3 publications
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Published Subscription
Hepatoprotective Role of Exogenous Melatonin and Insulin Plant (Costus IgneousNak.) Extract against the Streptozotocin Induced Diabetes in RatsBy Adyasha Purohit, Seema Rai, Younis Ahmad Hajam, Hindole Ghosh, Muddasir Basheer
Abstract: The aim of the present study was to compare hepatoprotective efficacy of exogenous melatonin and insulin plant extract against streptozotocin induced hepatic complications. To induce diabetes adult female rat were administrated with STZ (15mg/kg) for consecutive six days. The confirmation of diabetic model was analyzed by blood glucose test. Following confirmation diabetic rat model were treated with exogenous MEL intraperitoneally and plant extract was administered orally. Administration of MEL and …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 1, 2018 · pp. 25–36 Read article →
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Published Subscription
Nephroprotective Effect of Exogenous Melatonin and Plant Extract of Costus Igneous NakBy Sadhana Singroul, Younis Ahmad Hajam, Hindole Ghosh, Seema Rai, Muddasir Basheer
Abstract: Present study was designed to evaluate the nephroprotective effect of exogenous melatonin and insulin plant extract against diabetic induced renal alterations. Diabetic rat model was developed by intraperitoneal treatment of STZ to adult female rat (15 mg/kg) for continuous 6 days. Diabetes was confirmed by checking the blood glucose level. Following confirmation and successful induction, rats were randomly divided into six different groups group viz. group-I (control), group-II (Diabetic control), …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 5, Issue 1, 2018 · pp. 16–24 Read article →
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Published Subscription
Neuroprotective Role of Exogenous Melatonin and Insulin Plant (Costus igneus Nak.) Extract on Brain in Streptozotocin-Induced Diabetes in Female RatBy Divya Gupta, Seema Rai, Younis Ahmad Hajam, Hindole Ghosh, Muddasir Basheer
Abstract: Brain is the one of the most important coordinating and controlling system of the body, which regulates different muscular and neuromuscular activities. The current study was undertaken to explore the neuroprotective role of exogenous melatonin and insulin plant extract in diabetic female rats. Administration of melatonin and plant extract to Streptozotocin (STZ)-induced diabetic rat showed a significant decrease of lipid peroxidation (TBARS) in brain tissue comparable to the control group …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 5, Issue 1, 2018 · pp. 33–41 Read article →