeeb M, Ahmad A, Anwar F. Ameliorative effect of Aegle marmelos leaves extract against cisplatin-induced nephrotoxicity and oxidative stress. Bangladesh Journal of Pharmacology. 2015;11(1):101. doi:10.3329/bjp.v11i1.24004
- Waghmare A, Kanyalkar M, Joshi M, Srivastava S. In-vitro metabolic inhibition and antifertility effect facilitated by membrane alteration: Search for novel antifertility agent using nifedipine analogues. European Journal of Medicinal Chemistry. 2011;46(9):3581-3589. doi:10.1016/j.ejmech.2011.05.022
- Kanwar U, Anand RJK, Sanyal SN. The effect of nifedipine, a calcium channel blocker, on human spermatozoal functions. Contraception. 1993;48(5):453-470. doi:10.1016/0010-7824(93)90135-t
- Kar A, Panda S, Bharti S. Relative efficacy of three medicinal plant extracts in the alteration of thyroid hormone concentrations in male mice. Journal of Ethnopharmacology. 2002;81(2):281-285. doi:10.1016/s0378-8741(02)00048-x
- Johnson M. Biochemical variation studies in Aegle marmelos L. Corr: A medicinally important plant. J Chem Pharm Res. 2010;2(6):454–462.
- Panda S, Kar A. Annona squamosa seed extract in the regulation of hyperthyroidism and lipid-peroxidation in mice: Possible involvement of quercetin. Phytomedicine. 2007;14(12):799-805. doi:10.1016/j.phymed.2006.12.001
- Parmar HS, Kar A. Protective role of Mangifera indica, Cucumis melo and Citrullus vulgaris peel extracts in chemically induced hypothyroidism. Chemico-Biological Interactions. 2009;177(3):254-258. doi:10.1016/j.cbi.2008.11.006